Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications

Acta Psychiatrica Scandinavica - Tập 112 Số 5 - Trang 330-350 - 2005
John Read1, Jim van Os2,3, Anthony P. Morrison4,5, Colin A. Ross6
1Department of Psychology, The University of Auckland, Auckland, New Zealand
2Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands
3Division of Psychological Medicine, Institute of Psychiatry, London
4Department of Psychology, University of Manchester, Manchester
5Psychology Services, Bolton Stafford and Trafford Mental Health Partnership, Manchester, UK
6Colin A. Ross Institute for Psychological Trauma, Richardson, TX, USA

Tóm tắt

Objective:  To review the research addressing the relationship of childhood trauma to psychosis and schizophrenia, and to discuss the theoretical and clinical implications.

Method:  Relevant studies and previous review papers were identified via computer literature searches.

Results:  Symptoms considered indicative of psychosis and schizophrenia, particularly hallucinations, are at least as strongly related to childhood abuse and neglect as many other mental health problems. Recent large‐scale general population studies indicate the relationship is a causal one, with a dose‐effect.

Conclusion:  Several psychological and biological mechanisms by which childhood trauma increases risk for psychosis merit attention. Integration of these different levels of analysis may stimulate a more genuinely integrated bio‐psycho‐social model of psychosis than currently prevails. Clinical implications include the need for staff training in asking about abuse and the need to offer appropriate psychosocial treatments to patients who have been abused or neglected as children. Prevention issues are also identified.

Từ khóa


Tài liệu tham khảo

Read J, 1997, Child abuse and psychosis: a literature review and implications for professional practice, Prof Psychol Res Pr, 28, 448, 10.1037/0735-7028.28.5.448

10.1192/bjp.184.5.416

10.1192/bjp.163.6.721

10.1111/j.1600-0447.1992.tb01458.x

10.1034/j.1600-0447.2003.00165.x

10.1097/00004583-199610000-00024

10.1034/j.1600-0447.2002.02303.x

10.1034/j.1399-5618.2000.020206.x

10.1001/archpsyc.57.10.953

10.1111/j.1600-0447.1995.tb09610.x

10.1176/ajp.144.11.1474

10.1097/00005053-199702000-00005

10.1192/bjp.186.2.121

10.1016/0165-1781(91)90107-Z

10.1176/ps.47.2.189

10.1016/S0145-2134(98)00009-X

10.1037/0735-7028.32.4.367

Rose S, 1991, Undetected abuse among intensive case management clients, Hosp Community Psychiatry, 42, 499

10.1097/00004583-198709000-00023

10.1016/S0006-3223(01)01239-2

10.1176/appi.ajp.161.8.1447

10.4324/9780203420393_chapter_16

10.1348/014466503322528892

10.1176/ajp.152.9.1322

10.1176/ajp.148.1.55

10.1016/0010-440X(93)90008-R

10.1080/00332747.1996.11024766

10.1176/appi.ajp.160.1.13

10.1016/0006-3223(95)00314-2

10.1023/A:1024794232175

Ross C, 2005, Schizophrenia: innovations in diagnosis and treatment

10.1001/archpsyc.1973.04200050100017

Muenzenmaier K, 2005, Comorbid PTSD and schizophrenia, Psychiatr Ann, 35, 51

10.1097/00005053-200004000-00004

10.1300/J229v04n01_04

Pivac N, 2004, Olanzapine versus fluphenazine in an open trial in patients with psychotic combat‐related posttraumatic stress disorder, Psychopharmacology, 175, 451

10.1016/0920-9964(95)00039-O

10.1097/00005053-200010000-00010

10.1093/oxfordjournals.aje.a112108

10.1007/BF00974158

10.1007/s00127-003-0596-5

10.1176/ps.47.5.531

Davidson J, 1999, Challenging silence: Innovative responses to sexual and domestic violence, 35

10.1176/ps.48.10.1273

10.1002/jts.2490090306

10.1016/S0145-2134(95)00137-9

10.1023/A:1024708916143

10.1037/h0079126

10.1348/14760830260569210

10.1007/BF00794947

10.1176/ajp.146.12.1602

10.1016/0010-440X(91)90009-2

Read J, 2005, Understanding trauma and psychosis

10.1007/BF01542090

Bryer J, 1987, Childhood sexual and physical abuse as factors in psychiatric illness, Am J Psychiatry, 44, 1426

10.1176/ajp.144.7.908

Craine L, 1988, Prevalence of a history of sexual abuse among female psychiatric patients in a state hospital system, Hosp Community Psychiatry, 39, 300

