Clinical biology of nitric oxide

Moncada, 1991, Nitric oxide: physiology, pathophysiology and pharmacology, Pharmacol Rev, 43, 109

Moncada, 1993, The L-arginine-nitric oxide pathway, N Engl J Med, 329, 2002, 10.1056/NEJM199312303292706

Mitchell, 1916, The origin of the nitrates in the urine, J Biol Chem, 24, 461, 10.1016/S0021-9258(18)87531-7

Tannenbaum, 1928, Nitrite and nitrate are formed by endogenous synthesis in the human intestine, Science, 200, 1487, 10.1126/science.663630

Iyengar, 1967, Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst, Proc Natl Acad Sci U S A, 84, 6369, 10.1073/pnas.84.18.6369

Marletta, 1988, Macrophage oxidation of L-arginine to nitrite and nitrate: nitric acid is an intermediate, Biochemistry, 27, 8706, 10.1021/bi00424a003

Furchgott, 1980, The obligatory role of the endothelial cells in the relaxation of arterial smooth muscle by acetylcholine, Nature, 288, 373, 10.1038/288373a0

Palmer, 1987, Nitric oxide release accounts for the biological activity of endothelium-derived relaxation factor, Nature, 327, 524, 10.1038/327524a0

Palmer, 1988, Vascular endothelial cells synthesize nitric oxide from L-arginine, Nature, 333, 664, 10.1038/333664a0

Ignarro, 1987, Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide, Proc Natl Acad Sci U S A, 84, 9265, 10.1073/pnas.84.24.9265

Garthwaite, 1989, NMDA receptor activation incudes nitric oxide synthesis from arginine in rat brain slices, Eur J Pharmacol, 172, 413, 10.1016/0922-4106(89)90023-0

Garthwaite, 1991, Glutamate, nitric oxide and cell-cell signalling in the nervous system, Trends Neurosci, 14, 60, 10.1016/0166-2236(91)90022-M

Koshland, 1992, Nitric oxide: the molecule of the year, Science, 258, 1861, 10.1126/science.1470903

Ignarro, 1989, Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein, Circ Res, 65, 1, 10.1161/01.RES.65.1.1

Forstermann, 1994, Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions, Hypertension, 23, 1121, 10.1161/01.HYP.23.6.1121

Ignarro, 1990, Biosynthesis and metabolism of endothelium-derived nitric oxide, Annu Rev Pharmacol Toxicol, 30, 535, 10.1146/annurev.pa.30.040190.002535

Henry, 1993, EPR characterization of molecular targets for NO in mammalian cells and organelles, FASEB J, 7, 1124, 10.1096/fasebj.7.12.8397130

Murad, 1994, Regulation of cytosolic guanylyl cyclase by nitric oxide: the NO-cyclic GMP signal transduction system, Adv Pharmacol, 26, 19, 10.1016/S1054-3589(08)60049-6

Feigl, 1988, EDRF — a protective factor?, Nature, 331, 490, 10.1038/331490a0

Cooke, 1993, Cytoprotective effects of nitric oxide, Circulation, 88, 2451, 10.1161/01.CIR.88.5.2451

Beckman, 1990, Apparent hydroxyl radical production of peroxynitrite: implications for endothelial injury from nitric oxide and superoxide, Proc Natl Acad Sci U S A, 87, 1620, 10.1073/pnas.87.4.1620

Beckman, 1993, Pathological implications of nitric oxide, superoxide and peroxynitrite formation, Biochem Soc Trans, 21, 330, 10.1042/bst0210330

Zhu, 1992, Bactericidal activity of peroxynitrite, Arch Biochem Biophys, 298, 452, 10.1016/0003-9861(92)90434-X

Radi, 1991, Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide, Arch Biochem Biophys, 288, 481, 10.1016/0003-9861(91)90224-7

Bauer, 1992, Peroxynitrite inhibits sodium uptake in rat colonic membrane vesicles, Biochem Biophys Acta, 1104, 87, 10.1016/0005-2736(92)90135-9

Ischiropoulos, 1992, Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase, Arch Biochem Biophys, 298, 431, 10.1016/0003-9861(92)90431-U

