Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption
Tóm tắt
Từ khóa
Tài liệu tham khảo
Carson, 1987
Colborn, 1995
Bern, 1992, 9
Kavlock, 1996, Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop., Environ Health Perspect, 104, 715
Vandenberg, 2007, Human exposure to bisphenol A (BPA)., Reprod Toxicol, 24, 139, 10.1016/j.reprotox.2007.07.010
Le, 2008, Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons., Toxicol Lett, 176, 149, 10.1016/j.toxlet.2007.11.001
Morrissey, 1987, The developmental toxicity of bisphenol A in rats and mice., Fundam Appl Toxicol, 8, 571, 10.1016/0272-0590(87)90142-4
Welshons, 2003, Large effects from small exposures: I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity., Environ Health Perspect, 111, 994, 10.1289/ehp.5494
Dodds, 1936, Synthetic estrogenic agents without the phenanthrene nucleus., Nature, 137, 996, 10.1038/137996a0
Gould, 1998, Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol., Mol Cell Endocrinol, 142, 203, 10.1016/S0303-7207(98)00084-7
Kuiper, 1998, Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β., Endocrinology, 139, 4252, 10.1210/endo.139.10.6216
Kitamura, 2005, Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds., Toxicol Sci, 84, 249, 10.1093/toxsci/kfi074
Routledge, 2000, Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) α and ER β., J Biol Chem, 275, 35986, 10.1074/jbc.M006777200
Wetherill, 2007, In vitro molecular mechanisms of bisphenol A action., Reprod Toxicol, 24, 178, 10.1016/j.reprotox.2007.05.010
Soto, 2006, Strengths and weaknesses of in vitro assays for estrogenic and androgenic activity., Best Pract Res Clin Endocrinol Metab, 20, 15, 10.1016/j.beem.2005.09.001
Soto, 1992, 295
Andersen, 1999, Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals., Environ Health Perspect, 107, 89, 10.1289/ehp.99107s189
Fang, 2000, Quantitative comparisons of in vitro assays for estrogenic activities., Environ Health Perspect, 108, 723, 10.1289/ehp.00108723
Welshons, 2006, Large effects from small exposures, III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology, 147, S56
Powell, 2001, Identification and characterization of membrane estrogen receptor from MCF7 estrogen-target cells., J Steroid Biochem Mol Biol, 77, 97, 10.1016/S0960-0760(01)00040-1
Watson, 2007, Xenoestrogens are potent activators of nongenomic estrogenic responses., Steroids, 72, 124, 10.1016/j.steroids.2006.11.002
Thomas, 2006, Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption., J Steroid Biochem Mol Biol, 102, 175, 10.1016/j.jsbmb.2006.09.017
Watson, 2005, Signaling from the membrane via membrane estrogen receptor-α: estrogens, xenoestrogens, and phytoestrogens., Steroids, 70, 364, 10.1016/j.steroids.2005.03.002
Alonso-Magdalena, 2005, Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic α-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans., Environ Health Perspect, 113, 969, 10.1289/ehp.8002
Alonso-Magdalena, 2008, Pancreatic insulin content regulation by the estrogen receptor ER α, PLoS ONE, 3, e2069, 10.1371/journal.pone.0002069
Noguchi, 2002, Bisphenol A stimulates NO synthesis through a non-genomic estrogen receptor-mediated mechanism in mouse endothelial cells., Toxicol Lett, 135, 95, 10.1016/S0378-4274(02)00252-7
Nadal, 2005, Disentangling the molecular mechanisms of action of endogenous and environmental estrogens., Pflugers Arch, 449, 335, 10.1007/s00424-004-1343-9
Markey, 2001, The mouse uterotrophic assay: a re-evaluation of its validity in assessing the estrogenicity of bisphenol A., Environ Health Perspect, 109, 55, 10.1289/ehp.0110955
Steinmetz, 1998, The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract., Endocrinology, 139, 2741, 10.1210/endo.139.6.6027
