Cardioprotective effects of Ferulic acid against various drugs and toxic agents

Vater LB, Lefebvre B, Turk A, Clasen SC (2022) Fluoropyrimidine cardiotoxicity: Incidence, outcomes, and safety of rechallenge. Curr Oncol Rep. https://doi.org/10.1007/s11912-022-01256-6 Leong Bin Abdullah MFI, Singh D (2021) The adverse cardiovascular effects and cardiotoxicity of Kratom (Mitragyna speciosa Korth.): a comprehensive review. Front Pharmacol 27;12:726003. Bhagat A, Kleinerman ES (2020) Anthracycline-Induced cardiotoxicity: causes, mechanisms, and prevention. Adv Exp Med Biol 1257:181–192 Pistillucci G, Ciorra AA, Sciacca V, Raponi M, Rossi R, Veltri E (2015) Troponina I e Peptide Natriuretico Cerebrale (BNP) come biomarcatori predittivi di cardiotossicità nelle pazienti affette da carcinoma della mammella in terapia adiuvante con antracicline e trastuzumab [Troponin I and B-type Natriuretic Peptide (BNP) as biomarkers for the prediction of cardiotoxicity in patients with breast cancer treated with adjuvant anthracyclines and trastuzumab]. Clin Ter 166(1):e67–71. Italian. Patel VG, Cornell RF (2019) Cardiovascular complications associated with multiple myeloma therapies: incidence, pathophysiology, and management. Curr Oncol Rep 21(4):29 Nicol M, Baudet M, Cohen-Solal A (2019) Subclinical left ventricular dysfunction during chemotherapy. Card Fail Rev 5(1):31–36 Ma W, Wei S, Zhang B, Li W (2020) Molecular mechanisms of cardiomyocyte death in drug-induced cardiotoxicity. Front Cell Dev Biol 3(8):434 Ganesan K, Jayachandran M, Xu B (2020) Diet-derived phytochemicals targeting colon cancer stem cells and microbiota in colorectal cancer. Int J Mol Sci 21(11):3976 Zhu F, Du B, Xu B (2018) Anti-inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: a review. Crit Rev Food Sci Nutr 58(8):1260–1270 Strzępek-Gomółka M, Gaweł-Bęben K, Kukula-Koch W (2021) Achillea species as sources of active phytochemicals for dermatological and cosmetic applications. Oxid Med Cell Longev 25(2021):6643827 Balakrishnan R, Azam S, Cho DY, Su-Kim I, Choi DK (2021) Natural phytochemicals as novel therapeutic strategies to prevent and treat parkinson’s disease: current knowledge and future perspectives. Oxid Med Cell Longev 25:6680935 Xu DP, Li HB (2015) Antioxidant phytochemicals for the prevention and treatment of chronic diseases. Molecules 20(12):21138–21156 Lyu JI, Ryu J, Jin CH, Kim DG, Kim JM, Seo KS et al (2020) Phenolic compounds in extracts of Hibiscus acetosella (Cranberry Hibiscus) and their antioxidant and antibacterial properties. Molecules 25(18):4190 Dudonné S, Dal-Pan A, Dubé P, Varin TV, Calon F, Desjardins Y (2016) Potentiation of the bioavailability of blueberry phenolic compounds by co-ingested grape phenolic compounds in mice, revealed by targeted metabolomic profiling in plasma and feces. Food Funct 7(8):3421–3430 Kumar N, Pruthi V (2014) Potential applications of ferulic acid from natural sources. Biotechnol Rep (Amst) 16(4):86–93 Zhao J, Gao J, Li H (2020) Ferulic acid confers protection on islet β cells and placental tissues of rats with gestational diabetes mellitus. Cell Mol Biol (Noisy-le-grand) 66(1):37–41 Senthil Kumar C, Thangam R, Mary SA, Kannan PR, Arun G, Madhan B (2020) Targeted delivery and apoptosis induction