Bone maintenance and remodeling: A control system based on fatigue damage

Journal of Orthopaedic Research - Tập 15 Số 4 - Trang 601-606 - 1997
David Taylor1
1Bioengineering Research Group, Mechanical Engineering Department, Trinity College, Dublin, Ireland

Tóm tắt

AbstractThis paper explores the relationship between damage, repair, and remodeling in compact bone. A model of microcrack growth is developed that takes account of recent findings on the behaviour of small fatigue cracks in other materials. This is combined with a simple model of a repair process, envisaged as a constant rate of decrease in crack length. The system that results is capable of achieving a stable and precise control of crack length without the need to measure it. This is very useful because it implies that bone does not require the complexities of crack‐measuring, transducers or active decision‐making processes. A simple explanation is suggested for the presence of a “lazy zone” of remodeling equilibrium strains, and the limits of this zone are quantified. The model is developed through a necessarily simplified geometry and loading scheme but can be extended to provide a general solution applicable to in vivo conditions.

Từ khóa


Tài liệu tham khảo

10.1210/edrv-10-1-45

10.1016/0021-9290(85)90204-0

10.1097/00003086-199011000-00047

10.1016/0021-9290(93)90023-8

10.1016/0021-9290(89)90013-4

10.1016/0021-9290(81)90096-8

10.1016/0021-9290(92)90051-2

10.1007/BF02406141

Eriksen EF, 1995, Bone Structure and Remodelling, 25

Frost HM, 1960, Presence of microscopic cracks in vivo in bone, H Ford Hosp Med Bull, 8, 25

Frost HM, 1963, Bone Remodelling Dynamics

Frost HM, 1964, The Laws of Bone Structure

Frost HM, 1983, A determinant of bone architecture: the minimum effective strain, Clin Orthop, 175, 286, 10.1097/00003086-198305000-00047

Goto M, 1992, Short Fatigue Cracks, 485

Huiskes R, 1985, A standardised FE model for routine comparative evaluations of femoral hip prostheses, Trans Orthop Res Soc, 9, 254

HuiskesR WeinansH VenneR ShooffTJ:Effects of interface bonding on stress shielding in cementless THA. Presented at the Nordic Orthopaedic Federation Conference. Aarhus Denmark June 8–11 1998

LeeTC:Functional adaptation in compact bone[Ph.D. thesis] Dublin University of Dublin 1995

10.1002/jor.1100130303

Martin RB, 1989, The Structure, Function and Adaptation of Cortical Bone

Miller KJ, 1986, Short Fatigue Cracks, 491

10.1002/ar.1092420203

Mullender MG, 1995, Bone Structure and Remodeling, 181

Oh I, 1977, Effect of total hip replacement on the distribution of stress in the proximal femur, The Hip, 23, 98

10.1016/0021-9290(94)90223-2

10.2106/00004623-198466030-00012

10.1016/8756-3282(95)00370-3

Taylor D, 1995, Damage accumulation in compact bone: a fracture mechanics approach to estimate damage and repair rates, Adv Bioeng, 13, 337

10.1007/BF00351420

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Thông tin xuất bản

Journal of Orthopaedic Research

Tập 15 Số 4

601-606

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