Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

Brain - Tập 141 Số 2 - Trang 422-458 - 2018
Chad A. Tagge1,2, Andrew M. Fisher1,2, Olga Minaeva1,3,2, Amanda Gaudreau-Balderrama1,2, Juliet A. Moncaster3,4,2, Xiaolei Zhang5, Mark Wojnarowicz4,2, Noel Casey2,6, Haiyan Lu7, Olga N. Kokiko‐Cochran7, Sudad Saman8, Maria Ericsson9, Kristen D. Onos10, Ronel Veksler11, Vladimir V. Senatorov12, Asami Kondo13, Xiao Zhen Zhou13, Omid Miry5, Linnea R. Vose5, Katisha R. Gopaul5, Chirag Upreti5, Christopher J. Nowinski14,14, Robert C. Cantu14,14,15, Victor E. Alvarez14,16, Audrey M. Hildebrandt16, Erich S. Franz1,2, Janusz Konrad1, James A. Hamilton4, Ning Hua4, Yorghos Tripodis14,17, Andrew T. Anderson18, Gareth R. Howell10, Daniela Kaufer19,12, Garth F. Hall8, Kun Ping Lu13, Richard M. Ransohoff7, Robin O. Cleveland20, Neil W. Kowall14,14,16, Thor D. Stein14,14,16, Bruce T. Lamb7, Bertrand R. Huber14,14,21, William C. Moss18, Alon Friedman22,11, Patric K. Stanton5, Ann C. McKee14,14,16, Lee E. Goldstein1,3,4,2,6
1Boston University, College of Engineering, Boston, MA 02215, USA
2Molecular Aging and Development Laboratory, Boston University School of Medicine, Boston, MA 02118, USA.
3Boston University Photonics Center, Boston University, Boston, MA 02215, USA.
4Boston University School of Medicine, Boston, MA 02118, USA
5Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY 10595, USA
6The Center for Biometals and Metallomics, Boston University School of Medicine, Boston, MA 02118, USA
7Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
8Department of Biological Sciences, University of Massachusetts–Lowell, Lowell, MA 01854, USA
9Electron Microscope Facility, Harvard Medical School, Boston, MA 02115, USA.
10The Jackson Laboratory, Bar Harbor, ME 04609, USA
11Departments of Brain and Cognitive Sciences, Physiology and Cell Biology, Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
12Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA
13Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
14Alzheimer's Disease Center, CTE Program, Boston University School of Medicine, Boston, MA 02118, USA
15Department of Neurosurgery, Emerson Hospital, Concord, MA 01742, USA.
16VA Boston Healthcare System, Boston, MA 02130, USA
17Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
18Lawrence Livermore National Laboratory, Livermore, CA 94551 USA
19Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA
20Institute of Biomedical Engineering, University of Oxford, Oxford OX3 7DQ, UK
21National Center for PTSD, VA Boston Healthcare System, Boston, MA, 02130, USA
22Department of Medical Neuroscience, Brain Repair Center, Dalhousie University, Halifax, B3H 4R2, Canada

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