Chromium released from leather – I: exposure conditions that govern the release of chromium(III) and chromium(VI)

Contact Dermatitis - Tập 72 Số 4 - Trang 206-215 - 2015
Yolanda Hedberg1,2, Carola Lidén2, Inger Odnevall Wallinder1
1Division of Surface and Corrosion Science, Department of Chemistry School of Chemical Science and Engineering, KTH Royal Institute of Technology Drottning Kristinas väg 51 SE‐10044 Stockholm Sweden
2Unit of Occupational and Environmental Dermatology Institute of Environmental Medicine, Karolinska Institutet Nobels väg 13 Box 210, SE‐17177 Stockholm Sweden

Tóm tắt

SummaryBackgroundApproximately 1–3% of the adult population in Europe is allergic to chromium (Cr). A new restriction in REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) based on the ISO 17075 standard has recently been adopted in the EU to limit Cr(VI) in consumer and occupational leather products.ObjectivesThe aim of this study was to critically assess key experimental parameters in this standard on the release of Cr(III) and Cr(VI) and their relevance for skin exposure.Material and methodsFour differently tanned, unfinished, leather samples were systematically investigated for their release of Cr(III) and Cr(VI) in relation to surface area, key exposure parameters, temperature, ultraviolet irradiation, and time.ResultsAlthough the total release of Cr was largely unaffected by all investigated parameters, except exposure duration and temperature, the Cr oxidation state was highly dynamic, with reduced amounts of released Cr(VI) with time, owing to the simultaneous release of reducing agents from the leather. Significantly more Cr(III) than Cr(VI) was released from the Cr‐tanned leather for all conditions tested, and it continued to be released in artificial sweat up to at least 1 week of exposure.ConclusionsSeveral parameters were identified that influenced the outcome of the ISO 17075 test.

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Tài liệu tham khảo

10.1016/j.ecoenv.2010.01.011

10.1007/s00216-009-3417-1

10.1016/j.jhazmat.2013.01.048

Samitz M, 1966, Patch test reactions to hexavalent and trivalent chromium compounds, Arch Dermatol, 94, 304, 10.1001/archderm.1966.01600270054010

10.1111/1523-1747.ep12531034

10.1021/tx9002726

10.1111/j.1600-0536.2009.01577.x

10.1111/cod.12291

10.1007/s00420-010-0581-8

10.1136/oemed-2011-100220

EC.2009. Available at:http://eur‐lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:342:0059:0209:en:PDF(last accessed 14 November 2014).

10.1111/j.1600-0536.1993.tb03318.x

10.1111/j.0105-1873.2003.00149.x

10.1111/j.1365-2133.2009.09405.x

10.1111/j.1600-0536.2010.01798.x

10.1080/10643380590521436

Beghetto V, 2013, The leather industry: a chemistry insight part I: an overview of the industrial process, Sci Ca'Foscari, 1, 13

10.1039/cs9972600111

German Federal Institute for Risk Assessment.Chromium (VI) in leather clothing and shoes problematic for allergy sufferers! 2007. Available at:http://www.bfr.bund.de/en/press_information/2007/10/chromium__vi__in_leather_clothing_and_shoes_problematic_for_allergy_sufferers_‐9575.html(last accessed 14 November 2014).

10.1111/j.1600-0536.2011.02053.x

10.1034/j.1600-0536.2002.470301.x

10.1111/j.0105-1873.2006.00824.x

Ollenhauer‐Ries C, 2007, Beseitigung von Chrom VI aus Lederartikeln, Leder & Häute Markt, 4, 8

Johansen J D, 2011, Survey and Health Assessment (Sensitisation Only) of Chromium in Leather Shoes

European Chemicals Agency (Echa).2013. Available at:http://echa.europa.eu/en/view‐article/‐/journal_content/title/seac‐concludes‐on‐scientific‐opinions‐for‐two‐restriction‐proposa‐1(last accessed 14 November 2014).

ISO. Leather – Chemical Tests – Determination of Chromium(VI) Content. ISO 17075 2007. International Organization for Standardization Geneva.

