Brazilian baccharis toxins: Livestock poisoning and the isolation of macrocyclic trichothecene glucosides

Wiley - Tập 4 Số 2 - Trang 58-71 - 1996
Bruce B. Jarvis1, Shengjun Wang1, Christopher Cox1, M. Madhusudana Rao2, V. Balakrishnan R. Philip2, Mary Suzan Varaschin3, Cláudio S.L. Barros3
1Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland
2Texas Veterinary Medical Diagnostic Laboratory, Texas A&M University, College Station, Texas
3Departamento de Patologia, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.

Tóm tắt

AbstractSamples of the toxic Brazilian plant, Baccharis coridifolia, which is reponsible for numerous cases of livestock poisoning in southern Brazil and Argentina, were collected during the growing season, and the toxicities in calves of the plant materials were correlated with the levels of macrocyclic trichothecenes present. Female plants in flower were considerably more toxic than male plants or plants not in flower. Plants not in flower were of intermediate toxicity The female plants in flower typically contained 5–10 times the levels of toxins as were found in the male plants. In addition, six new glucosides of the macrocyclic trichothecenes were isolated and characterized. The most prominent glucosides, those of roridins A and E, were found in high levels in the female plants.

Từ khóa


Tài liệu tham khảo

Aboul‐NasrMB(1989):Studies on Baccharis coridifolia—Myrothecium species interaction. Ph.D. thesis. University of Maryland College Park MD.

10.1007/BF00396694

Chakrabarti DK, 1986, Occurrence of free and conjugated 12, 13‐epoxytrichothecenes and zearalenone in banana fruits infected with Fusarium monilliforme., Appl Environ Microbiol, 51, 217, 10.1128/aem.51.1.217-219.1986

Costa ER, 1995, Intoxicação experimental por Baccharis coridifolia (Compositae) em eqüinos, Pesq Vet Bras, 15, 19

Döbereiner J, 1976, Intoxicação experimental por Baccharis coridifolia em coelhos., Pesq Agropec Bras Sér Vet, 11, 27

10.1039/p19850001553

GroveJF(1993):Macrocyclic trichothecenes. Nat Prod Rep:429–448.

10.1351/pac198961030377

10.1016/0041-0101(85)90003-0

10.1007/BF00336778

10.1111/j.1432-1033.1994.tb19012.x

Jarvis BB, 1991, “Mycotoxins and Phytoalexins in Human and Animal Health.”, 361

10.1002/pca.2800030602

Jarvis BB, 1989, “Trichothecene Mycotoxicosis: Pathophysiologic Effects,”, 73

Jarvis BB, 1989, “The Mystery of Trichothecenes in Higher Plants.” “Mycotoxins and Phycotoxins 1988.”, 197

Jarvis BB, 1988, Phytotoxicity of macrocyclic trichothecenes toward Baccharis cell lines, 199

10.1016/0031-9422(91)85253-V

10.1007/BF00982109

Price P, 1990, Use of tetrazolium assay in measuring the response of human tumor cells to ionizing radiation., Cancer Res, 50, 1392

10.1094/MPMI-8-0593

10.1021/ja00297a055

10.1016/S0957-4166(00)82193-X

Sharma RP, 1991, “Mycotoxins and Phytoalexins in Human and Animal Health.”, 339

Swanson SP, 1989, “Trichothecene Mycotoxicosis: Pathophysiologic Effects,”, 37

Tokarnia CH, 1975, Intoxicação experimental em bovinos por “mio‐mio,” Baccharis coridifolia., Pesq Agropec Bras Sér Vet, 10, 79

Tokarnia CH, 1976, Intoxicação experimental em ovinos por “mio‐mio,” Baccharis coridifolia., Pesq Agropec Bras Sér Vet, 11, 19

Tokarnia CH, 1992, Intoxicação experimental por Baccharis megapotamica var. megapotamica e var. weirii (Compositae) em bovinos, Pesq Vet Bras, 12, 19

10.1016/0272-0590(84)90091-5

10.3109/03602539308993978

Thông tin
Thông tin xuất bản

Wiley

Tập 4 Số 2

58-71

Thông tin tác giả