Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes
Tóm tắt
Từ khóa
Tài liệu tham khảo
Ly KN, Xing J, Klevens RM, Jiles RB, Ward JW, Holmberg SD (2012) The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007. Ann Intern Med 156(4):271–278
Cai Z, Yi M, Zhang C, Luo G (2005) Mutagenesis analysis of the rGTP-specific binding site of hepatitis C virus RNA-dependent RNA polymerase. J Virol 79(18):11607–11617
Polis CB, Shah SN, Johnson KE, Gupta A (2007) Impact of maternal HIV coinfection on the vertical transmission of hepatitis C virus: a meta-analysis. Clin Infect Dis 44(8):1123–1131
Wantuck JM, Ahmed A, Nguyen MH (2013) The epidemiology and therapy of chronic hepatitis C genotypes 4, 5 and 6. Aliment Pharmacol Ther 39(2):137–147
Kanda T, Imazeki F, Yokosuka O (2010) New antiviral therapies for chronic hepatitis C. Hepatol Int 4(3):548–561
Sansonno D (2012) Immune-related disorders and extrahepatic diseases in chronic HCV infection. Clin Dev Immunol 2012:509309
Neumann AU, Lam NP, Dahari H, Davidian M, Wiley TE, Mika BP et al (2000) Differences in viral dynamics between genotypes 1 and 2 of hepatitis C virus. J Infect Dis 182(1):28–35
Xing Y, Hogquist KA (2012) T-cell tolerance: central and peripheral. Cold Spring Harb Perspect Biol 4(6):1–15
Di Somma MM, Somma F, Gilardini Montani MS, Mangiacasale R, Cundari E, Piccolella E (1999) TCR engagement regulates differential responsiveness of human memory T cells to Fas (CD95)-mediated apoptosis. J Immunol 162(7):3851–3858
Cavani A, Nasorri F, Ottaviani C, Sebastiani S, De Pità O, Girolomoni G (2003) Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals. J Immunol 171(11):5760–5768
Calabrese F, Pontisso P, Pettenazzo E, Benvegnù L, Vario A, Chemello L et al (2000) Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levels. Hepatology 31(5):1153–1159
Núñez M, Soriano V, López M, Ballesteros C, Cascajero A, González-Lahoz J et al (2006) Coinfection with hepatitis C virus increases lymphocyte apoptosis in HIV-infected patients. Clin Infect Dis 43(9):1209–1212
Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L et al (2009) Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458(7235):206–210
Feuth T, Arends JE, Fransen JH, Nanlohy NM, van Erpecum KJ, Siersema PD et al (2013) Complementary role of HCV and HIV in T-cell activation and exhaustion in HIV/HCV coinfection. PLoS One 8(3):e59302
Nielsen SD, Afzelius P, Ersbøll AK, Nielsen JO, Hansen JE (1998) Expression of the activation antigen CD69 predicts functionality of in vitro expanded peripheral blood mononuclear cells (PBMC) from healthy donors and HIV-infected patients. Clin Exp Immunol 114(1):66–72
Hoffmann TK, Dworacki G, Tsukihiro T, Meidenbauer N, Gooding W, Johnson JT et al (2002) Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance. Clin Cancer Res 8(8):2553–2562
Vig M, Srivastava S, Kandpal U, Sade H, Lewis V, Sarin A et al (2004) Inducible nitric oxide synthase in T cells regulates T cell death and immune memory. J Clin Invest 113(12):1734–1742
McCloskey TW, Oyaizu N, Kaplan M, Pahwa S (1995) Expression of the Fas antigen in patients infected with human immunodeficiency virus. Cytometry 22(2):111–114
Hashimoto F, Oyaizu N, Kalyanaraman VS, Pahwa S (1997) Modulation of Bcl-2 protein by CD4 cross-linking: a possible mechanism for lymphocyte apoptosis in human immunodeficiency virus infection and for rescue of apoptosis by interleukin-2. Blood 90(2):745–753
Cuconati A, White E (2002) Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection. Genes Dev 16(19):2465–2478
Elbim C, Monceaux V, Mueller YM, Lewis MG, François S, Diop O et al (2008) Early divergence in neutrophil apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates. J Immunol 181(12):8613–8623
