Đặc trưng hóa sự tương tác giữa Protein LIM liên kết với Actinin (ALP) và miền que của α-actinin

Frank D, Kuhn C, Katus HA, Frey N: The sarcomeric Z-disc: a nodal point in signalling and disease. J Mol Med. 2006, 84 (6): 446-468. 10.1007/s00109-005-0033-1. Blanchard A, Ohanian V, Critchley D: The structure and function of alpha-actinin. J Muscle Res Cell Motil. 1989, 10 (4): 280-289. 10.1007/BF01758424. Broderick MJ, Winder SJ: Towards a complete atomic structure of spectrin family proteins. J Struct Biol. 2002, 137 (1–2): 184-193. 10.1006/jsbi.2002.4465. McKeown CR, Han HF, Beckerle MC: Molecular characterization of the Caenorhabditis elegans ALP/Enigma gene alp-1. Dev Dyn. 2006, 235 (2): 530-538. 10.1002/dvdy.20633. Xia H, Winokur ST, Kuo WL, Altherr MR, Bredt DS: Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs. J Cell Biol. 1997, 139 (2): 507-515. 10.1083/jcb.139.2.507. Faulkner G, Pallavicini A, Formentin E, Comelli A, Ievolella C, Trevisan S, Bortoletto G, Scannapieco P, Salamon M, Mouly V: ZASP: a new Z-band alternatively spliced PDZ-motif protein. J Cell Biol. 1999, 146 (2): 465-475. 10.1083/jcb.146.2.465. Guy PM, Kenny DA, Gill GN: The PDZ domain of the LIM protein enigma binds to beta-tropomyosin. Mol Biol Cell. 1999, 10 (6): 1973-1984. Pomies P, Macalma T, Beckerle MC: Purification and characterization of an alpha-actinin-binding PDZ-LIM protein that is Up-regulated during muscle differentiation. J Biol Chem. 1999, 274 (41): 29242-29250. 10.1074/jbc.274.41.29242. Zhou Q, Ruiz-Lozano P, Martone ME, Chen J: Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C. J Biol Chem. 1999, 274 (28): 19807-19813. 10.1074/jbc.274.28.19807. Nakagawa N, Hoshijima M, Oyasu M, Saito N, Tanizawa K, Kuroda S: ENH, containing PDZ and LIM domains, heart/skeletal muscle-specific protein, associates with cytoskeletal proteins through the PDZ domain. Biochem Biophys Res Commun. 2000, 272 (2): 505-512. 10.1006/bbrc.2000.2787. Passier R, Richardson JA, Olson EN: Oracle, a novel PDZ-LIM domain protein expressed in heart and skeletal muscle. Mech Dev. 2000, 92 (2): 277-284. 10.1016/S0925-4773(99)00330-5. Niederlander N, Fayein NA, Auffray C, Pomies P: Characterization of a new human isoform of the enigma homolog family specifically expressed in skeletal muscle. Biochem Biophys Res Commun. 2004, 325 (4): 1304-1311. 10.1016/j.bbrc.2004.10.178. Wang H, Harrison-Shostak DC, Lemasters JJ, Herman B: Cloning of a rat cDNA encoding a novel LIM domain protein with high homology to rat RIL. Gene. 1995, 165 (2): 267-271. 10.1016/0378-1119(95)00542-E. Kotaka M, Ngai SM, Garcia-Barcelo M, Tsui SK, Fung KP, Lee CY, Waye MM: Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1). J Cell Biochem. 1999, 72 (2): 279-285. 10.1002/(SICI)1097-4644(19990201)72:2<279::AID-JCB12>3.0.CO;2-7. Kotaka M, Kostin S, Ngai S, Chan K, Lau Y, Lee SM, Li H, Ng EK, Schaper J, Tsui SK: Interaction of hCLIM1, an enigma family protein, with alpha-actinin 2. J Cell Biochem. 2000, 78 (4): 558-565. 