of trans-resveratrol-ferulic acid loaded chitosan coated folic acid conjugate solid lipid nanoparticles in colon cancer cells. Carbohydr Polym 1(231):115682 Kelainy EG, Ibrahim Laila IM, Ibrahim SR (2019) The effect of ferulic acid against lead-induced oxidative stress and DNA damage in kidney and testes of rats. Environ Sci Pollut Res Int 26(31):31675–31684 Roghani M, Kalantari H, Khodayar MJ, Khorsandi L, Kalantar M, Goudarzi M, Kalantar H (2020) Alleviation of liver dysfunction, oxidative stress and inflammation underlies the protective effect of ferulic acid in methotrexate-induced hepatotoxicity. Drug Des Devel Ther 20(14):1933–1941 Mancuso C, Santangelo R (2014) Ferulic acid: pharmacological and toxicological aspects. Food Chem Toxicol 65:185–195 Turkez H, Arslan ME, Barboza JN, Kahraman CY, de Sousa DP, Mardinoğlu A (2021) Therapeutic potential of ferulic acid in Alzheimer’s disease. Curr Drug Deliv. https://doi.org/10.2174/1567201819666211228153801 Graf E (1992) Antioxidant potential of ferulic acid. Free Radic Biol Med 13:435–448 Zhao Z, Moghadasian MH (2008) Chemistry, natural sources, dietary intake and pharmacokinetic properties of ferulic acid: a review. Food Chem 109:691–702 Sakakibara H, Honda Y, Nakagawa S, Ashida H, Kanazawa K (2002) Simultaneous determination of all polyphenols in vegetables, fruits, and teas. J Agric Food Chem 51:571–581 Adom KK, Liu RH (2002) Antioxidant activity of grains. J Agric Food Chem 50:6182–6187 Li D, Rui YX, Guo SD, Luan F, Liu R, Zeng N (2021) Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives. Life Sci 1(284):119921 Graf E (1992) Antioxidant potential of ferulic acid. Free Radic Biol Med 13(4):435–448 Zhao Z, Egashira Y, Sanada H (2004) Ferulic acid is quickly absorbed from rat stomach as the free form and then conjugated mainly in liver. J Nutr 134(11):3083–3088 Wolffram S, Weber T, Grenacher B, Scharrer E (1995) A Na(+)-dependent mechanism is involved in mucosal uptake of cinnamic acid across the jejunal brush border in rats. J Nutr 125(5):1300–1308 Spencer JP, Chowrimootoo G, Choudhury R, Debnam ES, Srai SK, Rice-Evans C (1999) The small intestine can both absorb and glucuronidate luminal flavonoids. FEBS Lett 458(2):224–230 Zhao Z, Moghadasian MH (2008) Chemistry, natural sources, dietary intake and pharmacokinetic properties of ferulic acid: a review. Food Chem 109(4):691–702 Rondini L, Peyrat-Maillard MN, Marsset-Baglieri A, Berset C (2002) Sulfated ferulic acid is the main in vivo metabolite found after short-term ingestion of free ferulic acid in rats. J Agric Food Chem 50(10):3037–3041 Srinivasan M, Sudheer AR, Menon VP (2007) Ferulic Acid: therapeutic potential through its antioxidant property. J Clin Biochem Nutr 40(2):92–100 Higashida H, Egorova A, Higashida C, Zhong ZG, Yokoyama S, Noda M, Zhang JS et al (1999) Sympathetic potentiation of cyclic ADP-ribose formation in rat cardiac myocytes. J Biol Chem 274(47):33348–33354 Ng SP, Nomura W, Mohri S, Takahashi H, Jheng HF, Ara T et al (2019) Soy hydrolysate enhances the isoproterenol-stimulated lipolytic pathway through an increase in β-adrenergic receptor expression in adipocytes. Biosci Biotechnol Biochem 83(9):1782–1789 Steen EM, Noronha-Dutra AA, Woolf N (1982) The response of isolated rat