Categorization of humans in biomedical research: genes, race and disease

Genome Biology - 2002
Neil Risch1,2, Esteban Burchard3, Elad Ziv3, Hua Tang4
1Division of Research, Kaiser Permanente, Oakland, USA
2Department of Genetics Stanford University School of Medicine Stanford, USA
3Department of Medicine, University of California, San Francisco, USA
4Department of Statistics, Stanford University, Stanford, USA

Tóm tắt

A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. Some claim 'no biological basis for race' while others advocate a 'race-neutral' approach, using genetic clustering rather than self-identified ethnicity for human genetic categorization. We provide an epidemiologic perspective on the issue of human categorization in biomedical and genetic research that strongly supports the continued use of self-identified race and ethnicity.

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