10.1176/ajp.145.9.1183-a

10.1007/BF00706957

10.1176/ajp.147.7.887

Jacobson A, 1990, The relevance of childhood sexual abuse to adult psychiatric inpatient care, Hosp Community Psychiatry, 41, 154

10.1176/ajp.147.2.214

10.1016/0145-2134(91)90028-C

10.1016/0010-440X(91)90086-R

10.1097/00005053-199206000-00009

10.1300/J070v01n01_05

10.1176/jnp.5.4.401

Muenzenmaier K, 1993, Childhood abuse and neglect among women outpatients with chronic mental illness, Hosp Community Psychiatry, 44, 666

10.1192/bjp.164.6.831

Ross C, 1994, Childhood abuse and positive symptoms of schizophrenia, Hosp Community Psychiatry, 45, 489

10.3109/00952999409106786

10.1515/IJAMH.1994.7.3.209

10.1037/h0079669

10.1111/j.1469-7610.1996.tb01495.x

Davies‐Netzley S, 1996, Childhood abuse as a precursor to homelessness for women with severe mental illness, Violence Victims, 11, 129, 10.1891/0886-6708.11.2.129

10.1176/ps.47.5.502

10.1016/0145-2134(96)00074-9

10.1037/0022-006X.66.3.493

10.1097/00005053-199901000-00006

10.1097/00004583-199904000-00010

10.1097/00005053-200006000-00005

10.1097/00005053-200108000-00006

10.1023/A:1013026318450

10.1016/S0887-6185(02)00097-X

10.1521/psyc.66.4.323.25446

10.1016/S0920-9964(02)00296-7

10.1016/S0145-2134(03)00139-X

10.1037/0021-843X.112.3.415

10.1016/j.drugalcdep.2004.05.005

10.1016/j.schres.2005.03.003

Schäfer I, Childhood trauma and dissociation in female patients with schizophrenia spectrum disorders, J Nerv Ment Dis

10.1111/j.1600-0447.2005.00623.x

Bowe S, The relationship between past childhood trauma and auditory hallucinations in individuals with psychosis, Br J Clin Psychol

10.1017/S0033291700036618

10.1192/bjp.165.5.675

10.1176/appi.ps.52.11.1485

10.1016/S0920-9964(03)00195-6

Lysaker P, Reported history of child sexual abuse in schizophrenia: associations with heightened symptom levels and poorer participation over four months in vocational rehabilitation, J Nerv Ment Dis

Fergusson D, 2000, Psychol Med, 529

10.1080/00050060108259653

Robins L, 1996, Deviant children growing up

10.1001/archpsyc.59.5.449

10.1037/0022-006X.70.1.246

10.1001/archpsyc.1995.03950240066012

10.1097/00004583-198705000-00023

Bentall R, 2003, Madness explained: psychosis and human nature

Read J, 2004, Models of madness: psychological, social and biological approaches to schizophrenia, 43, 10.4324/9780203420393_chapter_5

10.1046/j.0001-690X.2003.00217.x

10.1016/0010-440X(92)90052-R

10.1080/00332747.1999.11024849

10.1348/014466599162908

10.1093/oxfordjournals.schbul.a006985

10.1176/ps.50.11.1467

10.1097/00004583-199209000-00013

10.1097/00004583-199009000-00008

10.1097/00005053-199109000-00009

10.1097/00005053-199810000-00009

10.1192/bjp.182.6.543

10.1017/S1352465803003011

Ensink B, 1992, Confusing realities

10.1192/bjp.185.3.220

Ellenson G, 1985, Detecting a history of incest: a predictive syndrome, J Contemp Soc Work, 66, 525

10.3109/00048679009062913

10.1348/01446650360703357

10.1016/0165-1781(94)90075-2

Kahlbaum K, 1973, Catatonia

10.1037/0033-295X.111.4.984

10.1097/01.nmd.0000144693.12282.11

10.1037/0022-006X.72.1.121

Romme M, Understanding trauma and psychosis

10.3109/00048679709073822

10.1192/bjp.186.1.76

Read J, Mental health services and sexual abuse: the need for staff training, J Trauma Dissociation

10.1177/1524838002250760

Spauwen J, Impact of psychological trauma on the trajectory of psychosis liability, Br J Psychiatry

10.1097/01.nmd.0000092177.97317.26

10.1176/appi.books.9780890423349

10.1001/archpsyc.58.3.305

10.1097/00005053-199105000-00002

10.1023/A:1014331211311

10.1521/jaap.31.1.247.21938

Nurcombe B, 1996, Psychoses and pervasive developmental disorders in childhood and adolescence, 107