heart cells to cardiotoxic concentrations of isoprenaline. J Pathol 137(2):167–176 Yogeeta SK, Gnanapragasam A, Kumar SS, Subhashini R, Sathivel A, Devaki T (2006) Synergistic interactions of ferulic acid with ascorbic acid: its cardioprotective role during isoproterenol induced myocardial infarction in rats. Mol Cell Biochem 283(1–2):139–146 Yogeeta SK, Hanumantra RB, Gnanapragasam A, Senthilkumar S, Subhashini R, Devaki T (2006) Attenuation of abnormalities in the lipid metabolism during experimental myocardial infarction induced by isoproterenol in rats: beneficial effect of ferulic acid and ascorbic acid. Basic Clin Pharmacol Toxicol 98(5):467–472 Yogeeta SK, Raghavendran HR, Gnanapragasam A, Subhashini R, Devaki T (2006) Ferulic acid with ascorbic acid synergistically extenuates the mitochondrial dysfunction during beta-adrenergic catecholamine induced cardiotoxicity in rats. Chem Biol Interact 163(1–2):160–169 Yogeeta SK, Gnanapragasam A, Senthilkumar S, Subhashini R, Devaki T (2006) Synergistic salubrious effect of ferulic acid and ascorbic acid on membrane-bound phosphatases and lysosomal hydrolases during experimental myocardial infarction in rats. Life Sci 80(3):258–263 Jain PG, Mahajan UB, Shinde SD, Surana SJ (2018) Cardioprotective role of FA against isoproterenol induced cardiac toxicity. Mol Biol Rep 45(5):1357–1365 Zhang XJ, Cui ZH, Zhao YX, He TT, Wang L, Liang XW (2021) Ferulic acid ameliorates isoproterenol-induced heart failure by decreasing oxidative stress and inhibiting cardiocyte apoptosis via activating Nrf2 signaling pathway in rats. Biol Pharm Bull 44(3):396–403 Tacar O, Sriamornsak P, Dass CR (2013) Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J Pharm Pharmacol 65(2):157–170 Chaterjee K, Jianqing Z, Norman H, Joel SK (2010) Doxorubicin cardiomyopathy. Cardiology 115(2):155–162 Aswar U, Mahajan U, Kandhare A, Aswar M (2019) Ferulic acid ameliorates doxorubicin-induced cardiac toxicity in rats. Naunyn Schmiedebergs Arch Pharmacol 392(6):659–668 Shulman LN (1993) The biology of alkylating-agent cellular injury. Hematol Oncol Clin North Am 7(2):325–335 Ahlmann M, Hempel G (2016) The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy. Cancer Chemother Pharmacol 78(4):661–671 Iqubal A, Iqubal MK, Sharma S, Ansari MA, Najmi AK, Ali SM (2019) Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: old drug with a new vision. Life Sci 1(218):112–131 Song Y, Zhang C, Wang C, Zhao L, Wang Z, Dai Z, Lin S, Kang H, Ma X (2016) Ferulic acid against cyclophosphamide-induced heart toxicity in mice by inhibiting NF-κB pathway. Evid Based Complement Alternat Med 2016:1261270 Vineetha VP, Raghu KG (2019) An overview on arsenic trioxide-induced cardiotoxicity. Cardiovasc Toxicol 19(2):105–119 Panneerselvam L, Raghunath A, Ravi MS, Vetrivel A, Subramaniam V, Sundarraj K, Perumal E (2020) Ferulic acid attenuates arsenic-induced cardiotoxicity in rats. Biotechnol Appl Biochem 67(2):186–195 Perumal E, Eswaran S, Parvin R, Balasubramanian S (2021) Mitigation of arsenic induced developmental cardiotoxicity by ferulic acid in zebrafish. Comp Biochem Physiol C Toxicol Pharmacol 244:109021 Furman BL (2015) Streptozotocin-induced diabetic models in mice and rats. Curr Protoc Pharmacol 70:5.47.1–5.47.20. Chowdhury