Cardiovascular disease and Alzheimer's disease: common links

Journal of Internal Medicine - Tập 260 Số 3 - Trang 211-223 - 2006
Meir J. Stampfer1
1Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115 USA

Tóm tắt

Abstract.

Growing evidence supports a strong and likely causal association between cardiovascular disease (CVD), and its risk factors, with incidence of cognitive decline and Alzheimer's disease. Individuals with subclinical CVD are at higher risk for dementia and Alzheimer's. Several cardiovascular risk factors are also risk factors for dementia, including hypertension, high LDL cholesterol, low HDL cholesterol and especially diabetes. Moderate alcohol appears to be protective for both CVD and dementia. In contrast, inflammatory markers predict cardiovascular risk, but not dementia, despite biological plausibility for such a link. The substantial overlap in risk factors points to new avenues for research and prevention.

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Journal of Internal Medicine

Tập 260 Số 3

211-223

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