10.1002/1097-4644(20000915)78:4<558::AID-JCB5>3.0.CO;2-I. Vallenius T, Mäkelä TP: Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein. J Cell Sci. 2002, 115 (Pt 10): 2067-2073. Vallenius T, Scharm B, Vesikansa A, Luukko K, Schafer R, Mäkelä TP: The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of alpha-actinin with F-actin. Exp Cell Res. 2004, 293 (1): 117-128. 10.1016/j.yexcr.2003.09.004. Kiess M, Scharm B, Aguzzi A, Hajnal A, Klemenz R, Schwarte-Waldhoff I, Schafer R: Expression of ril, a novel LIM domain gene, is down-regulated in Hras-transformed cells and restored in phenotypic revertants. Oncogene. 1995, 10 (1): 61-68. Bashirova AA, Markelov ML, Shlykova TV, Levshenkova EV, Alibaeva RA, Frolova EI: The human RIL gene: mapping to human chromosome 5q31.1, genomic organization and alternative transcripts. Gene. 1998, 210 (2): 239-245. 10.1016/S0378-1119(98)00080-8. Torrado M, Senatorov VV, Trivedi R, Fariss RN, Tomarev SI: Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A. Invest Ophthalmol Vis Sci. 2004, 45 (11): 3955-3963. 10.1167/iovs.04-0721. Loughran G, Healy NC, Kiely PA, Huigsloot M, Kedersha NL, O'Connor R: Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth. Mol Biol Cell. 2005, 16 (4): 1811-1822. 10.1091/mbc.E04-12-1052. Pashmforoush M, Pomies P, Peterson KL, Kubalak S, Ross J, Hefti A, Aebi U, Beckerle MC, Chien KR: Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy. Nat Med. 2001, 7 (5): 591-597. 10.1038/87920. Zhou Q, Chu PH, Huang C, Cheng CF, Martone ME, Knoll G, Shelton GD, Evans S, Chen J: Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy. J Cell Biol. 2001, 155 (4): 605-612. 10.1083/jcb.200107092. Jani K, Schöck F: Zasp is required for the assembly of functional integrin adhesion sites. J Cell Biol. 2007, 179 (7): 1583-1597. 10.1083/jcb.200707045. Schulz TW, Nakagawa T, Licznerski P, Pawlak V, Kolleker A, Rozov A, Kim J, Dittgen T, Kohr G, Sheng M: Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL. J Neurosci. 2004, 24 (39): 8584-8594. 10.1523/JNEUROSCI.2100-04.2004. Au Y, Atkinson RA, Guerrini R, Kelly G, Joseph C, Martin SR, Muskett FW, Pallavicini A, Faulkner G, Pastore A: Solution structure of ZASP PDZ domain; implications for sarcomere ultrastructure and enigma family redundancy. Structure (Camb). 2004, 12 (4): 611-622. 10.1016/j.str.2004.02.019. Klaavuniemi T, Kelloniemi A, Ylänne J: The ZASP-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin rod and for targeting to the muscle Z-line. J Biol Chem. 2004, 279 (25): 26402-26410. 10.1074/jbc.M401871200. Bauer K, Kratzer M, Otte M, de Quintana KL, Hagmann J, Arnold GJ, Eckerskorn C, Lottspeich F, Siess W: Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells. Blood. 2000, 96 (13): 4236-4245. Klaavuniemi T, Ylänne J: Zasp/Cypher internal ZM-motif containing fragments are sufficient to co-localize with alpha-actinin – analysis of patient mutations. Exp Cell Res. 2006, 312 (8): 1299-1311. 10.1016/j.yexcr.2005.12.036. Vatta M, Mohapatra B, Jimenez S, Sanchez X, Faulkner G, Perles Z, Sinagra G, Lin JH, Vu TM, Zhou Q: Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction. J Am Coll Cardiol. 2003, 42 (11): 2014-2027. 10.1016/j.jacc.2003.10.021. Selcen D, Engel AG: Mutations in ZASP define a novel form of muscular dystrophy in humans. Ann Neurol. 2005, 57 (2): 269-276. 