Basal metabolic rate studies in humans: measurement and development of new equations

Public Health Nutrition - Tập 8 Số 7a - Trang 1133-1152 - 2005
Christiani Jeyakumar Henry1
1School of Biological and Molecular Sciences, Oxford Brookes University, Gipsy Lane Campus, Oxford OX3 0BP, UK

Tóm tắt

AbstractObjective

To facilitate the Food and Agriculture Organization/World Health Organization/United Nations University Joint (FAO/WHO/UNU) Expert Consultation on Energy and Protein Requirements which met in Rome in 1981, Schofieldet al.reviewed the literature and produced predictive equations for both sexes for the following ages: 0–3, 3–10, 10–18, 18–30, 30–60 and >60 years. These formed the basis for the equations used in 1985 FAO/WHO/UNU document,Energy and Protein Requirements.

While Schofield's analysis has served a significant role in re-establishing the importance of using basal metabolic rate (BMR) to predict human energy requirements, recent workers have subsequently queried the universal validity and application of these equations. A survey of the most recent studies (1980–2000) in BMR suggests that in most cases the current FAO/WHO/UNU predictive equations overestimate BMR in many communities. The FAO/WHO/UNU equations to predict BMR were developed using a database that contained a disproportionate number – 3388 out of 7173 (47%) – of Italian subjects. The Schofield database contained relatively few subjects from the tropical region.

The objective here is to review the historical development in the measurement and application of BMR and to critically review the Schofieldet al.BMR database presenting a series of new equations to predict BMR.

Design

This division, while arbitrary, will enable readers who wish to omit the historical review of BMR to concentrate on the evolution of the new BMR equations.

Setting

BMR data collected from published and measured values.

Subjects

A series of new equations (Oxford equations) have been developed using a data set of 10 552 BMR values that (1) excluded all the Italian subjects and (2) included a much larger number (4018) of people from the tropics.

Results

In general, the Oxford equations tend to produce lower BMR values than the current FAO/WHO/UNU equations in 18–30 and 30–60 year old males and in all females over 18 years of age.

Conclusions

This is an opportune moment to re-examine the role and place of BMR measurements in estimating total energy requirements today. The Oxford equations' future use and application will surely depend on their ability to predict more accurately the BMR in contemporary populations.

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