Asymmetric HIV-1 co-receptor use and replication in CD4+ T lymphocytes
Tóm tắt
Từ khóa
Tài liệu tham khảo
Klatzmann D, Champagne E, Chamaret S, Gruest J, Guetard D, Hercend T: T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature. 1984, 312: 767-768. 10.1038/312767a0.
Dalgleish AG, Beverley PC, Clapham PR, Crawford DH, Greaves MF, Weiss RA: The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature. 1984, 312: 763-767. 10.1038/312763a0.
McDougal JS, Maddon PJ, Dalgleish AG, Clapham PR, Littman DR, Godfrey M: The T4 glycoprotein is a cell-surface receptor for the AIDS virus. Cold Spring Harb Symp Quant Biol. 1986, 51 (Pt 2): 703-711.
Harouse JM, Kunsch C, Hartle HT, Laughlin MA, Hoxie JA, Wigdahl B, Gonzalez-Scarano F: CD4-independent infection of human neural cells by human immunodeficiency virus type 1. J Virol. 1989, 63: 2527-2533.
Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA: CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science. 1996, 272: 1955-1958. 10.1126/science.272.5270.1955.
Clapham PR, Blanc D, Weiss RA: Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by Simian immunodeficiency virus. Virology. 1991, 181: 703-715. 10.1016/0042-6822(91)90904-P.
Harrington RD, Geballe AP: Cofactor requirement for human immunodeficiency virus type 1 entry into a CD4-expressing human cell line. J Virol. 1993, 67: 5939-5947.
Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD: The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 1996, 85: 1135-1148. 10.1016/S0092-8674(00)81313-6.
Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M: Identification of a major co-receptor for primary isolates of HIV-1. Nature. 1996, 381: 661-666. 10.1038/381661a0.
Feng Y, Broder CC, Kennedy PE, Berger EA: HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 1996, 272: 872-877. 10.1126/science.272.5263.872.
Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature. 1996, 382: 833-835. 10.1038/382833a0.
Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC: A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell. 1996, 85: 1149-1158. 10.1016/S0092-8674(00)81314-8.
Tersmette M, Gruters RA, de Wolf F, de Goede RE, Lange JM, Schellekens PT: Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates. J Virol. 1989, 63: 2118-2125.
Schuitemaker H, Koot M, Kootstra NA, Dercksen MW, de Goede RE, van Steenwijk RP: Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J Virol. 1992, 66: 1354-1360.
Cocchi F, DeVico AL, Garzino-Demo A, Cara A, Gallo RC, Lusso P: The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection. Nat Med. 1996, 2: 1244-1247. 10.1038/nm1196-1244.
Farzan M, Choe H, Martin KA, Sun Y, Sidelko M, Mackay CR: HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5. J Biol Chem. 1997, 272: 6854-6857. 10.1074/jbc.272.11.6854.
Sprent J: The thymus and T-cell tolerance. Ann N Y Acad Sci. 1993, 681: 5-15. 10.1111/j.1749-6632.1993.tb22863.x.
Ho Tsong Fang R, Colantonio AD, Uittenbogaart CH: The role of the thymus in HIV infection: a 10 year perspective. AIDS. 2008, 22: 171-184. 10.1097/QAD.0b013e3282f2589b.
Campbell JJ, Bowman EP, Murphy K, Youngman KR, Siani MA, Thompson DA: 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7. J Cell Biol. 1998, 141: 1053-1059. 10.1083/jcb.141.4.1053.
Forster R, Schubel A, Breitfeld D, Kremmer E, Renner-Muller I, Wolf E, Lipp M: CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell. 1999, 99: 23-33. 10.1016/S0092-8674(00)80059-8.
Sallusto F, Geginat J, Lanzavecchia A: Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol. 2004, 22: 745-763. 10.1146/annurev.immunol.22.012703.104702.
Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D: Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J Virol. 1998, 72: 2855-2864.
Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW: Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A. 1999, 96: 5215-5220. 10.1073/pnas.96.9.5215.
Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y: HIV preferentially infects HIV-specific CD4+ T cells. Nature. 2002, 417: 95-98. 10.1038/417095a.
