Childhood Obsessive–Compulsive Disorder: A Prospective Follow‐up Study

Journal of Child Psychology and Psychiatry and Allied Disciplines - Tập 31 Số 3 - Trang 363-380 - 1990
Martine F. Flament1, Elisabeth Koby2, Judith L. Rapoport2, Chantal van den Berg2, Theodore P. Zahn3, Christine E. Cox4, Martha B. Denckla5, Marge Lenane2
1Hôpital International de l'Université de Paris, Paris, France.
2Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, U.S.A.
3Laboratory of Psychology and Psychopathology, NIMH, Bethesda, MD 20892, U.S.A.
4Laboratory of Neuropsychology, National Institute of Neurological Disorders and Stroke, NIMH, Bethesda, MD 20892, U.S.A.
5Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD U.S.A.

Tóm tắt

Abstract Twenty‐five of 27 patients (93%) who had participated in a study of severe primary obsessive‐compulsive disorder with onset in childhood or adolescence, were seen 2–7 yrs after initial examination (mean, 4.4 yrs). They were compared to a group of normal controls matched for age, sex and IQ, and followed up for the same period. Continued psychopathology was striking for the patients, with only seven (28%), three males and four females, receiving no psychiatric diagnosis at follow‐up. Seventeen subjects (68%) still had obsessive‐compulsive disorder, 12 patients (48%) had another psychiatric disorder, most commonly anxiety and/or depression; neither initial response to clomipramine or any other baseline variable predicted outcome.

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Journal of Child Psychology and Psychiatry and Allied Disciplines

Tập 31 Số 3

363-380

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