CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Nature Medicine - Tập 19 Số 10 - Trang 1264-1272 - 2013
Stephanie M. Pyonteck1, Leila Akkari1, Alberto J. Schuhmacher1, Robert L. Bowman1, Lisa Sevenich1, Daniela F. Quail1, Oakley C. Olson1, Marsha L. Quick1, Jason T. Huse2, Virginia Teijeiro1, Manu Setty3, Christina Leslie3, Yoko Oei4, Alicia Pedraza2, Jianan Zhang2, Cameron Brennan5, James Sutton4, Eric C. Holland5, Dylan Daniel4, Johanna A. Joyce5
1Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York, USA
2Human Oncology and Pathogenesis Program, MSKCC, New York, New York, USA
3Computational Biology, MSKCC, New York, New York, USA
4Novartis Institutes for Biomedical Research, Emeryville, California, USA
5Brain Tumor Center, MSKCC, New York, New York, USA

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