Rubanyi, 1989, Evidence that EDRF may be identical with an S-nitrothiol and not with free nitric oxide (NO), Circulation, 80, II-281

Stamler, 1992, Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin, Proc Natl Acad Sci U S A, 89, 7674, 10.1073/pnas.89.16.7674

Clancy, 1994, Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary, Proc Natl Acad Sci U S A, 91, 3680, 10.1073/pnas.91.9.3680

Keaney, 1993, NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties, J Clin Invest, 91, 1582, 10.1172/JCI116364

Mülsch, 1993, Release of EDRF decreases endothelial iron content (abstract), FASEB J, 7, A129

Mülsch, 1993, Formation and release of dinitrosyl iron complexes by endothelial cells, Biochem Biophys Res Commun, 196, 1303, 10.1006/bbrc.1993.2394

Vanin, 1991, Endothelium-derived relaxing factor is a nitrosyl iron complex with thiol ligands, FEBS Lett, 289, 1, 10.1016/0014-5793(91)80894-9

Vedernikov, 1992, Similarity between the vasorelaxing activity of dinitrosyl cysteine complexes and endothelium-derived relaxing factor, Eur J Pharmacol, 211, 313, 10.1016/0014-2999(92)90386-I

Vallance, 1992, Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure, Lancet, 339, 572, 10.1016/0140-6736(92)90865-Z

Nathan, 1992, Nitric oxide as a secretory product of mammalian cells, FASEB J, 6, 3051, 10.1096/fasebj.6.12.1381691

Sessa, 1994, The nitric oxide synthase family of proteins, J Vasc Res, 31, 131, 10.1159/000159039

Dinerman, 1993, Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease, Circ Res, 73, 217, 10.1161/01.RES.73.2.217

Bredt, 1991, Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase, Nature, 351, 714, 10.1038/351714a0

Pou, 1992, Generation of superoxide by purified brain nitric oxide synthase, J Biol Chem, 267, 24 173, 10.1016/S0021-9258(18)35745-4

Heinzel, 1992, Ca2+/ calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase, Biochem J, 281, 627, 10.1042/bj2810627

Michel, 1993, Phosphorylation and subcellular translocation of endothelial nitric oxide synthase, Proc Natl Acad Sci U S A, 90, 6252, 10.1073/pnas.90.13.6252

Brune, 1991, Phosphorylation of nitric oxide synthase by protein kinase A, Biochem Biophys Res Commun, 181, 921, 10.1016/0006-291X(91)91279-L

Nakane, 1991, Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase, Biochem Biophys Res Commun, 180, 1396, 10.1016/S0006-291X(05)81351-8

Buga, 1993, Negative feedback regulation of endothelial cell function by nitric oxide, Circ Res, 73, 808, 10.1161/01.RES.73.5.808

Marsden, 1993, Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene, J Biol Chem, 268, 17 478, 10.1016/S0021-9258(19)85359-0

Marczin, 1993, Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents, Br J Pharmacol, 109, 603, 10.1111/j.1476-5381.1993.tb13613.x

Chartrain, 1994, Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene, J Biol Chem, 269, 6765, 10.1016/S0021-9258(17)37441-0

Morris, 1994, New insights into the regulation of inducible nitric oxide synthesis, Am J Physiol, 266, E829-39

Davies, 1993, Mechanical stress mechanisms and the cell. An endothelial paradigm, Circ Res, 72, 239, 10.1161/01.RES.72.2.239

Radomski, 1987, Endogenous NO inhibits human platelet adhesion to vascular endothelium, Lancet, ii, 1057, 10.1016/S0140-6736(87)91481-4

Radomski, 1990, Characterization of the L-arginine: nitric oxide pathway in human platelets, Br J Pharmacol, 101, 325, 10.1111/j.1476-5381.1990.tb12709.x

Kubes, 1991, Nitric oxide: an endogenous modulator of leukocyte adhesion, Proc Natl Acad Sci U S A, 88, 4651, 10.1073/pnas.88.11.4651

Kubes, 1993, Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells, FASEB J, 7, 1293, 10.1096/fasebj.7.13.8405815

Clancy, 1992, Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase, J Clin Invest, 90, 1116, 10.1172/JCI115929