Bleul CC, Wu L, Hoxie JA, Springer TA, Mackay CR: The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A. 1997, 94: 1925-1930. 10.1073/pnas.94.5.1925.
Granelli-Piperno A, Delgado E, Finkel V, Paxton W, Steinman RM: Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells. J Virol. 1998, 72: 2733-2737.
Unutmaz D, Littman DR: Expression pattern of HIV-1 coreceptors on T cells, implications for viral transmission and lymphocyte homing. Proc Natl Acad Sci U S A. 1997, 94: 1615-1618. 10.1073/pnas.94.5.1615.
Riley JL, Levine BL, Craighead N, Francomano T, Kim D, Carroll RG, June CH: Naive and memory CD4 T cells differ in their susceptibilities to human immunodeficiency virus type 1 infection following CD28 costimulation: implicatip6s for transmission and pathogenesis. J Virol. 1998, 72: 8273-8280.
Riley JL, Carroll RG, Levine BL, Bernstein W, St Louis DC, Weislow OS, June CH: Intrinsic resistance to T cell infection with HIV type 1 induced by CD28 costimulation. J Immunol. 1997, 158: 5545-5553.
Levine BL, Mosca JD, Riley JL, Carroll RG, Vahey MT, Jagodzinski LL: Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation. Science. 1996, 272: 1939-1943. 10.1126/science.272.5270.1939.
Loetscher P, Seitz M, Baggiolini M, Moser B: Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med. 1996, 184: 569-577. 10.1084/jem.184.2.569.
Jourdan P, Abbal C, Noraz N, Hori T, Uchiyama T, Vendrell JP: IL-4 induces functional cell-surface expression of CXCR4 on human T cells. J Immunol. 1998, 160: 4153-4157.
Galli G, Annunziato F, Mavilia C, Romagnani P, Cosmi L, Manetti R: Enhanced HIV expression during Th2-oriented responses explained by the opposite regulatory effect of IL-4 and IFN-gamma of fusin/CXCR4. Eur J Immunol. 1998, 28: 3280-3290. 10.1002/(SICI)1521-4141(199810)28:10<3280::AID-IMMU3280>3.0.CO;2-M.
Carroll RG, Riley JL, Levine BL, Feng Y, Kaushal S, Ritchey DW: Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells. Science. 1997, 276: 273-276. 10.1126/science.276.5310.273.
Kornbluth RS, Kee K, Richman DD: CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive beta-chemokines. Proc Natl Acad Sci U S A. 1998, 95: 5205-5210. 10.1073/pnas.95.9.5205.
Eckstein DA, Penn ML, Korin YD, Scripture-Adams DD, Zack JA, Kreisberg JF: HIV-1 actively replicates in naive CD4(+) T cells residing within human lymphoid tissues. Immunity. 2001, 15: 671-682. 10.1016/S1074-7613(01)00217-5.
Grivel JC, Margolis LB: CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue. Nat Med. 1999, 5: 344-346. 10.1038/6565.
Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ: HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007, 21: 1263-1272. 10.1097/QAD.0b013e3281864667.
Saba E, Grivel JC, Vanpouille C, Brichacek B, Fitzgerald W, Margolis L, Lisco A: HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model. Mucosal Immunol. 2010, 3: 280-290. 10.1038/mi.2010.2.
Sundaravaradan V, Saxena SK, Ramakrishnan R, Yedavalli VR, Harris DT, Ahmad N: Differential HIV-1 replication in neonatal and adult blood mononuclear cells is influenced at the level of HIV-1 gene expression. Proc Natl Acad Sci U S A. 2006, 103: 11701-11706. 10.1073/pnas.0602185103.
Yamamoto T, Tsunetsugu-Yokota Y, Mitsuki YY, Mizukoshi F, Tsuchiya T, Terahara K: Selective transmission of R5 HIV-1 over X4 HIV-1 at the dendritic cell-T cell infectious synapse is determined by the T cell activation state. PLoS Pathog. 2009, 5: e1000279-10.1371/journal.ppat.1000279.
Fiser AL, Lin YL, Portales P, Mettling C, Clot J, Corbeau P: Pairwise comparison of isogenic HIV-1 viruses: R5 phenotype replicates more efficiently than X4 phenotype in primary CD4+ T cells expressing physiological levels of CXCR4. J Acquir Immune Defic Syndr. 53: 162-166.
