Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

Aging Cell - Tập 15 Số 5 - Trang 973-977 - 2016
Carolyn M Roos1, Bin Zhang1, Allyson K. Palmer2, Mikołaj Ogrodnik2,3, Tamar Pirtskhalava2, Nassir M Thalji1, Michael A Hagler1, Diana Jurk3, Leslie Smith1, Grace Casaclang‐Verzosa1, Yi Zhun Zhu2, Marissa J. Schafer2, Tamar Tchkonia2, James L. Kirkland4,2, Jordan D. Miller4,1,2
1Department of Surgery, Mayo Clinic, Rochester, MN, USA
2Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA
3Newcastle University Institute for Aging, Newcastle University, Newcastle Upon Tyne, UK
4Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA

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10.1038/ng1382

10.1038/nature10600

10.1161/01.ATV.19.8.1960

10.1161/01.cir.0000437740.48606.d1

10.1152/ajpheart.00292.2006

10.1161/01.ATV.17.11.2744

10.1038/ncomms1708

10.1161/01.CIR.0000129501.88485.1f

10.1093/gerona/52A.6.B331

10.1161/01.STR.0000257967.86132.01

10.1152/ajpheart.01108.2009

10.1165/rcmb.2006-0169OC

10.1152/ajpheart.00735.2012

10.1016/j.freeradbiomed.2013.08.185

10.1152/ajpheart.01405.2006

10.1016/S0169-328X(99)00067-4

10.1016/j.atherosclerosis.2012.05.003

10.1038/nature04019

10.1152/ajprenal.90302.2008

10.1161/CIRCRESAHA.111.261388

10.1111/acel.12344

10.1111/acel.12445