Colerangle, 1997, Profound effects of the weak environmental estrogen-like chemical bisphenol A on the growth of the mammary gland of Noble rats., J Steroid Biochem Mol Biol, 60, 153, 10.1016/S0960-0760(96)00130-6
Moriyama, 2002, Thyroid hormone action is disrupted by bisphenol A as an antagonist., J Clin Endocrinol Metab, 87, 5185, 10.1210/jc.2002-020209
Kitamura, 2002, Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A., Biochem Biophys Res Commun, 293, 554, 10.1016/S0006-291X(02)00262-0
Zoeller, 2005, Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain., Endocrinology, 146, 607, 10.1210/en.2004-1018
Ramakrishnan, 2008, Impact of bisphenol-A on early embryonic development and reproductive maturation., Reprod Toxicol, 25, 177, 10.1016/j.reprotox.2007.11.002
Sohoni, 1998, Several environmental oestrogens are also anti-androgens., J Endocrinol, 158, 327, 10.1677/joe.0.1580327
Lee, 2003, Antiandrogenic effects of bisphenol A and nonphenol on the function of androgen receptor., Toxicol Sci, 75, 40, 10.1093/toxsci/kfg150
Sun, 2006, Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene., Food Chem Toxicol, 44, 1916, 10.1016/j.fct.2006.06.013
Kruger, 2008, Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor., Toxicology, 246, 112, 10.1016/j.tox.2007.12.028
Gaido, 2000, Interaction of methoxychlor and related compounds with estrogen receptor α and β, and androgen receptor: structure-activity studies., Mol Pharmacol, 58, 852, 10.1124/mol.58.4.852
Akingbemi, 2004, Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells., Endocrinology, 145, 592, 10.1210/en.2003-1174
Matsushima, 2007, Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR γ., J Biochem, 142, 517, 10.1093/jb/mvm158
Takayanagi, 2006, Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRγ) with high constitutive activity., Toxicol Lett, 167, 95, 10.1016/j.toxlet.2006.08.012
Pocar, 2005, Molecular interactions of the aryl hydrocarbon receptor and its biological and toxicological relevance for reproduction., Reproduction, 129, 379, 10.1530/rep.1.00294
Sheehan, 1997, Low dose effects of hormones: a challenge for risk assessment., Risk Policy Report, 4, 31
Vandenberg, 2006, The mammary gland response to estradiol: monotonic at the cellular level, non-monotonic at the tissue-level of organization?, J Steroid Biochem Mol Biol, 101, 263, 10.1016/j.jsbmb.2006.06.028
Conolly, 2004, Nonmonotonic dose-response relationships: mechanistic basis, kinetic modeling, and implications for risk assessment., Toxicol Sci, 77, 151, 10.1093/toxsci/kfh007
Calabrese, 2001, The frequency of U-shaped dose responses in the toxicological literature., Toxicol Sci, 62, 330, 10.1093/toxsci/62.2.330
Medlock, 1991, Estradiol down-regulation of the rat uterine estrogen receptor., Proc Soc Exp Biol Med, 196, 292, 10.3181/00379727-196-43191
Tibbetts, 1998, Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus., Biol Reprod, 59, 1143, 10.1095/biolreprod59.5.1143
Soto, 1995, Variants of the human prostate LNCaP cell line as a tool to study discrete components of the androgen-mediated proliferative response., Oncol Res, 7, 545
Sonnenschein, 1989, Negative controls of cell proliferation: human prostate cancer cells and androgens., Cancer Res, 49, 3474
Geck, 2000, Androgen-induced proliferative quiescence in prostate cancer: the role of AS3 as its mediator., Proc Natl Acad Sci USA, 97, 10185, 10.1073/pnas.97.18.10185
Wozniak, 2005, Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-α mediated Ca++ fluxes and prolactin release in GH3/B6 pituitary tumor cells., Environ Health Perspect, 113, 431, 10.1289/ehp.7505
Wetherill, 2002, The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells., Mol Cancer Ther, 1, 515
Hugo, 2008, Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytes., Environ Health Perspect, 116, 1642, 10.1289/ehp.11537
Richter, 2007, In vivo effects of bisphenol A in laboratory rodent studies., Reprod Toxicol, 24, 199, 10.1016/j.reprotox.2007.06.004