McCall, 1989, Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion, Biochem J, 261, 293, 10.1042/bj2610293

Vidal, 1992, Involvement of nitric oxide in tumor cell adhesion to cytokine-activated endothelial cells, J Cardiovasc Pharmacol, 20, S155-9, 10.1097/00005344-199204002-00044

Bachmann, 1994, Nitric oxide in the kidney: synthesis localization and function, Am J Kidney Dis, 24, 112, 10.1016/S0272-6386(12)80170-3

Alberola, 1992, Role of nitric oxide in mediating renal response to volume expansion, Hypertension, 19, 780, 10.1161/01.HYP.19.6.780

Mattson, 1992, Role of nitric oxide in renal papillary blood flow and sodium excretion, Hypertension, 19, 766, 10.1161/01.HYP.19.6.766

Zatz, 1991, Effects of acute nitric oxide inhibition on rat glomerular microcirculation, Am J Physiol, 261, F360-3

Brezis, 1991, Role of nitric oxide in renal medullary oxygenation. Studies in isolated and intact rat kidneys, J Clin Invest, 88, 390, 10.1172/JCI115316

Radermacher, 1992, Importance of NO/EDRF for glomerular and tubular function: studies in the isolated perfused rat kidney, Kidney Int, 41, 1549, 10.1038/ki.1992.225

Beierwaltes, 1992, Endothelium modulates renal blood flow but not autoregulation, Am J Physiol, 262, F943-9

Mundel, 1992, Expression of nitric oxide synthase in kidney macula densa cells, Kidney Int, 42, 1017, 10.1038/ki.1992.382

Wilcox, 1992, Nitric oxide synthase in macula densa regulates glomerular capillary pressure, Proc Natl Acad Sci U S A, 89, 11 993, 10.1073/pnas.89.24.11993

Ito, 1993, Evidence for the role of nitric oxide in macular densa control of glomerular hemodynamics, J Clin Invest, 92, 1093, 10.1172/JCI116615

Deng, 1993, Locally produced EDRF controls preglomerular resistance and ultrafiltration coefficient, Am J Physiol, 264, F212-15

Sigmon, 1993, Renal nitric oxide and angiotensin II. Interactions in renovascular hypertension, Hypertension, 22, 237, 10.1161/01.HYP.22.2.237

Scholz, 1993, Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney, J Clin Invest, 91, 1088, 10.1172/JCI116266

Vidal, 1988, Endothelium-derived relaxing factor inhibits renin release, Eur J Pharmacol, 149, 401, 10.1016/0014-2999(88)90679-6

Beierwaltes, 1991, Nonprostanoid endothelium-derived factors inhibit renin release, Hypertension, 19, 68

Schricker, 1993, Liberators of NO exert a dual effect on renin secretion from isolated mouse renal juxtaglomerular cells, Am J Physiol, 265, F180-6

Li, 1991, Evidence that part of the NANC relaxant response of the guinea-pig trachea to electrical field stimulation is mediated by nitric oxide, Br J Pharmacol, 102, 91, 10.1111/j.1476-5381.1991.tb12137.x

Belvisi, 1992, Nitric oxide is the endogenous neurotransmittor of bronchodilator nerves in humans, Eur J Pharmacol, 210, 221, 10.1016/0014-2999(92)90676-U

Barnes, 1993, Nitric oxide and airways, Eur Resp J, 6, 163, 10.1183/09031936.93.06020163

Dinh-Xuan, 1992, Endothelial modulation of pulmonary vascular tone, Eur Respir J, 5, 757, 10.1183/09031936.93.05060757

Pearl, 1993, Inhaled nitric oxide: the past, the present and the future, Anesthesiology, 78, 413, 10.1097/00000542-199303000-00002

Pepke-Zaba, 1991, Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension, Lancet, 338, 1173, 10.1016/0140-6736(91)92033-X

Kinsella, 1992, Low-dose inhalation nitric oxide in persistent pulmonary hypertension of the newborn, Lancet, 340, 819, 10.1016/0140-6736(92)92687-B

Frostell, 1993, Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation, Anesthesiology, 78, 427, 10.1097/00000542-199303000-00005

