Cross‐site randomized control trial of the Social ABCs caregiver‐mediated intervention for toddlers with autism spectrum disorder

Autism Research - Tập 10 Số 10 - Trang 1700-1711 - 2017
Jessica Brian1, Isabel M. Smith2,3, Lonnie Zwaigenbaum4, Susan E. Bryson2,3
1Autism Research Centre, Bloorview Research Institute/University of Toronto, Toronto, ON
2Autism Research Centre, IWK Health Centre, Halifax, NS
3Departments of Pediatrics and Psychology & Neuroscience Dalhousie University Halifax NS
4Department of Pediatrics, University of Alberta, Edmonton, and Autism Research Centre, Glenrose Rehabilitation Hospital, Edmonton, AB

Tóm tắt

To evaluate the efficacy of the Social ABCs parent‐mediated intervention for toddlers with suspected or confirmed autism spectrum disorder (ASD), through a cross‐site randomized control trial, sixty‐three parent–toddler dyads (toddler age: 16–30 months) were randomized into treatment (Social ABCs) or control (service‐as‐usual) conditions. Video data were obtained at three key time‐points: Baseline; Post‐training (PT; week 12); and Follow‐Up (week 24). Analyses included 62 dyads. Treatment allocation significantly accounted for PT gains, all favouring the Treatment group, in (1) child functional vocal responsiveness to parent prompts (R2 = 0.43, P < .001), (2) child vocal initiations (R2 = 0.28, P < .001), (3) parent smiling (R2 = 0.09, P = .017), and (4) fidelity of implementation (R2 = 0.71, P < .001). A trend was observed for increased social orienting (R2 = 0.06, P = 0.054); gains in parent smiling significantly predicted increases in child smiling and social orienting. Parents in the treatment condition reported significant gains in self‐efficacy following the intervention (P = 0.009). No differential effects emerged for performance on standardized measures. The Social ABCs is a relatively low‐resource, efficacious intervention, with potential to be a cost‐effective means of intervening at the first signs of possible ASD. Autism Res 2017, 10: 1700–1711. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

Clinical Trial Title: Social ABCs for Toddlers with Signs of Autism Spectrum Disorder: RCT of a Parent‐Mediated Intervention http//ClinicalTrials.gov identifier: NCT02428452.

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Autism Research

Tập 10 Số 10

1700-1711

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