Clinical features and outcomes of Legionnaires' disease in solid organ transplant recipients

Transplant Infectious Disease - Tập 11 Số 1 - Trang 78-82 - 2009
Carlota Gudiol1, Carolina García‐Vidal1, Núria Sabé1, R. Verdaguer2, Laura Lladó3, Josep Roca4, S Gil-Vernet5, Jordi Carratalà1
1Infectious Disease Department (Program of Infections in Cancer and Transplant Patients), Hospital Universitari de Bellvitge, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, University of Barcelona, Barcelona, Spain,
2Microbiology Department, Hospital Universitari de Bellvitge, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, University of Barcelona, Barcelona, Spain,
3Liver Transplant Unit, Hospital Universitari de Bellvitge, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, University of Barcelona, Barcelona, Spain,
4Heart Transplant Unit, Hospital Universitari de Bellvitge, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, University of Barcelona, Barcelona, Spain
5Nephrology Department, Hospital Universitari de Bellvitge, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, University of Barcelona, Barcelona, Spain

Tóm tắt

Abstract: We identified 14 cases of Legionnaires' disease occurring in 2946 solid organ transplant recipients from 1985 to 2007. Most cases were sporadic and community acquired. The recent introduction of the urinary antigen test has accelerated diagnosis and allows prompt institution of adequate therapy. The overall mortality rate in our series was 14.3%.

Từ khóa


Tài liệu tham khảo

10.1586/14787210.4.6.995

Chow JW, 1998, Legionella, a major opportunistic pathogen in transplant recipients, 13, 132

10.1097/00007890-199602150-00013

10.1164/ajrccm.149.3.8118629

Singh N, 2004, Prevention of Legionnaires' disease in transplant recipients, recommendations for a standardized approach, 6, 58

Singh N, 1993, Legionella infection in liver transplant recipients, implications for management, 56, 1549

Bangsborg JM, 1995, Nosocomial legionellosis in three heart–lung transplant patients, case reports and environmental observations, 14, 99

Sax H, 2002, Legionnaires' disease in a renal transplant recipient, nosocomial or home-grown?, 74, 890

10.1111/j.1399-3062.2004.00053.x

10.1378/chest.125.6.2135

Mykietiuk A, 2005, Clinical outcomes for hospitalized patients with Legionella pneumonia in the antigenuria era, the influence of levofloxacin therapy, 40, 794

Blázquez Garrido MR, 2005, Antimicrobial chemotherapy for Legionnaires disease, levofloxacin versus macrolides, 40, 800

10.1378/chest.128.3.1401

10.1086/515040

Ampel NM, 1990, Legionella infection in transplant patients, Semin Respir Infect, 5, 30

Prodinger WM, 1994, Legionella pneumonia in transplant recipients, a cluster of cases of eight years' duration, 26, 191

10.1007/BF01695659

10.1093/jac/40.5.673

Edelstein PH., 1998, Antimicrobial chemotherapy for legionnaires' disease, time for a change, 129, 328

Roig J, 2003, Legionnaires' disease, a rational approach to therapy, 5, 1119

10.1007/BF01646407