Rubin, 2001, Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels., Environ Health Perspect, 109, 675, 10.1289/ehp.01109675
Honma, 2002, Low dose effects of in utero exposure to bisphenol A and diethylstilbestrol on female mouse reproduction., Reprod Toxicol, 16, 117, 10.1016/S0890-6238(02)00006-0
Gandelman, 1977, Contiguity to male foetuses affects morphology and behaviour of female mice., Nature, 266, 722, 10.1038/266722a0
Vandenbergh, 2004, Animal models and studies of in utero endocrine disruptor effects., ILAR Journal, 45, 438, 10.1093/ilar.45.4.438
Ryan, 2002, Intrauterine position effects., Neurosci Biobehav Rev, 26, 665, 10.1016/S0149-7634(02)00038-6
Saal, 1980, Sexual characteristics of adult female mice are correlated with their blood testosterone levels during prenatal development., Science, 208, 597, 10.1126/science.7367881
Saal, 1978, In utero proximity of female mouse fetuses to males: effect on reproductive performance during later life., Biol Reprod, 19, 842, 10.1095/biolreprod19.4.842
Saal, 1980, Variation in length of estrous cycles in mice due to former intrauterine proximity to male fetuses., Biol Reprod, 22, 777, 10.1095/biolreprod22.4.777
Saal, 1981, Effects of prior intrauterine position and housing on oestrous cycle length in adolescent mice., J Reprod Fertil, 62, 33, 10.1530/jrf.0.0620033
Saal, 2005, The importance of appropriate controls, animal feed, and animal models in interpreting results from low-dose studies of bisphenol A., Birth Defects Res (Part A), 73, 140, 10.1002/bdra.20120
Saal, 1989, Sexual differentiation in litter-bearing mammals: influence of sex of adjacent fetuses in utero., J Anim Sci, 67, 1824, 10.2527/jas1989.6771824x
Timms, 2005, Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra., Proc Natl Acad Sci USA, 102, 7014, 10.1073/pnas.0502544102
Vandenberg, 2007, Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland., Endocrinology, 148, 116, 10.1210/en.2006-0561
Padula, 2005, The freemartin syndrome: an update., Anim Reprod Sci, 87, 93, 10.1016/j.anireprosci.2004.09.008
Satoh, 1997, The possibility of early estimation for fertility in bovine heterosexual twin females., J Vet Med Sci, 59, 221, 10.1292/jvms.59.221
Reiling, 1995, Effect of prenatal androgenization on performance, lactation, carcass, and sensory traits of heifers in a single-calf heifer system., J Anim Sci, 73, 986, 10.2527/1995.734986x
Beek, 2004, Relationships between sex hormones assessed in amniotic fluid, and maternal and umbilical cord serum: what is the best source of information to investigate the effects of fetal hormone exposure?, Horm Behav, 46, 663, 10.1016/j.yhbeh.2004.06.010
Lummaa, 2007, Male twins reduce fitness of female co-twins in humans., Proc Natl Acad Sci USA, 104, 10915, 10.1073/pnas.0605875104
Trichopoulos, 1990, Is breast cancer initiated in utero?, Epidemiology, 1, 95, 10.1097/00001648-199003000-00001
Herbst, 1971, Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women., N Engl J Med, 284, 878, 10.1056/NEJM197104222841604
Palmer, 2006, Prenatal diethylstilbestrol exposure and risk of breast cancer., Cancer Epidemiol Biomarkers Prev, 15, 1509, 10.1158/1055-9965.EPI-06-0109
Markey, 2005, Long-term effects of fetal exposure to low doses of the xenoestrogen bisphenol-A in the female mouse genital tract., Biol Reprod, 72, 1344, 10.1095/biolreprod.104.036301
Saal, 1985, Prenatal effects on reproductive capacity during aging in female mice., Biol Reprod, 32, 1116, 10.1095/biolreprod32.5.1116
Gilbert, 2006
Hermanson, 2002, Nuclear receptor coregulators: multiple modes of modification., Trends Endocrinol Metab, 13, 55, 10.1016/S1043-2760(01)00527-6
Mittendorf, 1995, Teratogen update: carcinogenesis and teratogenesis associated with exposure to diethylstilbestrol (DES) in utero., Teratology, 51, 435, 10.1002/tera.1420510609
