Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

Immunological Reviews - Tập 74 Số 1 - Trang 29-56 - 1983
Deno P. Dialynas1, D B Wilde1, Philippa Marrack2, A Pierres3, Katherine A. Wall1, Wendy L. Havran1, Gillis R. Otten1, Michael R. Loken1, Michel Pierres3, John W. Kappler2, Frank W. Fitch2
1Department of Microbiology The University of Chicago, Chicago, Illinois, U.S.A.
2National Jewish Hospital and Research Center, University of Colorado Health Sciences Center, Denver, Colorado, U.S.A.
3Centre d'Immunologie INSERM-CNRS de Marseille-Luminy, 13288 Marseille, Cedex 9, France

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10.1084/jem.156.4.1065

Borst J., 1982, Complexity of the human T lymphocytespecific cell surface antigen T3, J. Immunol., 128, 1560, 10.4049/jimmunol.128.4.1560

10.1084/jem.141.6.1390

Cerottini J.‐C., 1981, Limiting dilution analysis of alloantigen‐reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H‐2 alloantigens, J. Immunol., 126, 490, 10.4049/jimmunol.126.2.490

10.1016/0022-1759(75)90026-5

Davignon D., 1981, Monoclonal antibody to a novel lymphocyte function‐associated antigen (LFA‐I): Mechanism of blockade of T lymphocyte‐mediated killing and effects on other T and B lymphocyte functions, J. Immunol., 127, 590, 10.4049/jimmunol.127.2.590

10.1084/jem.153.3.595

10.1007/978-1-4684-8959-0_33

Dialynas D. P. Quan Z. S. Wail K. A. Pierres A. Quintans J. Loken M. R. Pierres M.&Fitch F. W.(1983) Characterization of the murine T cell surface molecule designated L3T4 identified by monoclonal antibody GKI.5: Similarity of L3T4 to the human Leu3/T4 molecule and the possible involvement of L3T4 in class II MHC antigenreactivity. (Submitted for publication).

Ely J. M., 1981, Alloreactive cloned T cell lines. V. Differential kinetics of IL‐2, CSF, and BCSF release by a cloned T amplifier cell and its variant, J. Immunol., 127, 2345, 10.4049/jimmunol.127.6.2345

10.1084/jem.154.1.193

Engleman E. G., 1981, Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens., J. Immunol., 127, 2124, 10.4049/jimmunol.127.5.2124

10.1073/pnas.78.1.544

Fan J., 1980, Studies on the induction and expression of T cell‐mediated immunity. X. Inhibition by Lyt‐2,3 antisera of cytotoxic T lymphocyte mediated antigen‐specific and ‐nonspecific cytotoxicity: Evidence for the blocking of the binding between T lymphocytes and target cells not the post‐binding cytolytic steps, J. Immunol, 125, 2444, 10.4049/jimmunol.125.6.2444

Farrar J. J., 1980, Thymoma production of T cell growth factor (Interieukin 2), J. Immunol., 125, 2555, 10.4049/jimmunol.125.6.2555

Fitch F. W., 1982, Interleukins. Lymphokines, and Cytokines

10.4049/jimmunol.120.6.2027

10.1084/jem.151.4.876

10.1111/j.1600-065X.1981.tb00439.x

10.1111/j.1600-065X.1982.tb01058.x

10.1084/jem.157.4.1149

10.1007/BF00343313

10.1084/jem.153.5.1198

10.1084/jem.156.5.1366

10.1038/256495a0

Krensky A. M., 1982, Specificity of OKT4+ cytotoxic T lymphocyte clones., J. Immunol., 129, 10.4049/jimmunol.129.5.2001

10.1084/jem.156.1.41

10.1126/science.314668

Kurzinger K., 1981, A novel lymphocyte function‐associated antigen (LFA‐1): cellular distribution, quantitative expression, and structure, J. Immunol., 127, 596, 10.4049/jimmunol.127.2.596

10.1084/jem.157.3.921

Lancki D. W. Vogel S. N. Beller D. L.Prystowsky M. B. Dialynas D. P. Wall K. A.&Fitch F. W.(1983b) Using monoclonal antibodies directed against cell surface proteins to characterize both antigen‐specific and Con A‐mediated release of lymphokines from both class I and class II MHC antigen‐reactive cloned murine T cell lines. (Manuscript in preparation).

