Mối liên hệ giữa cô lập xã hội trực tiếp và gián tiếp với tỷ lệ tử vong do tất cả các nguyên nhân và do nguyên nhân cụ thể: Theo dõi 13 năm trong Nghiên cứu Cohort Biobank Quảng Châu
Tóm tắt
Mặc dù cô lập xã hội đã được liên kết với nguy cơ tử vong cao hơn, nhưng vẫn chưa có nhiều thông tin về tác động khác nhau tiềm ẩn của cô lập trực tiếp và không trực tiếp tới tỷ lệ tử vong. Chúng tôi đã nghiên cứu mối liên hệ theo chiều dọc của bốn loại cô lập xã hội, bao gồm cô lập trực tiếp với người cùng sống và người không cùng sống, cô lập không trực tiếp, và cô lập trong câu lạc bộ/tổ chức, đối với tỷ lệ tử vong do tất cả các nguyên nhân và tỷ lệ tử vong do nguyên nhân cụ thể một cách riêng biệt.
Nghiên cứu cohort theo phương pháp tiềm năng này bao gồm 30,430 người lớn trong Nghiên cứu Cohort Biobank Quảng Châu (GBCS), những người đã được tuyển chọn trong giai đoạn 2003–2008 và được theo dõi đến tháng 12 năm 2019.
Trong thời gian theo dõi trung bình 13.2 năm, 4933 ca tử vong đã xảy ra trong 396,466 năm người. Những người tham gia sống một mình có nguy cơ tử vong do tất cả các nguyên nhân (tỷ lệ nguy cơ đã điều chỉnh (AHR) 1.24; khoảng tin cậy (CI) 95% 1.04-1.49) và tử vong do bệnh tim mạch (CVD) (1.61; 1.20–2.03) cao hơn so với những người có ≥ 3 lần tiếp xúc với người cùng sống sau khi đã điều chỉnh cho mười ba yếu tố gây nhiễu tiềm ẩn. So với những người có ≥ 1 lần/tháng tiếp xúc không phải người cùng sống, những người không có tiếp xúc như vậy có nguy cơ tử vong do tất cả các nguyên nhân (1.60; 1.20–2.00) và CVD (1.91; 1.20–2.62) cao hơn. AHR tương ứng (CI 95%) ở những người tham gia không có tiếp xúc qua điện thoại/mail là 1.27 (1.14–1.42) cho tỷ lệ tử vong do tất cả các nguyên nhân, 1.30 (1.08–1.56) cho CVD, và 1.37 (1.12–1.67) cho tử vong do nguyên nhân khác. Tuy nhiên, không tìm thấy mối liên hệ nào của việc tiếp xúc trong câu lạc bộ/tổ chức với tỷ lệ tử vong trên và cũng không có mối quan hệ nào của cả bốn loại cô lập với tử vong do ung thư.
Từ khóa
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