Conductive Polymeric Ionic Liquid/Fe3O4 Nanocomposite as an Efficient Catalyst for the Voltammetric Determination of Amlodipine Besylate

Journal of AOAC International - Tập 100 Số 2 - Trang 406-413 - 2017
Fariba Fathirad1,2, Ali Mostafavi3, Daryoush Afzali4
1Shahid Bahonar University of Kerman, Faculty of Sciences, Department of Chemistry, Kerman, Iran; and Shahid Bahonar University of Kerman, Young Research Society, Kerman, Iran
2Shahid Bahonar University of Kerman, Young Research Society, Kerman, Iran
3Shahid Bahonar University of Kerman, Faculty of Sciences, Department of Chemistry, Kerman, Iran
4Graduate University of Advanced Technology, Institute of Science and High Technology and Environmental Sciences, Department of Environment, Kerman, Iran

Tóm tắt

Abstract A novel conductive polymeric ionic liquid (IL)-Fe3O4 nanocomposite (represented as PIL-Fe3O4) based on inorganic-organic hybrid material was synthesized using two different methods. Nuclear magnetic resonance, Fourier transform infrared, X-ray diffraction, and field emission scanning electron microscopy characterized the structures of IL, Fe3O4 nanoparticles, and PIL-Fe3O4. The electrochemical sensors based on PIL-Fe3O4-modified glassy carbon electrode were fabricated, and each of these nanocomposites was examined for the ability to determine amlodipine besylate (AMD). The electrochemical study of the modified electrodes, as well as its efficiency for the electro-oxidation of AMD, was described in 0.1 M phosphate-buffered solution (pH 7.0) using voltammetric methods. The results exhibit a linear dynamic range from 1 to 500 nM and a detection limit of 0.36 nM. Finally, the modified electrode was used for the determination of AMD in pharmaceutical and biological samples.

Từ khóa


Tài liệu tham khảo

Thông tin
Thông tin xuất bản

Journal of AOAC International

Tập 100 Số 2

406-413

Thông tin tác giả