O'Garra A: Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 1998, 8: 275-283. 10.1016/S1074-7613(00)80533-6.
Clerici M, Shearer GM: A TH1-->TH2 switch is a critical step in the etiology of HIV infection. Immunol Today. 1993, 14: 107-111. 10.1016/0167-5699(93)90208-3.
Sher A, Gazzinelli RT, Oswald IP, Clerici M, Kullberg M, Pearce EJ: Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev. 1992, 127: 183-204. 10.1111/j.1600-065X.1992.tb01414.x.
Sallusto F, Lanzavecchia A, Mackay CR: Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today. 1998, 19: 568-574. 10.1016/S0167-5699(98)01346-2.
Loetscher P, Uguccioni M, Bordoli L, Baggiolini M, Moser B, Chizzolini C, Dayer JM: CCR5 is characteristic of Th1 lymphocytes. Nature. 1998, 391: 344-345. 10.1038/34814.
Sallusto F, Lenig D, Mackay CR, Lanzavecchia A: Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med. 1998, 187: 875-883. 10.1084/jem.187.6.875.
Maggi E, Mazzetti M, Ravina A, Annunziato F, de Carli M, Piccinni MP: Ability of HIV to promote a TH1 to TH0 shift and to replicate preferentially in TH2 and TH0 cells. Science. 1994, 265: 244-248. 10.1126/science.8023142.
Annunziato F, Galli G, Nappi F, Cosmi L, Manetti R, Maggi E: Limited expression of R5-tropic HIV-1 in CCR5-positive type 1-polarized T cells explained by their ability to produce RANTES, MIP-1alpha, and MIP-1beta. Blood. 2000, 95: 1167-1174.
Tanaka Y, Koyanagi Y, Tanaka R, Kumazawa Y, Nishimura T, Yamamoto N: Productive and lytic infection of human CD4+ type 1 helper T cells with macrophage-tropic human immunodeficiency virus type 1. J Virol. 1997, 71: 465-470.
Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S: Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. J Immunol. 2010, 184: 1604-1616. 10.4049/jimmunol.0903058.
Vicenzi E, Bordignon PP, Biswas P, Brambilla A, Bovolenta C, Cota M: Envelope-dependent restriction of human immunodeficiency virus type 1 spreading in CD4(+) T lymphocytes: R5 but not X4 viruses replicate in the absence of T-cell receptor restimulation. J Virol. 1999, 73: 7515-7523.
Arthos J, Rubbert A, Rabin RL, Cicala C, Machado E, Wildt K: CCR5 signal transduction in macrophages by human immunodeficiency virus and simian immunodeficiency virus envelopes. J Virol. 2000, 74: 6418-6424. 10.1128/JVI.74.14.6418-6424.2000.
Weissman D, Rabin RL, Arthos J, Rubbert A, Dybul M, Swofford R: Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor. Nature. 1997, 389: 981-985. 10.1038/40173.
Liu QH, Williams DA, McManus C, Baribaud F, Doms RW, Schols D: HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation. Proc Natl Acad Sci U S A. 2000, 97: 4832-4837. 10.1073/pnas.090521697.
Kinter AL, Poli G, Maury W, Folks TM, Fauci AS: Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells. J Virol. 1990, 64: 4306-4312.
El Hed A, Khaitan A, Kozhaya L, Manel N, Daskalakis D, Borkowsky W: Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection. J Infect Dis. 2010, 201: 843-854. 10.1086/651021.
Ancuta P, Monteiro P, Sekaly RP: Th17 lineage commitment and HIV-1 pathogenesis. Curr Opin HIV AIDS. 2010, 5: 158-165. 10.1097/COH.0b013e3283364733.
Kanwar B, Favre D, McCune JM: Th17 and regulatory T cells: implications for AIDS pathogenesis. Curr Opin HIV AIDS. 5: 151-157. 10.1097/COH.0b013e328335c0c1.
Kornfeld C, Ploquin MJ, Pandrea I, Faye A, Onanga R, Apetrei C: Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS. J Clin Invest. 2005, 115: 1082-1091.
