Biomarkers for Primary Sjögren’s Syndrome

Greenspan, 1974, The histopathology of Sjogren’s syndrome in labial salivary gland biopsies, Oral Surg Oral Med Oral Pathol, 37, 217, 10.1016/0030-4220(74)90417-4 Fox, 2007, Autoimmune diseases and Sjogren’s syndrome: an autoimmune exocrinopathy, Ann N Y Acad Sci, 1098, 15, 10.1196/annals.1384.003 Mackay, 2007, An important role for B-cell activation factor and B cells in the pathogenesis of Sjogren’s syndrome, Curr Opin Rheumatol, 19, 406, 10.1097/BOR.0b013e328277ef4c Ekstrom Smedby, 2008, Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium, Blood, 111, 4029, 10.1182/blood-2007-10-119974 Vitali, 2002, Classification criteria for Sjogren’s syndrome: a revised version of the European criteria proposed by the American-European Consensus Group, Ann Rheum Dis, 61, 554, 10.1136/ard.61.6.554 Segal, 2009, Primary Sjogren’s Syndrome: health experiences and predictors of health quality among patients in the United States, Health Qual Life Outcomes, 7, 46, 10.1186/1477-7525-7-46 Kavanaugh, 2000, Guidelines for clinical use of the antinuclear antibody test and tests for specific autoantibodies to nuclear antigens, Arch Pathol Lab Med, 124, 71, 10.5858/2000-124-0071-GFCUOT Shiboski, 2012, American College of Rheumatology classification criteria for Sjogren’s syndrome: a data-driven, expert consensus approach in the Sjogren’s International Collaborative Clinical Alliance cohort, Arthritis Care Res (Hoboken), 64, 475, 10.1002/acr.21591 Yoshizawa, 2013, Salivary biomarkers: toward future clinical and diagnostic utilities, Clin Microbiol Rev, 26, 781, 10.1128/CMR.00021-13 Henson, 2010, Collection, storage, and processing of saliva samples for downstream molecular applications, Methods Mol Biol, 666, 21, 10.1007/978-1-60761-820-1_2 Xiao, 2012, Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry, Mol Cell Proteomics, 11, 10.1074/mcp.M111.012112 Hu, 2007, Salivary proteomic and genomic biomarkers for primary Sjogren’s syndrome, Arthritis Rheum, 56, 3588, 10.1002/art.22954 Fleissig, 2009, Different proteomic protein patterns in saliva of Sjogren’s syndrome patients, Oral Dis, 15, 61, 10.1111/j.1601-0825.2008.01465.x Deutsch, 2015, Identification of Sjogren’s syndrome oral fluid biomarker candidates following high-abundance protein depletion, Rheumatology (Oxford), 54, 884, 10.1093/rheumatology/keu405 Rawe, 2006, Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesis, Hum Reprod, 21, 1143, 10.1093/humrep/dei480 Botre, 2003, Effect of anti-carbonic anhydrase antibodies on carbonic anhydrases I and II, Clin Chem, 49, 1221, 10.1373/49.7.1221 Delaleu, 2015, High fidelity between saliva proteomics and the biologic state of salivary glands defines biomarker signatures for primary Sjogren’s syndrome, Arthritis Rheumatol, 67, 1084, 10.1002/art.39015 Nguyen, 2007, IL-4-STAT6 signal transduction-dependent induction of the clinical phase of Sjogren’s syndrome-like disease of the nonobese diabetic mouse, J Immunol, 179, 382, 10.4049/jimmunol.179.1.382 Horikawa, 2006, Interleukin-5 regulates genes involved in B-cell terminal maturation, Immunology, 118, 497 Koltai, 2014, Clusterin: a key player in cancer chemoresistance and its inhibition, Onco Targets Ther, 7, 447, 10.2147/OTT.S58622 Tomosugi, 2005, Diagnostic potential of tear proteomic patterns in Sjogren’s syndrome, J Proteome Res, 4, 820, 10.1021/pr0497576 Hamm-Alvarez, 2014, Tear cathepsin S as a candidate biomarker for Sjogren’s syndrome, Arthritis Rheumatol, 66, 1872, 10.1002/art.38633 Maria, 2014, MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjogren’s syndrome, Ann Rheum Dis, 73, 1052, 10.1136/annrheumdis-2012-202552 Hjelmervik, 2005, Gene expression profiling of minor salivary glands clearly distinguishes primary Sjogren’s syndrome patients from healthy control subjects, Arthritis Rheum, 52, 1534, 10.1002/art.21006 Bave, 2005, Activation of the type I interferon system in primary Sjogren’s syndrome: a possible etiopathogenic mechanism, Arthritis Rheum, 52, 1185, 10.1002/art.20998 Brkic, 2014, Type I IFN signature in primary Sjogren’s syndrome patients, Expert Rev Clin Immunol, 10, 457, 10.1586/1744666X.2014.876364 Brkic, 2013, Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogren’s syndrome and association with disease activity and BAFF gene expression, Ann Rheum Dis, 72, 728, 10.1136/annrheumdis-2012-201381 Emamian, 2009, Peripheral blood gene expression profiling in Sjogren’s syndrome, Genes Immun, 10, 285, 10.1038/gene.2009.20 Quartuccio, 2014, Biomarkers of lymphoma in Sjogren’s syndrome and evaluation of the lymphoma risk in prelymphomatous conditions: results of a multicenter study, J Autoimmun, 51, 75, 10.1016/j.jaut.2013.10.002 Tobon, 2013, Role of Fms-like tyrosine kinase 3 ligand as a potential biologic marker of lymphoma in primary Sjogren’s syndrome, Arthritis Rheum, 65, 3218, 10.1002/art.38129 Kramer, 2013, CXCL13 is elevated in Sjogren’s syndrome in mice and humans and is implicated in disease pathogenesis, J Leukoc Biol, 94, 1079, 10.1189/jlb.0113036 Lee, 2010, Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis, J Rheumatol, 37, 45, 10.3899/jrheum.090450 Chua, 2009, MicroRNAs: biogenesis, function and applications, Curr Opin Mol Ther, 11, 189 Tandon, 2012, Deep sequencing of short RNAs reveals novel microRNAs in minor salivary glands of patients with Sjogren’s syndrome, Oral Dis, 18, 127, 10.1111/j.1601-0825.2011.01849.x Konsta, 2014, The contribution of epigenetics in Sjogren’s Syndrome, Front Genet, 5, 71, 10.3389/fgene.2014.00071 Gallo, 2012, The majority of microRNAs detectable in serum and saliva is concentrated in exosomes, PLoS One, 7, e30679, 10.1371/journal.pone.0030679 Gallo, 2014, Discovery and validation of novel microRNAs in Sjogren’s syndrome salivary glands, Clin Exp Rheumatol, 32, 761 Alevizos, 2011, MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjogren’s syndrome, Arthritis Rheum, 63, 535, 10.1002/art.30131 Pauley, 2011, Altered miR-146a expression in Sjogren’s syndrome and its functional role in innate immunity, Eur J Immunol, 41, 2029, 10.1002/eji.201040757 Ice, 2015, Characterization of a Sjögren’s syndrome-associated long non-coding RNA at 2P25.1, Ann Rheum Dis, 74, 794 Thabet, 2013, Epigenetic dysregulation in salivary glands from patients with primary Sjogren’s syndrome may be ascribed to infiltrating B cells, J Autoimmun, 41, 175, 10.1016/j.jaut.2013.02.002