Comment on epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study

Springer Science and Business Media LLC - 2019
Makoto Aoki1, Toshikazu Abe2
1Department of Emergency Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan
2Department of General Medicine, Juntendo University, Tokyo, Japan

Tóm tắt

AbstractThe aim of this Letter to the Editor was to report some important biases in a recently published Article. We agreed with the notion by Yamamoto et al. that the effects of epinephrine regarding was limited without hemostasis, however, this study had major limitations such as no information on etiology of traumatic cardiac arrest (hemorrhagic or on non-hemorrhagic) and on hemostatic treatment. The results of this study should be interpreted with caution and further analysis is necessary. Finally, we commented on the necessity of future study regarding another vasopressor (ie; vasopressin) on traumatic cardiac arrest based on current evidence.

Từ khóa


Tài liệu tham khảo

Yamamoto R, Suzuki M, Hayashida K, Yoshizawa J, Sakurai A, Kitamura N, et al. Epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study. Scand J Trauma Resusc Emerg Med. 2019;27(1):74.

Aoki M, Abe T, Oshima K. Association of prehospital epinephrine administration with survival among patients with traumatic cardiac arrest caused by traffic collisions. Sci Rep. 2019;9(1):9922.

Lin YR, Wu MH, Chen TY, Syue YJ, Yang MC, Lee TH, et al. Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest. Crit Care. 2019;23(1):101.

Sims CA, Holena D, Kim P, Pascual J, Smith B, Martin N, et al. Effect of low-dose supplementation of arginine vasopressin on need for blood product transfusions in patients with trauma and hemorrhagic shock: a randomized clinical trial. JAMA Surg. 2019. https://doi.org/10.1001/jamasurg.2019.2884.

Thông tin
Thông tin xuất bản

Springer Science and Business Media LLC

Thông tin tác giả