10.1002/ana.20376. Te Velthuis AJ, Isogai T, Gerrits L, Bagowski CP: Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motif. PLoS ONE. 2007, 2 (2): e189-10.1371/journal.pone.0000189. Prilusky J, Felder CE, Zeev-Ben-Mordehai T, Rydberg EH, Man O, Beckmann JS, Silman I, Sussman JL: FoldIndex(C): a simple tool to predict whether a given protein sequence is intrinsically unfolded. Bioinformatics. 2005, 21 (16): 3435-3438. 10.1093/bioinformatics/bti537. Schultz J, Milpetz F, Bork P, Ponting CP: SMART, a simplemodular architecture research tool: identification of signaling domains. Proc Natl Acad Sci USA. 1998, 95 (11): 5857-5864. 10.1073/pnas.95.11.5857. Linding R, Jensen LJ, Diella F, Bork P, Gibson TJ, Russell RB: Protein disorder prediction: implications for structural proteomics. Structure (Camb). 2003, 11 (11): 1453-1459. 10.1016/j.str.2003.10.002. Bondos SE, Bicknell A: Detection and prevention of protein aggregation before, during, and after purification. Anal Biochem. 2003, 316 (2): 223-231. 10.1016/S0003-2697(03)00059-9. Golovanov AP, Hautbergue GM, Wilson SA, Lian LY: A simple method for improving protein solubility and long-term stability. J Am Chem Soc. 2004, 126 (29): 8933-8939. 10.1021/ja049297h. Alho N, Klaavuniemi T, Ylänne J, Permi P, Mattila S: Backbone NMR assignment of the internal interaction site of ALP. Biomolecular NMR Assignments. 2007, 1 (1): 85-10.1007/s12104-007-9024-1. Spera S, Bax A: Empirical correlation between protein backbone conformation and Calpha and Cbeta 13-C nuclear magnetic resonance chemical shifts. J Am Chem Soc. 1991, 113: 5490-5492. 10.1021/ja00014a071. Small JV: Structure-function relationships in smooth muscle: the missing links. BioEssays. 1995, 17 (9): 785-792. 10.1002/bies.950170908. Vlahos CJ, McDowell SA, Clerk A: Kinases as therapeutic targets for heart failure. Nat Rev Drug Discov. 2003, 2 (2): 99-113. 10.1038/nrd1009. Wilkins BJ, Molkentin JD: Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun. 2004, 322 (4): 1178-1191. 10.1016/j.bbrc.2004.07.121. Vega RB, Bassel-Duby R, Olson EN: Control of cardiac growth and function by calcineurin signaling. J Biol Chem. 2003, 278 (39): 36981-36984. 10.1074/jbc.R300023200. Kuroda S, Tokunaga C, Kiyohara Y, Higuchi O, Konishi H, Mizuno K, Gill GN, Kikkawa U: Protein-protein interaction of zinc finger LIM domains with protein kinase C. J Biol Chem. 1996, 271 (49): 31029-31032. 10.1074/jbc.271.49.31029. Frey N, Olson EN: Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins. J Biol Chem. 2002, 277 (16): 13998-14004. 10.1074/jbc.M200712200. Djinovic-Carugo K, Young P, Gautel M, Saraste M: Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments. Cell. 1999, 98 (4): 537-546. 10.1016/S0092-8674(00)81981-9. Ylänne J, Scheffzek K, Young P, Saraste M: Crystal Structure of the alpha-Actinin Rod Reveals an Extensive Torsional Twist. Structure. 2001, 9 (7): 597-604. 10.1016/S0969-2126(01)00619-0. Hotulainen P, Lappalainen P: Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J Cell Biol. 2006, 173 (3): 383-394. 10.1083/jcb.200511093. Sambrook J, Russell DW: Molecular Cloning, a laboratory mamual. 2001, New York: Cold Spring Harbor Laboratory Press, 3