Body water metabolism in high altitude natives during and after a stay at sea level
Tóm tắt
Body fluid compartments were studied in a group of high altitude natives after a stay of two months at sea level and during 12 days at an altitude of 3,500 m. Measurements of total body water and extracellular water were made on day 3 and 12 of reinduction to altitude, while plasma volume was measured on day 12 only. The intracellular water, blood volume and red cell mass were computed from the above parameters. Total body water and intracellular water decreased by 3.3% (P<0.001) and 5.0% (P<0.001) respectively by the 3rd day at altitude and did not change thereafter. Extracellular water increased progressively at altitude, but the increase was not significant. Blood volume and red cell mass increased significantly while plasma volume decreased at altitude. These data were compared with that of low landers. This study suggested body hypohydration on high altitude induction in low landers as well as in high altitude natives on reinduction.
Tài liệu tham khảo
ANTHONY, A. and KREIDER, J. (1961): Blood volume changes in rodents to high altitude. Amer. J. Physiol., 200: 523–526.
BAUER, F. K. (1971): Radioisotope dilution methods: Measurement of body composition. In: Nuclear Medicine. W. H. Blahd (ed.), McGraw-Hill, New York, 574–592.
CHINN, K. S. K. and HANNON, J. P. (1970): Effects of diet and altitude on the body composition of rats. J. Nutr., 100: 732–738.
CONSOLAZIO, C. F., JOHNSON, H. L. and KRZYWICKI, H. J. (1972): Body fluid, body composition and metabolic aspects of high altitude adaptation. In: Physiological Adaptations — Desert and Mountain. H. K. Yousef, S. M. Horvath and R. W. Bullard (ed.), Academic Press, New York, 227–241.
CONSOLAZIO, C. F., MATOUSH, L. O., JOHNSON, H. L. and DAWS, T. A. (1968): Protein and water balances of young adults during prolonged exposure to high altitude (4300 m). Amer. J. clin. Nutr., 21: 154–161.
FRAYSER, R., RENINE, D. I., GRAY, G. W. and HOUSTON, C. S. (1975): Hormonal and electrolyte response to exposure to 17,500 ft. J. appl. Physiol. 38: 636–642.
HANNON, J. P., CHINN, K. S. K. and SHIELDS, J. L. (1969): Effects of acute altitude exposure on body fluids. Fed. Proc., 28: 1178–1184.
HOBBS, J. H. (1968): Total blood volume: its measurement and significance. Med. Monograph No. 3. The Radiochemical Centre, Amersham.
JAIN, S. C., BARDHAN, J., SWAMY, Y. V., BALKRISHNA, and NAYAR, H. S. (1980): Body fluid compartments in humans during acute high altitude exposure. Aviat. Space environ. Med. 51: 234–236.
JAIN, S. C., GROVER, A., BARDHAN, J., BALKRISHNA, and MALHOTRA, M. S. (1978): Body fluid compartments in rabbits on exposure to acute hypobaric hypoxia. Aviat. Space environ. Med. 49: 895–897.
KRZYWICKI, H. J., CONSOLAZIO, C. F., JOHNSON, H. L. and BARNHART, R. A. (1969): Body composition changes during exposure to altitude. Fed. Proc., 28: 1190–1194.
KRZYWICKI, H. J., CONSOLAZIO, C. F., JOHNSON, H. L., NIELSEN, W. C. and BARNHART, R. A. (1971): Water metabolism in humans during acute altitude exposure (4,300 m). J. appl. Physiol., 30: 806–809.
LESSOR, G. T. and MARKOFSKY, J. (1979): Body water compartments with human aging using fat free mass as the reference standard. Amer. J. Physiol. 236: R215-R220.
MALPARTIDA, M., MONOCLOA, F. (1967): Radiosulphate space in humans at high altitude, Proc. Soc. exp. Biol. Med., 125: 1328–1330.
PICON-REATEGUI, E. (1961): Basal metabolic rate and body composition at high altitude: J. appl. Physiol., 16: 431–434.
PICON-REATEGUI, E., LAZANO, R. and VADIVIESO, J. (1961): Body composition at sea level and high altitude. J. appl. Physiol. 16: 589–592.
PUGH, L. G. C. E. (1962): Physiological and medical aspects of the Himalayan Scientific and Mountaineering Expedition 1960–61. Brit. Med. J. 2: 621–637.
SURKS, M. I., CHINN, K. S. K., MATOUSH, L. O. (1966): Alterations in body composition in man after acute exposure to altitude. J. appl. Physiol. 21: 1741–1746.
WALSER, M., SELDIN, D. V. and GROLLMAN, A. (1953): An evaluation of radiosulphate for the determination of the volume of extracellular fluid in man and dogs. J. clin. Invest., 32: 299–311.
WOLFE, R. B., and HORVATH, S. M. (1976): Haemodynamic responses to acute haematocrit and blood volume alterations in rats. Europ. J. appl. Physiol., 35: 159–166.