Congenital gemistocytic astrocytoma in a fetus

Springer Science and Business Media LLC - Tập 22 - Trang 168-171 - 2005
Michimasa Nozaki1, Akiko Ohnishi2, Takamitsu Fujimaki3, Kazuo Nagashima2, Kazutoshi Cho4, Yutaka Sawamura5
1Department of Neurosurgery, Kin-ikyo Chuo Hospital, Sapporo, Japan
2Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine, Sapporo, Japan
3Department of Neurosurgery, Teikyo University School of Medicine, Tokyo, Japan
4Maternity and Perinatal Care Center, Hokkaido University School of Medicine, Sapporo, Japan
5Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo, Japan

Tóm tắt

Congenital brain tumors, especially tumors diagnosed before birth, are very rare. This report presents a case of a congenital gemistocytic astrocytoma diagnosed by antenatal intrauterine ultrasound. An intrauterine MRI revealed hydrocephalus and a mass lesion including massive hemorrhage in the right occipital lobe of a fetus. The patient was delivered by cesarean section and a total excision of the hemorrhagic tumor was carried out on the third day of his life. The histological study revealed gemistocytic astrocytoma (WHO grade II). Neither adjuvant chemotherapy nor radiation was given after the first surgery. Ten months after his birth, a recurrent tumor was depicted on follow-up MRI. The second total excision of the recurrent tumor and chemotherapy using cisplatin and vincristine were performed. The patient is free of disease at the age of 2 years and 6 months.

Tài liệu tham khảo

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