Congenital Poisoning by Polychlorinated Biphenyls and Their Contaminants in Taiwan

American Association for the Advancement of Science (AAAS) - Tập 241 Số 4863 - Trang 334-336 - 1988
Walter J. Rogan1, Beth C. Gladen, Kun‐Long Hung, Sung-Soo Koong, L Y Shih, James S. Taylor, Yu‐Chin Wu, Deyi Yang, N. Beth Ragan, Chao‐Chin Hsu
1National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.

Tóm tắt

In 1979, a mass poisoning occurred in Taiwan from cooking oil contaminated by thermally degraded polychlorinated biphenyls. Because these chemicals persist in human tissue, children born to female patients after the outbreak were exposed in utero. In 1985, 117 children born to affected women and 108 unexposed controls were examined and evaluated. The exposed children were shorter and lighter than controls; they had abnormalities of gingiva, skin, nails, teeth, and lungs more frequently than did controls. The exposed children showed delay of developmental milestones, deficits on formal developmental testing, and abnormalities on behavioral assessment. These findings are most consistent with a generalized disorder of ectodermal tissue. This syndrome is one of very few documented to result from transplacental exposure to pollutant chemicals.

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American Association for the Advancement of Science (AAAS)

Tập 241 Số 4863

334-336

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