Better prognostic accuracy in younger mild cognitive impairment patients with more years of education

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - Tập 10 - Trang 402-412 - 2018
Mattias Göthlin1, Marie Eckerström1, Sindre Rolstad1, Petronella Kettunen1, Anders Wallin1
1Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden

Tóm tắt

AbstractIntroductionAge and years of education influence the risk of dementia and may impact the prognostic accuracy of mild cognitive impairment subtypes.MethodsMemory clinic patients without dementia (N = 358, age 64.0 ± 7.9) were stratified into four groups based on years of age (≤64 and ≥65) and education (≤12 and ≥13), examined with a neuropsychological test battery at baseline and followed up after 2 years.ResultsThe prognostic accuracy of amnestic multi‐domain mild cognitive impairment for dementia was highest in younger patients with more years of education and lowest in older patients with fewer years of education. Conversely, conversion rates to dementia were lowest in younger patients with more years of education and highest in older patients with fewer years of education.DiscussionMild cognitive impairment subtypes and demographic information should be combined to increase the accuracy of prognoses for dementia.

Tài liệu tham khảo

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Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

Tập 10

402-412

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