Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma

PLoS Genetics - Tập 8 Số 4 - Trang e1002654
Janey L. Wiggs1, Brian L. Yaspan2, Michael A. Hauser3, Jae H. Kang4, R. Rand Allingham3, Lana M. Olson2, Wael Abdrabou1, Bao Jian Fan1, Dan Y. Wang1, Wendy Brodeur5, Donald L. Budenz6, Joseph Caprioli7, Andrew Crenshaw5, Kristy Crooks3, E. DelBono1, Kimberly F. Doheny8, David S. Friedman9, Douglas Gaasterland10, Terry Gaasterland11, Cathy C. Laurie12, Richard K. Lee13, Paul R. Lichter14, Stephanie Loomis4,1, Yutao Liu3, Felipe A. Medeiros15, Cathy McCarty16, Daniel B. Mirel5, Sayoko E. Moroi14, David C. Musch17,14, Anthony Realini18, Frank W. Rozsa14, Joel S. Schuman19, Kathleen M. Scott14, Kuldev Singh20, Joshua D. Stein14, Edward H. Trager14, Paul VanVeldhuisen21, Douglas Vollrath22, Gadi Wollstein19, Sachiko Yoneyama17,14, Kang Zhang15, Robert N. Weinreb15, Jason Ernst5,23, Manolis Kellis5,23, Tomohiro Masuda9, Donald J. Zack9, Julia E. Richards17,14, Margaret A. Pericak‐Vance24, Louis R. Pasquale4,1, Jonathan L. Haines2
1Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States of America.
2Vanderbilt University School of Medicine, Center for Human Genetics Research, Nashville, Tennessee, United States of America
3Duke University School of Medicine, Durham, North Carolina, United States of America
4Department of Medicine and Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
5Broad Institute of Harvard and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America
6Department of Ophthalmology, University of North Carolina School of Medicine, Durham, North Carolina, United States of America
7Department of Ophthalmology, University of California Los Angeles, Los Angeles, California, United States of America
8Center for Inherited Disease Research, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
9Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
10Eye Doctors of Washington D.C., Washington D.C., United States of America
11Institute for Genomic Medicine and Marine Biology Research Division, University of California San Diego, San Diego, California, United States of America
12Department of Biostatistics, University of Washington, Seattle, Washington, United States of America
13Department of Ophthalmology, University of Miami, Miami, Florida, United States of America
14Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, United States of America
15Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America
16Essentia Institute of Rural Health, Duluth, Minnesota, United States of America
17Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America
18Department of Ophthalmology, West Virginia University School of Medicine, Morgantown, West Virginia, United States of America
19Department of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
20Department of Ophthalmology, Stanford University, Palo Alto, California, United States of America
21The EMMES Corporation, Rockville, Maryland, United States of America.
22Department of Genetics, Stanford University, Palo Alto, California, United States of America
23Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
24Department of Human Genetics, University of Miami School of Medicine, Miami, Florida, United States of America

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PLoS Genetics

Tập 8 Số 4

e1002654

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