Characterization of Three Plasmid Deoxyribonucleic Acid Molecules in a Strain of Streptococcus faecalis : Identification of a Plasmid Determining Erythromycin Resistance

Journal of Bacteriology - Tập 117 Số 1 - Trang 283-289 - 1974
Don B. Clewell1, Yoshihiko Yagi1, Gary M. Dunny1, SAMUEL SCHULTZ1
1Dental Research Institute, Departments of Oral Biology and Microbiology, Schools of Dentistry and Medicine, The University of Michigan, Ann Arbor, Michigan 48104

Tóm tắt

Three plasmids designated α, β, and γ, distinguishable by their molecular weights (6, 17, and 34 million, respectively) were isolated from Streptococcus faecalis strain DS-5 (ATCC 14508). Derivatives of this strain “cured” for erythromycin resistance lacked the β-plasmid. In the parent strain the β-plasmid was estimated to be present to the extent of one to two copies per chromosomal genome equivalent whereas the α- and γ-plasmids were about nine and five copies, respectively.

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Tài liệu tham khảo

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Thông tin xuất bản

Journal of Bacteriology

Tập 117 Số 1

283-289

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