Genomics, Proteomics & Bioinformatics
SCIE-ISI SCOPUS (2003-2024)
1672-0229
Cơ quản chủ quản: Elsevier , Beijing Genomics Institute
Lĩnh vực:
Computational MathematicsMolecular BiologyMedicine (miscellaneous)GeneticsBiochemistry
Các bài báo tiêu biểu
KaKs_Calculator: Calculating Ka and Ks Through Model Selection and Model Averaging
Tập 4 Số 4 - Trang 259-263 - 2006
Abstract KaKs_Calculator is a software package that calculates nonsynonymous
(Ka) and synonymous (Ks) substitution rates through model selection and model
averaging. Since existing methods for this estimation adopt their specific
mutation (substitution) models that consider different evolutionary features,
leading to diverse estimates, KaKs_Calculator implements a set of candidate
models in a maxi...
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)
Tập 16 Số 3 - Trang 172-186 - 2018
Abstract As a dioxygenase, Ten-Eleven Translocation 2 (TET2) catalyzes
subsequent steps of 5-methylcytosine (5mC) oxidation. TET2 plays a critical role
in the self-renewal, proliferation, and differentiation of hematopoietic stem
cells, but its impact on mature hematopoietic cells is not well-characterized.
Here we show that Tet2 plays an essential role in osteoclastogenesis. Deletion
of Tet2 impa...
A Stack-Based Ensemble Framework for Detecting Cancer MicroRNA Biomarkers
Tập 15 Số 6 - Trang 381-388 - 2017
Abstract MicroRNA (miRNA) plays vital roles in biological processes like RNA
splicing and regulation of gene expression. Studies have revealed that there
might be possible links between oncogenesis and expression profiles of some
miRNAs, due to their differential expression between normal and tumor tissues.
However, the automatic classification of miRNAs into different categories by
considering th...
GranatumX: A Community-engaging, Modularized, and Flexible Webtool for Single-cell Data Analysis
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The Most Redundant Sequences in Human CpG Island Library Are Derived from Mitochondrial Genome
Tập 8 - Trang 81-91 - 2010
Identification of Age-associated Proteins and Functional Alterations in Human Retinal Pigment Epithelium
Tập 20 - Trang 633-647 - 2022
Normalization Using Weighted Negative Second Order Exponential Error Functions (NeONORM) Provides Robustness Against Asymmetries in Comparative Transcriptome Profiles and Avoids False Calls
Tập 4 - Trang 90-109 - 2006
Systematic exploration of optimized base editing gRNA design and pleiotropic effects with BExplorer
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