Genomics, Proteomics & Bioinformatics
SCIE-ISI SCOPUS (2003-2023)
1672-0229
Cơ quản chủ quản: Elsevier , Beijing Genomics Institute
Lĩnh vực:
Computational MathematicsMolecular BiologyMedicine (miscellaneous)GeneticsBiochemistry
Các bài báo tiêu biểu
KaKs_Calculator: Calculating Ka and Ks Through Model Selection and Model AveragingAbstract
KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their specific mutation (substitution) models that consider different evolutionary features, leading to diverse estimates, KaKs_Calculato... ...
Tập 4 Số 4 - Trang 259-263 - 2006
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)Abstract
As a dioxygenase, Ten-Eleven Translocation 2 (TET2) catalyzes subsequent steps of 5-methylcytosine (5mC) oxidation. TET2 plays a critical role in the self-renewal, proliferation, and differentiation of hematopoietic stem cells, but its impact on mature hematopoietic cells is not well-characterized. Here we show that Tet2 plays an essential r... ...
Tập 16 Số 3 - Trang 172-186 - 2018
A Stack-Based Ensemble Framework for Detecting Cancer MicroRNA BiomarkersAbstract
MicroRNA (miRNA) plays vital roles in biological processes like RNA splicing and regulation of gene expression. Studies have revealed that there might be possible links between oncogenesis and expression profiles of some miRNAs, due to their differential expression between normal and tumor tissues. However, the automatic classification of mi... ...
Tập 15 Số 6 - Trang 381-388 - 2017
GranatumX: A Community-engaging, Modularized, and Flexible Webtool for Single-cell Data Analysis
Tập 19 - Trang 452-460 - 2021
Identification of Age-associated Proteins and Functional Alterations in Human Retinal Pigment Epithelium
Tập 20 - Trang 633-647 - 2022
Normalization Using Weighted Negative Second Order Exponential Error Functions (NeONORM) Provides Robustness Against Asymmetries in Comparative Transcriptome Profiles and Avoids False Calls
Tập 4 - Trang 90-109 - 2006
The Most Redundant Sequences in Human CpG Island Library Are Derived from Mitochondrial Genome
Tập 8 - Trang 81-91 - 2010