10.1084/jem.152.2.280

10.1084/jem.153.2.310

10.1111/j.1600-065X.1979.tb00289.x

Loken M. R., 1979, Flow Cytometry and Sorting, 505

10.1002/eji.1830110911

10.1111/j.1600-065X.1982.tb01061.x

10.1084/jem.156.6.1711

Marrack P., 1983, Binding of antigen‐specific, H‐2‐restricted T cell hybridomas to antigen pulsed adherent cell monolayers, J. Immunol., 130, 2088, 10.4049/jimmunol.130.5.2088

10.1038/297628a0

10.1111/j.1600-065X.1979.tb00290.x

10.1126/science.6981845

10.1073/pnas.79.14.4395

Miller R. A., 1982, Enumeration of lL‐2‐secreting helper T cells by limiting dilution analysis, and demonstration of unexpectedly high levels of IL‐2 production per responding cell, J. Immunol., 128, 2258, 10.4049/jimmunol.128.5.2258

Okada M, 1980, The differentiation of cytotoxic T cells in vitro. II. Amplifying factor(s) produced in primary mixed lymphocyte cultures against K / D stimuli require the presence of Lyt‐2+ cells but not Lyt‐T cells, J. Immunol., 125, 300, 10.4049/jimmunol.125.1.300

10.1111/j.1365-3083.1982.tb00691.x

Pierres A., 1983, Clonal analysis of B and T cell responses to la antigens. IV. Proliferative T cell clones recognizing Eβ and/or Eα allodeterminants, J. Immunol., 130, 1262, 10.4049/jimmunol.130.3.1262

10.1007/BF00350120

10.1002/eji.1830120112

10.1016/0167-5699(83)90094-4

10.1073/pnas.79.23.7489

Sarmiento M., 1980, IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt‐2 antigen block T cell‐mediated cytolysis in the absence of complement, J. Immunol., 125, 2665, 10.4049/jimmunol.125.6.2665

10.1089/hyb.1.1981.1.13

10.1111/j.1600-065X.1982.tb01063.x

Spits H., 1982, The role of T cell differentiation markers in antigen‐specific and lectin‐dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens, J. Immunol., 129, 1563, 10.4049/jimmunol.129.4.1563

10.1073/pnas.78.11.7101

10.1002/eji.1830110304

10.1084/jem.157.2.720

Teh H.‐S., 1980, The use of a clonal assay for cytotoxic T lymphocytes to determine the Ly phenotypes of cytotoxic precursor and effector cells to alloantigens and trinitrophenyl‐modified self antigens., J. Immunol., 125

10.1084/jem.154.5.1517

10.1002/eji.1830110105

Wall K. A., 1983, Inhibition of proliferation of Mls and la‐reactive cloned T cells by a monoclonal antibody against a determinant shared by I‐A and I‐E., J. Immunol.

10.1084/jem.154.6.1970

10.1084/jem.147.5.1395

White J., 1983, Use of I region‐restricted, antigen‐specific T cell hybridomas to produce idiotypically specific anti‐receptor antibodies, J. Immunol., 130, 1033, 10.4049/jimmunol.130.3.1033

Wilde D. B. Marrack P. Kappler J. W. Dialynas D. P.&Fitch F. W.(1983) Evidence implicating L3T4in class II MHC antigen‐reactivity: Monoclonal antibody GK 1.5 (anti‐ L3T4a) blocks class II MHC antigen‐specific proliferation release of lymphokines and binding by cloned murine helper T lymphocyte lines. (Submitted for publication).

Wilde D. B. Prystowsky M. B. Belier DL Goldwasser E. Ihle J. N. Vogel S. N.&Filch F. W.(1983b) Comparison of altogeneic and self‐restricted stimulation of lymphokine production by cloned T cells with dual antigenic reactivity. (Submitted for publication).