Cocktail of REGN Antibodies Binds More Strongly to SARS-CoV-2 Than Its Components, but the Omicron Variant Reduces Its Neutralizing Ability

Journal of Physical Chemistry B - Tập 126 Số 15 - Trang 2812-2823 - 2022
Hung Van Nguyen1, Pham Dang Lan2,3, Daniel A. Nissley4, Edward P. O’Brien5,6,7, Mai Suan Li1
1Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw, Poland
2Faculty of Physics and Engineering Physics, VNUHCM-University of Science, 227, Nguyen Van Cu Street, District 5, 749000 Ho Chi Minh City, Vietnam
3Life Science Lab, Institute for Computational Science and Technology, Quang Trung Software City, Tan Chanh Hiep Ward, District 12, 729110 Ho Chi Minh City, Vietnam
4Department of Statistics, University of Oxford, Oxford Protein Bioinformatics Group, OX1 2JD Oxford, United Kingdom
5Bioinformatics and Genomics Graduate Program, The Huck Institutes of the Life Sciences, Penn State University, University Park, Pennsylvania 16802, United States
6Department of Chemistry, Penn State University, University Park, Pennsylvania 16802, United States
7Institute for Computational and Data Sciences, Penn State University, University Park, Pennsylvania 16802, United States

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