Snyder, 1991, Nitric oxide as a neuronal messenger, Trends Pharmacol Sci, 12, 125, 10.1016/0165-6147(91)90526-X

Schuman, 1994, Nitric oxide and synaptic function, Annu Rev Neurosci, 17, 153, 10.1146/annurev.ne.17.030194.001101

Bohme, 1991, Possible involvement of nitric oxide in long-term potentation, Eur J Pharmacol, 199, 379, 10.1016/0014-2999(91)90505-K

O'Dell, 1991, Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger, Proc Natl Acad Sci U S A, 88, 11 285, 10.1073/pnas.88.24.11285

Schuman, 1991, A requirement for the intercellular messenger nitric oxide in long-term potentiation, Science, 254, 1503, 10.1126/science.1720572

Costa, 1976, The peristaltic reflex: an analysis of the nerve pathways and their pharmacology, Naunyn Schmeidebergs Arch Pharmacol, 294, 47, 10.1007/BF00692784

Stark, 1991, Effect of nitric oxide on circular muscle of the canine small intestine, J Physiol, 444, 743, 10.1113/jphysiol.1991.sp018904

Stark, 1992, Role of nitric oxide in gastrointestinal and hepatic function and disease, Gastroenterology, 103, 1928, 10.1016/0016-5085(92)91454-C

Yuan, 1995, Pharmacological evidence that nitric oxide may be a retrograde messenger in the enteric nervous system, Br J Pharmacol, 114, 428, 10.1111/j.1476-5381.1995.tb13244.x

Stark, 1993, Nitric oxide mediates inhibitory nerve input in human and canine jejunum, Gastroenterology, 104, 398, 10.1016/0016-5085(93)90407-4

Bredt, 1990, Localization of nitric oxide synthase indicating a neural role for nitric oxide, Nature, 347, 768, 10.1038/347768a0

MacNaughton, 1989, Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach, Life Sci, 45, 1869, 10.1016/0024-3205(89)90540-7

Whittle, 1990, Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat, Br J Pharmacol, 99, 607, 10.1111/j.1476-5381.1990.tb12977.x

Kaufman, 1993, Nitric oxide inhibits resting sphincter of Oddi activity, Am J Surg, 165, 74, 10.1016/S0002-9610(05)80407-6

Schmidt, 1992, Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides, Science, 255, 721, 10.1126/science.1371193

Anderson, 1993, Pharmacology of lower urinary tract smooth muscles and penile erectile tissues, Pharmacol Rev, 45, 253

Ignarro, 1990, Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle, Biochem Biophys Res Commun, 170, 843, 10.1016/0006-291X(90)92168-Y

Kim, 1991, A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle, J Clin Invest, 88, 112, 10.1172/JCI115266

Holmquist, 1991, L-NG-nitro arginine inhibits nonadrenergic noncholinergic relaxation of human isolated corpus cavernosum, Acta Physiol Scand, 141, 441, 10.1111/j.1748-1716.1991.tb09103.x

Burnett, 1993, Immunohistochemical localization of nitric oxide synthase in the autocrine innervation of the human penis, J Urol, 150, 73, 10.1016/S0022-5347(17)35401-0

Ross, 1986, The pathogenesis of atherosclerosis — an update, N Engl J Med, 314, 488, 10.1056/NEJM198602203140806

Flavahan, 1992, Atherosclerosis or lipoprotein-induced endothelial dysfunction. Potential mechanisms underlying reduction in EDRF/nitric oxide activity, Circulation, 85, 1927, 10.1161/01.CIR.85.5.1927

Harrison, 1987, Alterations of vascular reactivity in atherosclerosis, Circ Res, 61, 74, 10.1161/res.61.5_supplement.ii-74

Fuster, 1992, Progression-regression of atherosclerosis: molecular, cellular and clinical bases, Circulation, 82, 1

Powell, 1994, Smoking, nitric oxide and the endothelium, Br J Surg, 81, 785, 10.1002/bjs.1800810602

Harrison, 1993, Endothelial dysfunction in the coronary microcirculation: a new clinical entity or an experimental finding?, J Clin Invest, 91, 1, 10.1172/JCI116156

Rubanyi, 1991, Cardiovascular Significance of Endothelium Derived Vasoactive Factors