Tutkun H, 1998, Frequency of dissociative disorders among psychiatric inpatients in a Turkish university clinic, Am J Psychiatry, 155, 800

10.1097/00005053-199504000-00009

10.1016/j.comppsych.2004.07.032

10.1017/S1352465801003010

Bentall R, 2001, Persecutory delusions: a review and theoretical integration, Clin Psychol Rev, 22, 1

10.1017/S0033291701003312

10.1017/S1352465804001900

10.1016/S0272-7358(01)00103-9

10.1046/j.1365-2850.1998.00098.x

Chadwick P, 1994, The omnipotence of voices: a cognitive approach to auditory hallucinations, Br J Psychiatry, 164, 190, 10.1192/bjp.164.2.190

10.1016/j.brat.2003.08.009

10.1111/j.1600-0447.2005.00646.x

10.4324/9780203420393_chapter_20

10.4324/9780203493465

10.1016/j.psychres.2004.08.009

10.1002/jts.2490080402

Nadel L, 1996, The hippocampus: functions and clinical relevance, 455

10.1017/S1352465804001924

10.1097/01.nmd.0000105997.28152.4b

Moskowitz A, Dissociation and the dissociative disorders: DSM‐IV and beyond

10.1016/0010-440X(90)90014-J

10.1023/B:PSAQ.0000043510.41919.55

10.1037/0033-295X.104.4.667

10.1017/S0140525X99002046

10.1521/psyc.64.4.319.18602

10.1001/jama.284.5.592

Nemeroff C, 2004, Neurobiological consequences of childhood trauma, J Clin Psychiatry, 65, 18

Perry B, 1999, Splintered reflections, 9

10.1017/S0954579401003017

10.1034/j.1600-0447.2001.00237.x

Bremner J, 2002, Does stress damage the brain

Huiznick A, 2004, Prenatal stress and risk for psychopathology, Psychol Bull, 130, 115, 10.1037/0033-2909.130.1.115

10.1192/bjp.184.3.216

10.1016/S0074-7742(04)59006-2

10.1016/S0149-7634(03)00007-1

10.1017/S0140525X03000025

10.1017/S0033291702006785

10.1001/archpsyc.58.12.1137

10.1097/00001504-200411000-00010

10.1034/j.1600-0447.2000.00011.x

Rose S, 2005, The 21st century brain: exploring, mending and manipulating the mind

10.1034/j.1600-0447.2000.00304.x

Sham P, 1998, Statistics in human genetics

Van OS J, 2003, The epidemiology of schizophrenia, 235

10.1016/S0920-9964(98)00049-8

10.1176/appi.ajp.161.12.2312

10.1136/bmj.38267.664086.63

10.4324/9780203420393_chapter_23

10.1034/j.1600-0447.2000.00014.x

10.4324/9780203420393_chapter_21

10.4324/9780203420393_chapter_22

Kingdon D, 2004, Cognitive‐behavioural therapy of schizophrenia

10.1034/j.1600-0447.2000.00013.x

Martindale B, 2000, Psychosis: psychological approaches and their effectiveness

Mosher L, 2005, Soteria: through madness to deliverance

10.4324/9780203420393_chapter_15

10.1192/bjp.180.6.523

10.1073/pnas.2336126100

10.1093/schbul/23.4.685

Harris M, 1997, Sexual abuse in the lives of women diagnosed with serious mental illness

10.1176/appi.ps.52.11.1453

Shelley A, 2001, Symptom‐specific group therapy for inpatients with schizophrenia, Einstein Q, 18, 21

Herder D, 1991, The treatment of childhood sexual abuse in chronically mentally ill adults, Health Soc Work, 16, 50, 10.1093/hsw/16.1.50

Fowler D, 2000, Early interventions in psychosis, 112

10.1037/0735-7028.32.4.407

Lothian J, 2002, Asking about abuse during mental health assessments: clients’ views and experiences, N Z J Psychol, 31, 98

10.1176/ps.49.3.355

10.1016/S0145-2134(98)00121-5

10.1046/j.1440-0979.2002.00230.x

10.3109/00048679809062730

Cavanagh M‐R, 2004, Childhood abuse inquiry and response: a New Zealand training programme, N Z J Psychol, 33, 137

Knapp M, 2000, Schizophrenia costs and treatment cost‐effectiveness, Acta Psychiatr Scand, 102, 102

10.4324/9780203420393_chapter_18

10.1176/appi.ajp.160.9.1627

10.1016/j.chiabu.2005.01.004

10.4324/9780203420393