Hatch, 2001, Incidence of squamous neoplasia of the cervix and vagina in women exposed prenatally to diethylstilbestrol (United States)., Cancer Causes Control, 12, 837, 10.1023/A:1012229112696
Richert, 2000, An atlas of mouse mammary gland development., J Mammary Gland Biol Neoplasia, 5, 227, 10.1023/A:1026499523505
Rayner, 2005, Adverse effects of prenatal exposure to atrazine during a critical period of mammary gland growth., Toxicol Sci, 87, 255, 10.1093/toxsci/kfi213
Rayner, 2004, Exposure parameters necessary for delayed puberty and mammary gland development in Long-Evans rats exposed in utero to atrazine., Toxicol Appl Pharmacol, 195, 23, 10.1016/j.taap.2003.11.005
Bern, 1983, Critical period of neonatal estrogen exposure in occurrence of mammary gland abnormalities in adult mice., Proc Soc Exp Biol Med, 172, 239, 10.3181/00379727-172-41552
Warner, 2002, Serum dioxin concentrations and breast cancer risk in the Seveso Women’s Health Study., Environ Health Perspect, 110, 625, 10.1289/ehp.02110625
Eskenazi, 2007, Serum dioxin concentrations and endometriosis: a cohort study in Seveso, Italy., Environ Health Perspect, 110, 629, 10.1289/ehp.02110629
Robinson, 1999, Regulation of mammary gland development by tissue interaction., J Mammary Gland Biol Neoplasia, 4, 9, 10.1023/A:1018748418447
Medina, 2001, Mechanisms of hormonal prevention of breast cancer., Ann NY Acad Sci, 952, 23, 10.1111/j.1749-6632.2001.tb02725.x
Saal, 2007, Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure., Reprod Toxicol, 24, 131, 10.1016/j.reprotox.2007.07.005
Tyl, 2008, Two-generation reproductive toxicity study of dietary bisphenol A in CD-1 (Swiss) mice., Toxicol Sci, 104, 362, 10.1093/toxsci/kfn084
Willhite, 2008, Derivation of a Bisphenol A organ reference dose (RfD) and drinking-water equivalent concentration., J Toxicol Environ Health B Crit Rev, 11, 69, 10.1080/10937400701724303
Soto, 2001, The two faces of Janus: sex steroids as mediators of both cell proliferation and cell death., J Natl Cancer Inst, 93, 1673, 10.1093/jnci/93.22.1673
Powell, 2003, Plasma membrane-resident albumin binding protein associated with the proliferation of MCF7 serum-sensitive cells., Steroids, 68, 487, 10.1016/S0039-128X(03)00047-3
Sonnenschein, 1999
Mannan, 1992, Steroidogenesis during postnatal development in the mouse ovary., J Endocrinol, 130, 101, 10.1677/joe.0.1300101
Greco, 1994, Ontogeny of expression of the genes for steroidogenic enzymes P450 side-chain cleavage, 3-β-hydroxysteroid-dehydrogenase, P450 17 α-hydroxylase/C17-20 lyase, and P450 aromatase in fetal mouse gonads., Endocrinology, 135, 262, 10.1210/endo.135.1.8013361
Nagel, 1999, Developmental effects of estrogenic chemicals are predicted by an in vitro assay incorporating modification of cell uptake by serum., J Steroid Biochem Mol Biol, 69, 343, 10.1016/S0960-0760(99)00078-3
Rajapakse, 2002, Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone activity., Environ Health Perspect, 110, 917, 10.1289/ehp.02110917
Ma, 2006, PCBs exert an estrogenic effect through repression of the Wnt7a signaling pathway in the female reproductive tract., Environ Health Perspect, 114, 898, 10.1289/ehp.8748
Ma, 1998, Abdominal B (AbdB) Hoxa genes: regulation in adult uterus by estrogen and progesterone and repression in mullerian duct by the synthetic estrogen diethylstilbestrol (DES)., Dev Biol, 197, 141, 10.1006/dbio.1998.8907
Soto, 2008, Does breast cancer start in the womb?, Basic Clin Pharmacol Toxicol, 102, 125, 10.1111/j.1742-7843.2007.00165.x
Diel, 2000, Ability of xeno- and phytoestrogens to modulate expression of estrogen-sensitive genes in rat uterus: estrogenicity profiles and uterotropic activity., J Steroid Biochem Mol Biol, 73, 1, 10.1016/S0960-0760(00)00051-0