Hayashi, 1992, Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implication for atherosclerosis, Proc Natl Acad Sci U S A, 89, 11 259, 10.1073/pnas.89.23.11259

Cooke, 1992, Antiatherogenic affects of L-arginine in the hypercholesterolemic rabbit, J Clin Invest, 90, 1168, 10.1172/JCI115937

Cooke, 1991, Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta, Circulation, 83, 1057, 10.1161/01.CIR.83.3.1057

Cooke, 1994, Is NO an endogenous antiatherogenic molecule?, Arterioscler Thromb, 14, 653, 10.1161/01.ATV.14.5.653

Creager, 1992, L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans, J Clin Invest, 90, 1248, 10.1172/JCI115987

Harrison, 1987, Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis, J Clin Invest, 80, 1808, 10.1172/JCI113276

Linz, 1992, Role of bradykinin in the cardiac effects of angiotensin-converting enzyme inhibitors, J Cardiovasc Pharmacol, 20, S83-90

Fuster, 1992, The pathogenesis of coronary artery disease and the acute coronary syndromes (I) and (II), N Engl J Med, 326, 242, 10.1056/NEJM199201233260406

Luscher, 1990, Imbalance of endothelium-derived relaxing factors and contracting factors. A new concept in hypertension?, Am J Hypertens, 3, 317, 10.1093/ajh/3.4.317

Panza, 1990, Abnormal endothelium-dependent relaxation in patients with essential hypertension, N Engl J Med, 323, 22, 10.1056/NEJM199007053230105

Dzau, 1988, Evolving concepts of the renin-angiotensin system. Focus on renal and vascular mechanisms, Am J Hypertens, 1, 334S, 10.1093/ajh/1.4.334S

Nakazono, 1991, Does superoxide underlie the pathogenesis of hypertension?, Proc Natl Acad Sci U S A, 88, 10045, 10.1073/pnas.88.22.10045

Luscher, 1988, Relaxing and Contracting Factors: Biological and Clinical Research, 459

Chen, 1991, L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats, J Clin Invest, 88, 1559, 10.1172/JCI115467

Nakaki, 1990, L-arginine-induced hypotension, Lancet, 336, 696, 10.1016/0140-6736(90)92196-O

Luscher, 1987, Antihypertensive treatment normalizes decreased endothelium-dependent relaxation in rats with salt-induced hypertension, Hypertension, 9, 193, 10.1161/01.HYP.9.6_Pt_2.III193

Ruderman, 1984, Diabetes as an atherogenic factor, Progress in Cardiovascular Research, 26, 373, 10.1016/0033-0620(84)90011-2

Schmidt, 1994, Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions, Arterioscler Thromb, 14, 1521, 10.1161/01.ATV.14.10.1521

Bucala, 1991, Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes, J Clin Invest, 87, 432, 10.1172/JCI115014

Wilkins, 1988, Cerebral Vasospasm

Faraci, 1994, Nitric oxide and the cerebral circulation, Stroke, 25, 692, 10.1161/01.STR.25.3.692

Iadecola, 1993, Does nitric oxide mediate the increases in cerebral blood flow elicited by hypercapnia?, Proc Natl Acad Sci U S A, 89, 3913, 10.1073/pnas.89.9.3913

Wang, 1992, Effect of nitric oxide blockade by N-nitro-L-arginine on cerebral blood flow response to changes in carbon dioxide tension, J Cereb Blood Flow Metab, 12, 947, 10.1038/jcbfm.1992.131

Iadecola, 1994, Nitric oxide synthase inhibition and cerebrovascular regulation, J Cereb Blood Flow Metab, 14, 175, 10.1038/jcbfm.1994.25

Dalkara, 1994, The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia, Brain Pathol, 4, 49, 10.1111/j.1750-3639.1994.tb00810.x

Malinski, 1993, Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion, J Cereb Blood Flow Metab, 13, 355, 10.1038/jcbfm.1993.48

Zhang, 1993, Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats, Stroke, 24, 2016, 10.1161/01.STR.24.12.2016

Trifiletti, 1992, Neuroprotective effects of NG-nitro-L-arginine in focal stroke in the 7-day old rat, Eur J Pharmacol, 218, 197, 10.1016/0014-2999(92)90168-4

