Astrocytoma with pilomyxoid features presenting in an adult

Neuropathology - Tập 26 Số 1 - Trang 89-93 - 2006
Ricardo J. Komotar1, J Mocco2, Brad E. Zacharia3, David A. Wilson2, Peter Kim2, Peter Canoll2, Robert Goodman2
1Department of Neurological Surgery, College of Physicians and Surgeons, Columbia University, New York, NY, USA
2Columbia University
3Departments of Neurological Surgery

Tóm tắt

Pilomyxoid histology is presently considered to occur in pediatric brain tumors. We report an astrocytoma with pilomyxoid features presenting in an adult and discuss its relationship to both the established childhood pilomyxoid astrocytoma (PMA) and recently reported tanycytoma. A 28‐year‐old man with medically intractable seizures presented for surgical evaluation. MRI revealed a discrete lesion in the right amygdala/uncus region. The patient elected for craniotomy with stereotactic temporal lobe resection and excision of the lesion. Postoperatively, the patient has done well. At 30‐month follow up, he is seizure free and without evidence of tumor recurrence. We report an astrocytoma with pilomyxoid features presenting in an adult, illustrating that while this histological pattern is most commonly seen in children, it may also affect older individuals. Recognition of this enigmatic pattern in adult gliomas expands the currently accepted epidemiology for this lesion.

Từ khóa


Tài liệu tham khảo

10.1097/00005072-199910000-00004

10.1227/01.NEU.0000097266.89676.25

10.1002/1097-0142(197712)40:6<3123::AID-CNCR2820400656>3.0.CO;2-6

10.3171/jns.1988.69.2.0171

10.1097/00005072-199605000-00204

10.1097/00005072-199905000-00015

Janisch W, 1985, Diencephalic pilocytic astrocytoma with clinical onset in infancy. Biological behavior and pathomorphological findings in 11 children (in German), Zentralbl Allg Pathol, 130, 31

10.1159/000121218

Fuller CE, 2001, Suprasellar monomorphous pilomyxoid neoplasm: an ultastructural analysis, Clin Neuropathol, 20, 256

Lieberman KA, 2003, Tanycytomas: a newly characterized hypothalamic‐suprasellar and ventricular tumor, AJNR Am J Neuroradiol, 24, 1999

Thông tin
Thông tin xuất bản

Neuropathology

Tập 26 Số 1

89-93

Thông tin tác giả