Naciff, 2002, Gene expression profile induced by 17α-ethynyl estradiol, bisphenol A, and genistein in the developing female reproductive system of the rat., Toxicol Sci, 68, 184, 10.1093/toxsci/68.1.184
Barker, 2003, The developmental origins of adult disease., Eur J Endocrinol, 18, 733
Barker, 2004, Altered regional blood flow in the fetus: the origins of cardiovascular disease?, Acta Paediatricia, 93, 1559, 10.1111/j.1651-2227.2004.tb00842.x
Soto, 2008, Neoplasia as development gone awry: the role of endocrine disruptors., Int J Androl, 31, 288, 10.1111/j.1365-2605.2007.00834.x
Calafat, 2005, Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population., Environ Health Perspect, 113, 391, 10.1289/ehp.7534
Calafat, 2008, Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003–2004., Environ Health Perspect, 116, 39, 10.1289/ehp.10753
Dekant, 2008, Human exposure to bisphenol A by biomonitoring: methods: results and assessment of environmental exposures., Toxicol Appl Pharmacol, 228, 114, 10.1016/j.taap.2007.12.008
Fukata, 2006, Comparison of ELISA- and LC-MS-based methodologies for the exposure assessment of bisphenol A., Toxicol Mech Methods, 16, 427, 10.1080/15376520600697404
Atkinson, 2002, Stability of bisphenol A, triethylene glycol dimethylacrylate, and bisphenol A dimethylacrylate in whole saliva., Dent Mater, 18, 128, 10.1016/S0109-5641(01)00031-8
Lang, 2008, Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults., JAMA, 300, 1303, 10.1001/jama.300.11.1303
Yamada, 2002, Maternal serum and amniotic fluid bisphenol A concentrations in the early second trimester., Reprod Toxicol, 16, 735, 10.1016/S0890-6238(02)00051-5
Yang, 2006, Urinary concentrations of bisphenol A in relation to biomarkers of sensitivity and effect and endocrine-related health effects., Environ Mol Mutagen, 47, 571, 10.1002/em.20230
Wilson, 2003, Aggregate exposures of nine preschool children to persistent organic pollutants at day care and at home., J Expo Anal Environ Epidemiol, 13, 187, 10.1038/sj.jea.7500270
Wilson, 2007, An observational study of the potential exposures of preschool children to pentachlorophenol, bisphenol-A, and nonylphenol at home and daycare., Environ Res, 103, 9, 10.1016/j.envres.2006.04.006
Yokota, 1999, Glucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liver., Biochem J, 340, 405, 10.1042/bj3400405
Ye, 2005, Quantification of urinary conjugates of bisphenol A, 2,5-dichlorophenol, and 2- hydroxy-4-methoxybenzophenone in humans by online solid phase extraction-high performance liquid chromatography-tandem mass spectrometry., Anal Bioanal Chem, 383, 638, 10.1007/s00216-005-0019-4
Suiko, 2000, Sulfation of environment estrogen-like chemicals by cytosolic sulfotransferases., Biochem Biophys Res Commun, 267, 80, 10.1006/bbrc.1999.1935
Shimizu, 2002, Sulfation of bisphenol A abolished its estrogenicity based on proliferation and gene expression in human breast cancer MCF-7 cells., Toxicol in Vitro, 16, 549, 10.1016/S0887-2333(02)00055-3
Kim, 2003, Gender differences in the levels of bisphenol A metabolites in urine., Biochem Biophys Res Commun, 312, 441, 10.1016/j.bbrc.2003.10.135
Zalko, 2003, Biotransformations of bisphenol A in a mammalian model: answers and new questions raised by low-dose metabolic fate studies in pregnant CD1 mice., Environ Health Perspect, 111, 309, 10.1289/ehp.5603
Sakamoto, 2002, Excretion of bisphenol A-glucuronide into the small intestine and deconjugation in the cecum of the rat., Biochemica et Biophysica Acta, 1573, 171, 10.1016/S0304-4165(02)00418-X
Mykkanen, 1997, Fecal bacterial enzyme activities in infants increase with age and adoption of adult-type diet., J Pediatr Gastroenterol Nutr, 25, 312, 10.1097/00005176-199709000-00012