Iadecola, 1995, Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage, Am J Physiol, 268, R286-92

Reif, 1993, Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage, Neuroreport, 4, 566, 10.1097/00001756-199305000-00026

Dawson, 1993, Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures, J Neurosci, 13, 2651, 10.1523/JNEUROSCI.13-06-02651.1993

Lefer, 1991, Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia, FASEB J, 5, 2029, 10.1096/fasebj.5.7.2010056

Quillen, 1990, Ischemia-reperfusion impairs endothelium-dependent relaxation of coronary microvessels but does not affect large arteries, Circulation, 82, 586, 10.1161/01.CIR.82.2.586

Pearson, 1990, Long-term impairment of endothelium-dependent relaxation to aggregating platelets after reperfusion injury in canine coronary arteries, Circulation, 81, 1921, 10.1161/01.CIR.81.6.1921

Weselcouch, 1995, Inhibition of nitric oxide synthesis does not affect ischemic preconditioning in isolated perfused rat hearts, Am J Physiol, 268, H242-9

Sheridan, 1991, Role of leukocytes in coronary vascular endothelial injury due to ischemia and reperfusion, Circ Res, 69, 1566, 10.1161/01.RES.69.6.1566

Nakanishi, 1993, Intracoronary L-arginine infusion during reperfusion reduces infarct size and neutrophil accumulation, Scientific Conference on Functional and Structural Mechanisms of Vascular Control, 86

Davies, 1994, Pathobiology of intimal hyperplasia, Br J Surg, 81, 1254, 10.1002/bjs.1800810904

Shimokawa, 1987, Porcine coronary arteries with regenerated endothelium have a reduced endothelium-dependent responsiveness to aggregating platelets and serotonin, Circ Res, 61, 256, 10.1161/01.RES.61.2.256

Shimokawa, 1989, Natural course of the impairment of endothelium-dependent relaxations after balloon endothelium removal in porcine coronary artery. Possible dysfunction of a pertussis toxin sensitive G protein, Circ Res, 65, 740, 10.1161/01.RES.65.3.740

Joly, 1992, Balloon injury and interleukin-1β induce nitric oxide synthase activity in rat carotid arteries, Circ Res, 71, 331, 10.1161/01.RES.71.2.331

McNamara, 1993, L-arginine inhibits catheter-induced intimal hyperplasia, Biochem Biophys Res Commun, 193, 291, 10.1006/bbrc.1993.1622

Tarry, 1993, Nitric oxide precursor speeds recovery of endothelial-dependent vasorelaxation and reduces intimal hyperplasia after endothelial injury, Surgical Forum, XLIV, 384

Davies, 1993, The integrity of experimental vein graft endothelium: implications on the etiology of early graft failure, Eur J Vasc Surg, 7, 156, 10.1016/S0950-821X(05)80756-X

Davies, 1995, Pathophysiology of vein graft failure, Eur J Vasc Endovasc Surg, 9, 7, 10.1016/S1078-5884(05)80218-7

Davies, 1995, A comparative study of EDRF-mediated relaxation and smooth muscle cell function in arterial and venous vein bypass grafts, Cardiovascular Surgery

Davies, 1994, Reduction of experimental vein graft intimal hyperplasia and preservation of nitric oxide-mediated relaxation by the nitric oxide precursor L-arginine, Surgery, 116, 557

Davies, 1995, Control of the accelerated vein graft atheroma with the nitric oxide precursor: L-arginine, J Surg Res, 59, 35, 10.1006/jsre.1995.1129

Cross, 1994, Long-term human vein graft contractility and morphology: a functional and histopathological study of retrieved coronary vein grafts, Br J Surg, 81, 699, 10.1002/bjs.1800810524

Davies, 1995, Constitutive nitric oxide synthase is expressed and nitric oxide-mediated relaxation is preserved in retrieved human aorto-coronary vein grafts, J Surg Res, 58, 732, 10.1006/jsre.1995.1116

Luscher, 1988, Difference between endothelium-dependent relaxation in arterial and in venous coronary bypass grafts, N Engl J Med, 319, 462, 10.1056/NEJM198808253190802