S, Ghosh S, Rashid K, Sil PC (2016) Deciphering the role of ferulic acid against streptozotocin-induced cellular stress in the cardiac tissue of diabetic rats. Food Chem Toxicol 97:187–198 Bohlen HG (2015) Nitric oxide and the cardiovascular system. Compr Physiol 5(2):808–823 Mahmoody SA, Gharakhanlou R, Roshan VD, Hedayati M (2013) Individual and concomitant effects of cardioprotective programs on cardiac apelinergic system and oxidative state in L-NAME-induced hypertension. Clin Exp Hypertens 35(1):20–27 Alam MA, Sernia C, Brown L (2013) Ferulic acid improves cardiovascular and kidney structure and function in hypertensive rats. J Cardiovasc Pharmacol 61(3):240–249 Gordon RY, Mugantseva EA, Khutzian SS, Podolski IY (2009) Cycloheximide-induced inhibition of protein synthesis in hippocampal pyramidal neurons is time-dependent: differences between CA1 and CA3 areas. Neurosci Lett 461(3):249–251 Horiuchi T, Mitoma H, Harashima S, Tsukamoto H, Shimoda T (2010) Transmembrane TNF-alpha: structure, function and interaction with anti-TNF agents. Rheumatology (Oxford) 49(7):1215–1228 Zelová H, Hošek (2013) TNF-α signalling and inflammation: interactions between old acquaintances. Inflamm Res 62(7):641–651 Li C, Chen L, Song M, Fang Z, Zhang L, Coffie JW et al (2020) Ferulic acid protects cardiomyocytes from TNF-α/cycloheximide-induced apoptosis by regulating autophagy. Arch Pharm Res 43(8):863–874 Sun S, Ruan Y, Yan M, Xu K, Yang Y, Shen T, Jin Z (2021) Ferulic acid alleviates oxidative stress-induced cardiomyocyte injury by the regulation of miR-499-5p/p21 signal cascade. Evid Based Complement Alternat Med 7(2021):1921457 Bumrungpert A, Lilitchan S, Tuntipopipat S, Tirawanchai N, Komindr S (2018) Ferulic acid supplementation improves lipid profiles, oxidative stress, and inflammatory status in hyperlipidemic subjects: a randomized, double-blind. Placebo-Control Clin Trial Nutr 10(6):713 Waibel JS, Mi QS, Ozog D, Qu L, Zhou L, Rudnick A, Al-Niaimi F, Woodward J, Campos V, Mordon S (2016) Laser-assisted delivery of vitamin C, vitamin E, and ferulic acid formula serum decreases fractional laser postoperative recovery by increased beta fibroblast growth factor expression. Lasers Surg Med 48(3):238–244 Wu Y, Zheng X, Xu XG, Li YH, Wang B, Gao XH, Chen HD, Yatskayer M, Oresajo C (2013) Protective effects of a topical antioxidant complex containing vitamins C and E and ferulic acid against ultraviolet irradiation-induced photodamage in Chinese women. J Drugs Dermatol 12(4):464–468 Xu J, Li YK, Liang ZJ (1992) Effects of tetramethylpyrazine and ferulic acid alone or combined on vascular smooth muscle, blood viscosity and toxicity. Zhongguo Zhong Yao Za Zhi 17(11):680–2, 703–704 Peng CC, Hsieh CL, Wang HE, Chung JY, Chen KC, Peng RY (2012) Ferulic acid is nephrodamaging while gallic acid is renal protective in long term treatment of chronic kidney disease. Clin Nutr 31(3):405–414 Choi JH, Park JK, Kim KM, Lee HJ, Kim S (2018) In vitro and in vivo antithrombotic and cytotoxicity effects of ferulic acid. J Biochem Mol Toxicol 32(1):e22004 Truzzi F, Valerii MC, Tibaldi C, Zhang Y, Abduazizova V, Spisni E, Dinelli G (2020) Are supplements safe? Effects of gallic and ferulic acids on in vitro cell models. Nutrients 12(6):1591