Zheng L, Fisher G, Miller RE, Peschon J, Lynch DH, Lenardo MJ (1995) Induction of apoptosis in mature T cells by tumor necrosis factor. Nature 377(6547):348–351
Ding F, Shao ZW, Yang SH, Wu Q, Gao F, Xiong LM (2012) Role of mitochondrial pathway in compression-induced apoptosis of nucleus pulposus cells. Apoptosis 17(6):579–590
Rukoyatkina N, Mindukshev I, Walter U, Gambaryan S (2013) Dual role of the p38 MAPK/cPLA2 pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists. Cell Death Dis 4:e931
Brault C, Levy PL, Bartosch B (2013) Hepatitis C virus-induced mitochondrial dysfunctions. Viruses 5(3):954–980
Shankar EM, Che KF, Messmer D, Lifson JD, Larsson M (2011) Expression of a broad array of negative costimulatory molecules and Blimp-1 in T cells following priming by HIV-1 pulsed dendritic cells. Mol Med 17(3–4):229–240
Barathan M, Mariappan V, Shankar EM, Abdullah BJ, Goh KL, Vadivelu J (2013) Hypericin-photodynamic therapy leads to interleukin-6 secretion by HepG2 cells and their apoptosis via recruitment of BH3 interacting-domain death agonist and caspases. Cell Death Dis 4:e697
Obojes K, Andres O, Kim KS, Däubener W, Schneider-Schaulies J (2005) Indoleamine 2, 3-dioxygenase mediates cell type-specific anti-measles virus activity of gamma interferon. J Virol 79(12):7768–7776
Higashitani K, Kanto T, Kuroda S, Yoshio S, Matsubara T, Kakita N et al (2013) Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection. J Gastroenterol 48(5):660–670
Larsson M, Shankar EM, Che KF, Saeidi A, Ellegård R, Barathan M et al (2013) Molecular signatures of T-cell inhibition in HIV-1 infection. Retrovirology 10:31
Rue CA, Jarvis MA, Knoche AJ, Meyers HL, DeFilippis VR, Hansen SG et al (2004) A cyclooxygenase -2 homologue encoded by rhesus cytomegalovirus is a determinant for endothelial cell tropism. J Virol 78(22):12529–12536
Abdalla SI, Sanderson IR, Fitzgerald RC (2005) Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells. Carcinogenesis 26(9):1627–1633
Wang W, Bergh A, Damber J (2005) Cyclooxygenase-2 expression correlates with local chronic inflammation and tumor neovascularization in human prostate cancer tumor neovascularization in human prostate cancer. Clin Cancer Res 11(9):3250–3256
Garden GA, Budd SL, Tsai E, Hanson L, Kaul M, D’Emilia DM et al (2002) Caspase cascades in human immunodeficiency virus-associated neurodegeneration. J Neurosci 22(10):4015–4024
Lin TK, Cheng CH, Chen SD, Liou CW, Huang CR, Chuang YC (2012) Mitochondrial dysfunction and oxidative stress promote apoptotic cell death in the striatum via cytochrome c/caspase-3 signaling cascade following chronic rotenone intoxication in rats. Int J Mol Sci 13(7):8722–8839
Núñez O, Fernández-Martínez A, Majano PL, Apolinario A, Gómez-Gonzalo M, Benedicto I et al (2004) Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins. Gut 53(11):1665–1672
Khaitan A, Unutmaz D (2011) Revisiting immune exhaustion during HIV infection. Curr HIV/AIDS Rep 8(1):4–11
Ou R, Zhang M, Huang L, Moskophidis D (2008) Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection. J Virol 82(7):3353–3368
Wang S, El-Deiry WS (2003) TRAIL and apoptosis induction by TNF-family death receptors. Oncogene 22(53):8628–8633
Gasper-Smith N, Crossman DM, Whitesides JF, Mensali N, Ottinger JS, Plonk SG et al (2008) Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design. J Virol 82(15):7700–7710
Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM et al (2002) Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 122(2):366–375
Fink SL, Cookson BT (2005) Eukaryotic cells apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect Immun 73(4):1907–1916
Kaminskyy V, Zhivotovsky B (2010) To kill or be killed: how viruses interact with the cell death machinery. J Intern Med 267(5):473–482