10.1001/archderm.1958.01560110058008

Long A, 2000, Potential chemical mechanisms causing false positive results in hexavalent chromium determination, J Soc Leath Technol Chem, 84, 74

10.1111/j.0105-1873.2003.0230.x

10.1001/archderm.1965.01600090041007

10.1111/1523-1747.ep12724462

10.1001/archderm.1966.01600190040006

Fregert S, 1966, Allergic reactions to trivalent chromium compounds, Arch Dermatol, 93, 711, 10.1001/archderm.1966.01600240077013

10.1038/jid.1967.83

10.1111/j.1600-0536.1992.tb03284.x

CEN. Reference test Method for Release of Nickel from all Post Assemblies which are Inserted into Pierced Parts of the Human Body and Articles Intended to Come into Direct and Prolonged Contact with the Skin. EN-1811:2011 2011. European Committee for Standardization Brussels.

10.1016/j.envpol.2011.02.014

UN.The Globally Harmonized System of Classification and Labelling of Chemicals Annex 10 Guidance on transformation/dissolution of metals and metal compounds in aqueous media 2009.

10.1021/ja01600a014

Rydin S, 2002, Investigation of the Content of Cr (VI) and Cr (III) in Leather Products on the Danish Market

Graf D, 2001, Formation of Cr (VI) traces in chrome tanned leathers: causes, prevention, and latest findings, J Am Leather Chem Assoc, 96, 169

10.1016/j.talanta.2004.01.010

10.1016/j.jhazmat.2014.08.061

Hauber C, 1999, Untersuchungen zur Entstehung und Vermeidung von Chromat in Leder, Leder & Häute Markt, 9, 25

Meyndt R, 2011, Relationships in the formation of hexavalent chrome [Cr(VI)], World Leather, 14

Cory N J, 1997, A practical discussion session to deal with opportunities for improvement of customer/end user satisfaction, J Am Leather Chem Assoc, 92, 119

Font J, 1999, Influence of various factors on chromium (6) formation by photo‐ageing, J Soc Leath Technol Chem, 83, 300

10.1590/S0104-66322011000200006

10.1016/j.jclepro.2004.07.003

Palop R, 2008, Leather ageing and hexavalent chromium formation as a function of the fatliquoring agent. Part II: chrome retanned leathers, J Soc Leath Technol Chem, 92, 233

Palop R, 2008, Leather ageing and hexavalent chromium formation as a function of the fatliquoring agent. Part I. Chrome tanned leathers, J Soc Leath Technol Chem, 92, 200

Jambunathan S, 2000, Determination of hexavalent chromium in leather extracts by the diphenylcarbazide (IUC‐18) procedure: pitfalls and refinements, J Soc Leath Technol Chem, 84, 63

HauberC.Formation prevention & determination of Cr(VI) in leather – a short overview of recent publications UNIDO report.2000.

Sammarco U, 1998, Formazione di Cr (VI) nelle pelli e possibilità di eliminazione, Cuoio, Pelli, Materie Concianti, 74, 83

C. Hauber

Saddington M, 1999, Trivalent chromium to hexavalent chromium, Leather, 201, 33

NickolausG.Untersuchungen zur Entstehung und Vermeidung von Chrom VI‐Verbindungen im Verlauf der Lederverarbeitung. In:52 VGCT Meeting Aachen 2000.

10.1016/j.jhazmat.2010.03.037

Font J, 1999, Presence of chromium (VI) in sheepskins: influence of tannery processes, J Soc Leath Technol Chem, 83, 91

Graf D, 2000, The influence of the relative humidity of air during storage on the formation lowering of Cr(VI) in chrome tanned leathers, World Leather, 13, 38

10.1039/a707458a

Samitz M, 1960, Extraction by sweat of chromium from chrome tanned leathers, J Occup Environ Med, 2, 12

10.1111/j.0105-1873.2006.00802.x

10.1136/oem.51.6.371

10.1111/j.1600-0536.1983.tb04470.x

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Contact Dermatitis

Tập 72 Số 4

206-215

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