Correlation between Fitness and Genetic Diversity

Conservation Biology - Tập 17 Số 1 - Trang 230-237 - 2003
David Reed1, Richard Frankham1
1Key Centre for Biodiversity and Bioresources, Department of Biological Sciences, Macquarie University,
New South Wales, 2109, Australia

Tóm tắt

Abstract: Genetic diversity is one of the three forms of biodiversity recognized by the World Conservation Union ( IUCN ) as deserving conservation. The need to conserve genetic diversity within populations is based on two arguments: the necessity of genetic diversity for evolution to occur, and the expected relationship between heterozygosity and population fitness. Because loss of genetic diversity is related to inbreeding, and inbreeding reduces reproductive fitness, a correlation is expected between heterozygosity and population fitness. Long‐term effective population size, which determines rates of inbreeding, should also be correlated with fitness. However, other theoretical considerations and empirical observations suggest that the correlation between fitness and heterozygosity may be weak or nonexistent. We used all the data sets we could locate (34 ) to perform a meta‐analysis and resolve the issue. Data sets were included in the study, provided that fitness, or a component of fitness, was measured for three or more populations along with heterozygosity, heritability, and/or population size. The mean weighted correlation between measures of genetic diversity, at the population level, and population fitness was 0.4323. The correlation was highly significant and explained 19% of the variation in fitness. Our study strengthens concerns that the loss of heterozygosity has a deleterious effect on population fitness and supports the IUCN designation of genetic diversity as worthy of conservation.

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Tài liệu tham khảo

Allendorf F. W., 1986, Conservation Biology: the science of scarcity and diversity, 57

10.1111/j.1558-5646.1998.tb02249.x

Ballou J. D., 1997, Effects of ancestral inbreeding on genetic load in mammalian populations., Journal of Heredity, 88, 169, 10.1093/oxfordjournals.jhered.a023085

Beardmore J., 1983, Genetics and conservation: a reference for managing wild animal and plant populations, 125

10.1038/hdy.1993.20

10.1093/genetics/114.4.1191

10.1016/S0006-3207(99)00150-0

10.1146/annurev.ecolsys.30.1.479

10.1146/annurev.es.18.110187.001321

10.1017/S0016672399004152

Charlesworth B., 2000, Evolutionary genetics, 369

10.1111/j.1558-5646.1999.tb04516.x

Crnokrak P., 1999, Inbreeding depression in the wild., Heredity, 83, 260, 10.1038/sj.hdy.6885530

10.1111/j.1558-5646.1999.tb04541.x

10.1046/j.1523-1739.1992.06040549.x

Falconer D. S., 1996, Introduction to quantitative genetics

10.2307/2446416

10.1046/j.1365-2745.1998.00246.x

10.1146/annurev.ge.29.120195.001513

10.1046/j.1523-1739.1996.10061500.x

Franklin I., 1980, Conservation biology: an evolutionary‐ecological perspective, 135

10.1139/x91-097

Garten C., 1976, Relationships between aggressive behavior and genetic heterozygosity in the oldfield mouse, Peromyscus polionotus., Evolution, 41, 80

Gilligan D., 2001, Conservation genetics and long‐term survival: testing models using Drosophila

10.1007/978-1-4757-2504-9_6

10.1146/annurev.ecolsys.31.1.139

10.2307/1941887

10.1046/j.1523-1739.1995.09010126.x

10.1038/hdy.1997.134

Houle D., 1989, Allozyme associated heterosis in Drosophila melanogaster., Genetics, 123, 789, 10.1093/genetics/123.4.789

Hunter J. E., 1990, Methods of meta‐analysis: correcting errors and bias in research findings.

10.1017/CBO9780511623486

10.1046/j.1523-1739.1998.97123.x

10.1111/j.1558-5646.1998.tb03715.x

10.1046/j.1523-1739.1999.98278.x

Lande R., 1995, Population management for survival & recovery, 318

10.1111/j.1558-5646.1985.tb04077.x

10.1098/rspb.1998.0285

10.4159/9780674040243

Lipsey M. W., 2000, Practical meta‐analysis

10.1111/j.1558-5646.1989.tb02628.x

10.1111/j.1523-1739.2000.99345.x

Lynch M., 1998, Genetics and analysis of quantitative traits

10.1038/46941

Mather K., 1973, Genetical structure of populations

10.1111/j.1558-5646.1994.tb01364.x

McNeely J. A., 1990, Conserving the world's biological diversity

10.1111/j.1558-5646.1999.tb04547.x

10.1111/j.1523-1739.1991.tb00120.x

Oosterhout C. V., 2000, Captive metapopulations of the butterfly Bicyclus anynana

10.1046/j.1420-9101.1995.8060739.x

10.2307/2261591

10.1146/annurev.ecolsys.31.1.441

10.1002/zoo.1430050202

Reed D. H., 1998, Population size, selection, and mutation accumulation

10.1111/j.1469-1795.2000.tb00082.x

Reed D. H., 2001, Fitness, genetic load, and purging in experimental populations of the housefly., Conservation Genetics, 2, 57, 10.1023/A:1011567018530

10.1111/j.0014-3820.2001.tb00629.x

10.1111/j.1469-1795.1999.tb00053.x

Saccheri I. J., 1996, Severe inbreeding depression and rapid fitness rebound in the butterfly Bicyclus anynana (  Satyridae  )., Evolution, 50, 2000, 10.2307/2410758

Saccheri I. J., 1999, Inbreeding of bottlenecked butterfly populations: estimation using the likelihood of changes in marker allele frequencies., Genetics, 151, 1053, 10.1093/genetics/151.3.1053

Soulé M. E., 1986, Conservation biology: the science of scarcity and diversity

Soulé M. E., 1980, Conservation biology: an evolutionary‐ecological perspective

10.1007/978-3-0348-8510-2_5

10.1111/j.1558-5646.1996.tb03882.x

10.1126/science.282.5394.1695

10.1038/hdy.1993.84

10.1111/j.1095-8312.1993.tb00925.x

Wright S., 1977, Evolution and the genetics of populations. 3

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Conservation Biology

Tập 17 Số 1

230-237

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