Continuous human uterine NK cell differentiation in response to endometrial regeneration and pregnancy

Science immunology - Tập 6 Số 56 - 2021
Benedikt Strunz1, Jonna Bister1, Hanna Jönsson1, Iva Filipovic1, Ylva Crona Guterstam1,2,3, Egle Kvedaraite1,4, Natalie Sleiers1, Bogdan Dumitrescu5, Mats Brännström6, Antonio Lentini7, Björn Reinius7, Martin Cornillet1, Tim Willinger1, Sebastian Gidlöf2,3,8, Russell S. Hamilton9,10, Martin A. Ivarsson1, Niklas K. Björkström1
1Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
2Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
3Department of Gynecology and Reproductive Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.
4Childhood Cancer Research Unit, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden
5Department of Obstetrics and Gynecology, Mälarsjukhuset, Eskilstuna, Sweden.
6Department of Obstetrics and Gynecology, University of Gothenburg, Gothenburg, Sweden
7Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
8Department of Obstetrics and Gynecology, Stockholm South General Hospital, Stockholm, Sweden
9Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
10Department of Genetics, University of Cambridge, Cambridge, UK

Tóm tắt

Human uterine NK cells continuously differentiate in response to the monthly regeneration of the endometrium and during pregnancy.

Từ khóa


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