Taylor, 2008, No effect of route of exposure (oral; subcutaneous injection) on plasma bisphenol A throughout 24h after administration in neonatal female mice., Reprod Toxicol, 25, 169, 10.1016/j.reprotox.2008.01.001
Stowell, 2006, A role for sulfation-desulfation in the uptake of bisphenol A into breast tumor cells., Chem Biol, 13, 891, 10.1016/j.chembiol.2006.06.016
Miyakoda, 2000, Comparison of conjugative activity, conversion of bisphenol A to bisphenol A glucuronide, in fetal and mature male rat., J Health Sci, 46, 269, 10.1248/jhs.46.269
Takahashi, 2000, Disposition of orally administered 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in pregnant rats and placental transfer to fetuses., Environ Health Perspect, 108, 931, 10.1289/ehp.00108931
Matsumoto, 2002, Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy., Environ Health Perspect, 110, 193, 10.1289/ehp.02110193
Schonfelder, 2002, Parent bisphenol A accumulation in the human maternal-fetal-placental unit, Environ Health Perspect, 110, A703, 10.1289/ehp.021100703
Kurebayashi, 2003, Disposition of a low dose of 14C-bisphenol A in male rats and its main bilary excretion as BPA glucuronide., Toxicol Sci, 73, 17, 10.1093/toxsci/kfg040
Tominaga, 2006, Toxicokinetics of bisphenol A in rats, monkeys and chimpanzees by the LC-MS/MS method., Toxicology, 226, 208, 10.1016/j.tox.2006.07.004
Uchida, 2002, Bisphenol-A administration during pregnancy results in fetal exposure in mice and monkeys., J Health Sci, 48, 579, 10.1248/jhs.48.579
Volkel, 2002, Metabolism and kinetics of bisphenol A in humans at low doses following oral administration., Chem Res Toxicol, 15, 1281, 10.1021/tx025548t
Volkel, 2005, Quantitation of bisphenol A and bisphenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry., Drug Metab Dispos, 33, 1748, 10.1124/dmd.105.005454
Soto, 1997, Developing a marker of exposure to xenoestrogen mixtures in human serum., Environ Health Perspect, 105, 647
Couse, 1999, Estrogen receptor null mice: what have we learned and where will they lead us?, Endocr Rev, 20, 358, 10.1210/edrv.20.3.0370
Saal, 2005, An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment., Environ Health Perspect, 113, 926, 10.1289/ehp.7713
Rubin, 2006, Evidence of altered brain sexual differentiation in mice exposed perinatally to low, environmentally relevant levels of bisphenol A., Endocrinology, 147, 3681, 10.1210/en.2006-0189
Kawai, 2003, Aggressive behavior and serum testosterone concentration during the maturation process of male mice: the effects of fetal exposure to bisphenol A., Environ Health Perspect, 111, 175, 10.1289/ehp.5440
Farabollini, 2002, Effects of perinatal exposure to bisphenol A on sociosexual behavior of female and male rats., Environ Health Perspect, 110, 409, 10.1289/ehp.02110s3409
Dessi-Fulgheri, 2002
Porrini, 2005, Early exposure to a low dose of bisphenol A affects socio-sexual behavior of juvenile female rats., Brain Res Bull, 65, 261, 10.1016/j.brainresbull.2004.11.014
Palanza, 2002, Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice., Environ Health Perspect, 110, 415, 10.1289/ehp.02110s3415
Laviola, 2005, D-Amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors., Brain Res Bull, 65, 235, 10.1016/j.brainresbull.2004.11.015
Wallen, 2002, 385
Heines, 2002, 425
Kabuto, 2004, Exposure to bisphenol A during embryonic/fetal life and infancy increases oxidative injury and causes underdevelopment of the brain and testis in mice., Life Sci, 74, 2931, 10.1016/j.lfs.2003.07.060
Welshons, 1999, Low-dose bioactivity of xenoestrogens in animals: fetal exposure to low doses of methoxychlor and other xenoestrogens increases adult prostate size in mice., Toxicol Ind Health, 15, 12, 10.1191/074823399678846745
Ramos, 2001, Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate., Biol Reprod, 65, 1271, 10.1095/biolreprod65.4.1271
