Childhood Sexual and Physical Abuse Histories, PTSD, Depression, and HIV Risk Outcomes in Women Injection Drug Users: A Potential Mediating Pathway

American Journal on Addictions - Tập 16 Số 6 - Trang 431-438 - 2007
Rosalyn E. Plotzker1, David S. Metzger2, William C. Holmes3,4
1Center for the Studies of Addiction, HIV Prevention Division, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
2Department of Psychiatry and Center for AIDS Research, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
3Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania
4Departments of Medicine and Epidemiology, Division of General Internal Medicine and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Tóm tắt

We explored links between childhood sexual abuse (CSA), childhood physical abuse (CPA), posttraumatic stress disorder (PTSD)/depression, and women injection drug users' (IDUs') risk in 113 women recruited from two syringe exchange sites. More than half (56%) reported CSA, 68% CPA, 23% likely were depressed‐only, and 53% likely had PTSD/depression. CSA was associated with sexual (p = 0.003) and drug risk (p = 0.05); CPA was not. CSA was associated with PTSD/depression (p = 0.03); PTSD/depression was associated with sexual (p < 0.01) and drug (p < 0.03) risk. After PTSD/depression adjustment, CSA was no longer associated with sexual or drug risk. These results suggest that women IDUs' CSA‐to‐risk path is mediated by PTSD/depression.

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