Nigam P, Velu V, Kannanganat S, Chennareddi L, Kwa S, Siddiqui M, Amara RR: Expansion of FOXP3+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control. J Immunol. 184: 1690-1701. 10.4049/jimmunol.0902955.
Schuitemaker H, Kootstra NA, de Goede RE, de Wolf F, Miedema F, Tersmette M: Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture. J Virol. 1991, 65: 356-363.
Cicala C, Arthos J, Ruiz M, Vaccarezza M, Rubbert A, Riva A: Induction of phosphorylation and intracellular association of CC chemokine receptor 5 and focal adhesion kinase in primary human CD4+ T cells by macrophage-tropic HIV envelope. J Immunol. 1999, 163: 420-426.
Davis CB, Dikic I, Unutmaz D, Hill CM, Arthos J, Siani MA: Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5. J Exp Med. 1997, 186: 1793-1798. 10.1084/jem.186.10.1793.
Guntermann C, Murphy BJ, Zheng R, Qureshi A, Eagles PA, Nye KE: Human immunodeficiency virus-1 infection requires pertussis toxin sensitive G-protein-coupled signalling and mediates cAMP downregulation. Biochem Biophys Res Commun. 1999, 256: 429-435. 10.1006/bbrc.1999.0333.
Cicala C, Arthos J, Selig SM, Dennis G, Hosack DA, Van Ryk D: HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. Proc Natl Acad Sci U S A. 2002, 99: 9380-9385. 10.1073/pnas.142287999.
Cicala C, Arthos J, Martinelli E, Censoplano N, Cruz CC, Chung E: R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells. Proc Natl Acad Sci U S A. 2006, 103: 3746-3751. 10.1073/pnas.0511237103.
Cicala C, Arthos J, Censoplano N, Cruz C, Chung E, Martinelli E: HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells. Virology. 2006, 345: 105-114. 10.1016/j.virol.2005.09.052.
Yoder A, Yu D, Dong L, Iyer SR, Xu X, Kelly J: HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells. Cell. 2008, 134: 782-792. 10.1016/j.cell.2008.06.036.
Alfano M, Rizzi C, Corti D, Adduce L, Poli G: Bacterial toxins: potential weapons against HIV infection. Curr Pharm Des. 2005, 11: 2909-2926. 10.2174/1381612054546725.
Alfano M, Schmidtmayerova H, Amella CA, Pushkarsky T, Bukrinsky M: The B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains. J Exp Med. 1999, 190: 597-605. 10.1084/jem.190.5.597.
Lu Z, Berson JF, Chen Y, Turner JD, Zhang T, Sharron M: Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains. Proc Natl Acad Sci U S A. 1997, 94: 6426-6431. 10.1073/pnas.94.12.6426.
Amara A, Vidy A, Boulla G, Mollier K, Garcia-Perez J, Alcami J: G protein-dependent CCR5 signaling is not required for efficient infection of primary T lymphocytes and macrophages by R5 human immunodeficiency virus type 1 isolates. J Virol. 2003, 77: 2550-2558. 10.1128/JVI.77.4.2550-2558.2003.
Lin YL, Mettling C, Portales P, Reant B, Clot J, Corbeau P: G-protein signaling triggered by R5 human immunodeficiency virus type 1 increases virus replication efficiency in primary T lymphocytes. J Virol. 2005, 79: 7938-7941. 10.1128/JVI.79.12.7938-7941.2005.
Kinter AL, Poli G, Fox L, Hardy E, Fauci AS: HIV replication in IL-2-stimulated peripheral blood mononuclear cells is driven in an autocrine/paracrine manner by endogenous cytokines. J Immunol. 1995, 154: 2448-2459.
Kinter AL, Umscheid CA, Arthos J, Cicala C, Lin Y, Jackson R: HIV envelope induces virus expression from resting CD4+ T cells isolated from HIV-infected individuals in the absence of markers of cellular activation or apoptosis. J Immunol. 2003, 170: 2449-2455.
Popik W, Hesselgesser JE, Pitha PM: Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway. J Virol. 1998, 72: 6406-6413.
Grainger DJ, Lever AM: Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction. Retrovirology. 2005, 2: 23-10.1186/1742-4690-2-23.