Luscher, 1992, Vascular biology of coronary bypass grafts, Coron Artery Dis, 3, 225, 10.1097/00019501-199202000-00011

Nussler, 1993, Inflammation, immunoregulation, and inducible nitric oxide synthase, J Leukoc Biol, 54, 171, 10.1002/jlb.54.2.171

Wolfe, 1995, Use of nitric oxide synthase inhibitors as a novel treatment for septic shock, Ann Pharmacother, 29, 36, 10.1177/106002809502900108

Thiemermann, 1994, The role of the L-arginine-nitric oxide pathway in circulatory shock, Adv Pharmacol, 28, 45, 10.1016/S1054-3589(08)60493-7

Brady, 1993, Circulatory failure in septic shock. Nitric oxide: too much of a good thing?, Br Heart J, 70, 103, 10.1136/hrt.70.2.103

Finkel, 1992, Negative inotropic effects of cytokines on the heart mediated by nitric oxide, Science, 257, 387, 10.1126/science.1631560

Nava, 1991, Inhibition of nitric oxide synthesis in septic shock; how much is beneficial?, Lancet, 338, 1555, 10.1016/0140-6736(91)92375-C

Kilbourn, 1990, NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide, Proc Natl Acad Sci U S A, 87, 3629, 10.1073/pnas.87.9.3629

Pastor, 1994, Effects of L-arginine and L-nitro-arginine treatment on blood pressure and cardiac output in a rabbit endotoxin shock model, Crit Care Med, 22, 465, 10.1097/00003246-199403000-00017

Petros, 1991, Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock, Lancet, 338, 1557, 10.1016/0140-6736(91)92376-D

Geroulanos, 1992, Inhibition of NO synthesis in septic shock, Lancet, 339, 435

Hibbs, 1988, Nitric oxide: a cytotoxic activated macrophage effector molecule, Biochem Biophys Res Commun, 157, 87, 10.1016/S0006-291X(88)80015-9

Nathan, 1991, Role of nitric oxide synthesis in macrophage antimicrobial activity, Curr Opin Immunol, 3, 65, 10.1016/0952-7915(91)90079-G

Kolb, 1992, Nitric oxide a pathogenic factor in autoimmunity, Immunol Today, 13, 157, 10.1016/0167-5699(92)90118-Q

Hoffman, 1990, Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine, J Immunol, 145, 2220, 10.4049/jimmunol.145.7.2220

Albina, 1991, Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway, J Surg Res, 50, 403, 10.1016/0022-4804(91)90210-D

Langrehr, 1992, Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat, J Clin Invest, 90, 679, 10.1172/JCI115911

Lancaster, 1992, EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft, J Biol Chem, 267, 10994, 10.1016/S0021-9258(19)49865-7

Vanderwinden, 1992, Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis, N Engl J Med, 327, 511, 10.1056/NEJM199208203270802

Boughton-Smith, 1990, Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat, Eur J Pharmacol, 191, 485, 10.1016/0014-2999(90)94185-Z

Hutcheson, 1990, Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat, Br J Pharmacol, 101, 815, 10.1111/j.1476-5381.1990.tb14163.x

Schirgi-Degen, 1995, Significance of nitric oxide in the stimulation of intestinal fluid absorption in the rat jejunum. in vivo, Br J Pharmacol, 114, 13, 10.1111/j.1476-5381.1995.tb14899.x

Middleton, 1993, Increased nitric oxide synthesis in ulcerative colitis, Lancet, 341, 465, 10.1016/0140-6736(93)90211-X

Harbrecht, 1992, Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury, J Surg Leukoc Biol, 52, 390, 10.1002/jlb.52.4.390

Kuo, 1994, Nitric oxide decreases oxidant-mediated hepatocyte injury, J Surg Res, 56, 594, 10.1006/jsre.1994.1094

Guarner, 1993, Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia, Hepatology, 18, 1139, 10.1002/hep.1840180520

Midgley, 1991, Nitric oxide in liver failure, Lancet, 338, 1590, 10.1016/0140-6736(91)92407-S

Bomzon, 1994, The nitric oxide hypothesis and the hyperdynamic circulation in cirrhosis, Hepatology, 20, 1343, 10.1002/hep.1840200535