Markey, 2003, Mammalian development in a changing environment: exposure to endocrine disruptors reveals the developmental plasticity of steroid-hormone target organs., Evol Dev, 5, 67, 10.1046/j.1525-142X.2003.03011.x
Susiarjo, 2007, Bisphenol A exposure in utero disrupts early oogenesis in the mouse, PLoS Genetics, 3, e5, 10.1371/journal.pgen.0030005
Markey, 2001, In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland., Biol Reprod, 65, 1215, 10.1093/biolreprod/65.4.1215
Munoz-de-Toro, 2005, Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice., Endocrinology, 146, 4138, 10.1210/en.2005-0340
Wadia, 2007, Perinatal bisphenol A exposure increases estrogen sensitivity of the mammary gland in diverse mouse strains., Environ Health Perspect, 115, 592, 10.1289/ehp.9640
Vandenberg, 2008, Perinatal exposure to the xenoestrogen bisphenol-A induces mammary intraductal hyperplasias in adult CD-1 mice., Reprod Toxicol, 26, 210, 10.1016/j.reprotox.2008.09.015
Yoshino, 2004, Prenatal exposure to bisphenol A up-regulates immune responses, including T helper 1 and T helper 2 responses, in mice., Immunology, 112, 489, 10.1111/j.1365-2567.2004.01900.x
Saal, 2005, Commercial animal feed: variability in estrogenic activity and effects on body weight in mice., Birth Defects Res (Part A), 73, 474, 10.1002/bdra.20149
Heindel, 2008, Meeting report: batch-to-batch variability in estrogenic activity in commercial animal diets—importance and approaches for laboratory animal research., Environ Health Perspect, 116, 389, 10.1289/ehp.10524
Takai, 2001, Preimplantation exposure to bisphenol A advances postnatal development., Reprod Toxicol, 15, 71, 10.1016/S0890-6238(00)00119-2
Soto, 2007
Clarke, 2000, Introduction and overview: sex steroids in the mammary gland., J Mammary Gland Biol Neoplasia, 5, 245, 10.1023/A:1009527609611
Sakakura, 1976, Mesenchyme-dependent morphogenesis and epithelium-specific cytodifferentiation in mouse mammary gland., Science, 194, 1439, 10.1126/science.827022
Sugiura-Ogaswara, 2005, Exposure to bisphenol A is associated with recurrent miscarriage., Hum Reprod, 20, 2325, 10.1093/humrep/deh888
Huff, 2001, Carcinogenicity of bisphenol-A in Fischer rats and B6C3F1 mice., Odontology, 89, 12, 10.1007/s10266-001-8179-y
Ho, 2006, Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4., Cancer Res, 66, 5624, 10.1158/0008-5472.CAN-06-0516
Russo, 1978, DNA labeling index and structure of the rat mammary gland as determinants of its susceptibility to carcinogenesis., J Natl Cancer Inst, 61, 1451
McCormack, 2006, Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis., Cancer Epidem Biomar, 15, 1159, 10.1158/1055-9965.EPI-06-0034
Nandi, 1995, Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis., Proc Natl Acad Sci USA, 92, 3650, 10.1073/pnas.92.9.3650
Murray, 2007, Induction of mammary gland ductal hyperplasias and carcinomas in situ following fetal bisphenol A exposure., Reprod Toxicol, 23, 383, 10.1016/j.reprotox.2006.10.002
Durando, 2007, Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats., Environ Health Perspect, 115, 80, 10.1289/ehp.9282
LaPensee, 8 2008
Pike, 1993, Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk., Epidemiol Rev, 15, 17, 10.1093/oxfordjournals.epirev.a036102
Ekbom, 1992, Evidence of prenatal influences on breast cancer risk., Lancet, 340, 1015, 10.1016/0140-6736(92)93019-J
Tyl, 2002, Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats., Toxicol Sci, 68, 121, 10.1093/toxsci/68.1.121
Saal, 2006, Large effects from small exposures. II. The importance of positive controls in low-dose research on bisphenol A., Environ Res, 100, 50, 10.1016/j.envres.2005.09.001
Leranth, 2008, Bisphenol A prevents the synaptogenic response to estradiol in hippocampus and prefrontal cortex of ovariectomized nonhuman primates., Proc Natl Acad Sci USA, 105, 14187, 10.1073/pnas.0806139105