Vanlandschoot P, Leroux-Roels G (2003) Viral apoptotic mimicry: an immune evasion strategy developed by the hepatitis B virus? Trends Immunol 24(3):144–147
Hou W, Liu KZ, Li MW, Wo JE (2005) Effect of IFNalpha-2a on Fas expression and apoptosis rate of peripheral blood cytotoxic T cells in patients with hepatitis B. Hepatobiliary Pancreat Dis Int 4(3):403–405
Gupta A, Nagilla P, Le HS, Bunney C, Zych C, Thalamuthu A et al (2011) Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1). PLoS One 6(7):e22730
Yahya RS, Ghanem OH, Foyouh AA, Atwa M, Enany SA (2013) Role of interleukin-8 and oxidative stress in patients with hepatocellular carcinoma. Clin Lab 59(9–10):969–976
Tardif KD, Waris G, Siddiqui A (2005) Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol 13(4):159–163
Arciello M, Gori M, Balsano C (2013) Mitochondrial dysfunctions and altered metals momeostasis: new weapons to counteract HCV-related oxidative stress. Oxid Med Cell Longev 2013:971024
Li S, Zhao Y, He X, Kim TH, Kuharsky DK, Rabinowich H et al (2002) Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis. J Biol Chem 277(30):26912–26920
Zhang Z, Xu X, Lu J, Zhang S, Gu L, Fu J et al (2011) B and T lymphocyte attenuator down-regulation by HIV-1 depends on type I interferon and contributes to T-cell hyperactivation. J Infect Dis 203(11):1668–1678
Xu XS, Zhang Z, Gu LL, Wang FS (2009) BTLA characterization and its association with disease progression in patients with chronic HIV-1 infection. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25(12):1158–1160
Le Bouteiller P, Barakonyi A, Giustiniani J, Lenfant F, Marie-Cardine A, Aguerre-Girr M et al (2002) Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity. Proc Natl Acad Sci USA 99(26):16963–16968
del Rio ML, Lucas CL, Buhler L, Rayat G, Rodriguez-Barbosa JI (2010) HVEM/LIGHT/BTLA/CD160 cosignaling pathways as targets for immune regulation. J Leukoc Biol 87(2):223–235
Volkmann X, Fischer U, Bahr MJ, Ott M, Lehner F, Macfarlane M et al (2007) Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver. Hepatology 46(5):1498–1508
Speletas M, Argentou N, Germanidis G, Vasiliadis T, Mantzoukis K, Patsiaoura K et al (2011) Foxp3 expression in liver correlates with the degree but not the cause of inflammation. Mediators Inflamm 2011:827565
Vali B, Jones RB, Sakhdari A, Sheth PM, Clayton K, Yue FY et al (2010) HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression. Eur J Immunol 40(9):2493–2505
Kroy DC, Ciuffreda D, Cooperrider JH, Tomlinson M, Hauck GD, Aneja J et al (2014) Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors. Gastroenterology 146(2):550–561
Aref S, Abdullah D, Fouda M, El Menshawy N, Azmy E, Bassam A et al (2011) Neutrophil apoptosis in neutropenic patients with hepatitis C infection: role of caspases 3, 10, and GM-CSF. Indian J Hematol Blood Transfus 27(2):81–87
Simonin Y, Disson O, Lerat H, Antoine E, Binamé F, Rosenberg AR et al (2009) Calpain activation by hepatitis C virus proteins inhibits the extrinsic apoptotic signaling pathway. Hepatology 50(5):1370–1379
Schleich K, Lavrik IN (2013) Systems biology of death receptor-induced apoptosis. In: Lavrik IN (ed) Systems biology of apoptosis. Springer, Science + Business Media, New York, pp 33–57
Wang W, Sun Q, Wu Z, Zhou D, Wei J, Xie H et al (2013) Mitochodrial dysfuntion-related genes in hepatocellular carcinoma. Front Biosci (Landmark Ed) 18:1141–1149
Tischner D, Woess C, Ottina E, Villunger A (2010) Bcl-2-regulated cell death signalling in the prevention of autoimmunity. Cell Death Dis 21:e48
Feuth T, Van Baarle D, Hoepelman AI, Van Erpecum KJ, Siersema PD, Arends JE (2014) Activation of extrinsic apoptosis pathway in HCV monoinfected and HIV-HCV coinfected patients, irrespective of liver disease severity. Apoptosis 19(7):1128–1135