Association Between Medication Supplies and Healthcare Costs in Older Adults from an Urban Healthcare System

Journal of the American Geriatrics Society - Tập 48 Số 7 - Trang 760-768 - 2000
Kevin T. Stroupe1,2,3, Michael D. Murray4,5, Timothy E. Stump6, Christopher M. Callahan7,8
1Dr. Stroupe was formerly a Research Economist at the Regenstrief Institute for Health Care, Indianapolis, Indiana.
2Institute for Health Services Research and Policy Studies, Northwestern University, Evanston, Illinois
3Midwest Center for Health Services and Policy Research and Cooperative Studies Program Coordinating Center, Hines VA Hospital, Hines, Illinois
4School of Pharmacy, Purdue University, Lafayette, Indiana
5the Regenstrief Institute, Indianapolis, Indiana.
6The Regenstrief Institute and the Indiana University Center for Aging Research, Indianapolis, Indiana.
7Regenstrief Institute, Indianapolis, Indiana.
8School of Medicine, Indiana University, and Director of the Indiana University Center for Aging Research, Indianapolis, Indiana

Tóm tắt

OBJECTIVES: The amount of medication dispensed to older adults for the treatment of chronic disease must be balanced carefully. Insufficient medication supplies lead to inadequate treatment of chronic disease, whereas excessive supplies represent wasted resources and the potential for toxicity. We used an electronic medical record system to determine the distribution of medications supplied to older urban adults and to examine the correlations of these distributions with healthcare costs and use.DESIGN: A cross‐sectional study using data acquired over 3 years (1994–1996).SETTING: A tax‐supported urban public healthcare system consisting of a 300‐bed hospital, an emergency department, and a network of community‐based ambulatory care centers.PATIENTS: Patients were >60 years of age and had at least one prescription refill and at least two ambulatory visits or one hospitalization during the 3‐year period.MEASUREMENTS: Focusing on 12 major categories of drugs used to treat chronic diseases, we determined the amounts and direct costs of these medications dispensed to older adult patients. Amounts of medications that were needed by patients to medicate themselves adequately were compared with the medication supply actually dispensed considering all sources of care (primary, emergency, and inpatient). We calculated the excess drug costs attributable to oversupply of medication (>120% of the amount needed) and the drug cost reduction caused by undersupply of medication (<80% of the amount needed). We also compared total healthcare use and costs for patients who had an over‐supply, an undersupply, or an appropriate supply of their medications.RESULTS: The cohort comprised 4164 patients with a mean age of 71 ± 7 (SD) who received a mean of 3 ± 2 (SD) drugs for chronic conditions. There were 668 patients (16%) who received <80% of the supply needed, 1556 patients (37%) who received between 80 and 120% of the supply needed, and 1940 patients (47%) who received >120% of the supply needed. The total direct cost of targeted medications for 3 years was $1.96 million or, on average, $654,000 annually. During the 3‐year period, patients receiving >120% of their needed medications had excess direct medication costs of $279,084 or $144 per patient, whereas patients receiving <80% of drugs needed had reduced medication costs of $423,438 or $634 per patient. Multivariable analyses revealed that both under‐ and over‐supplies of medication were associated with a greater likelihood of emergency department visits and hospital admissions.CONCLUSIONS: More than one‐half of the older adults in our study have under‐ or over‐supplies of medications for the treatment of their chronic diseases. Such inappropriate supplies of medications are associated with healthcare utilization and costs. J Am Geriatr Soc 48:760–768, 2000.

Từ khóa


Tài liệu tham khảo

10.1177/109019819302000409

Sclar DA, 1991, Effect of health education in promoting prescription refill compliance among patients with hypertension, Clin Ther, 13, 489

10.1001/jama.1996.03540180029029

Cohen RA, Chartbook on Health Data on Older Americans: United States, 1992, Vital and Health Statistics, 93

10.1177/106002808501901024

10.1111/j.1532-5415.1986.tb06332.x

10.1111/j.1532-5415.1988.tb04405.x

10.1001/archinte.1990.00390160093019

Bond WS, 1991, Detection methods and strategies for improving medication compliance, Am J Hosp Pharm, 48, 1978

10.1016/0002-9149(93)90014-4

Salzman C., 1995, Medication compliance in the elderly, J Clin Psychiatry, 56, 18

10.1007/s002280050358

10.1136/bmj.1.6008.505

Larrat EP, 1990, Compliance‐related problems in the ambulatory population, Am Pharm, 18, 10.1016/S0160-3450(15)31554-3

Cluff L., 1985, Patient compliance: Changing patterns of disease and health care costs, Hosp Formul, 20, 503

10.1001/jama.1993.03510180077038

10.1001/jama.279.18.1458

10.1001/archinte.1994.00420040107014

10.1007/BF02600534

Hamilton RA, 1992, Use of prescription‐refill records to assess patient compliance, Am J Hosp Pharm, 49, 1691

10.1016/S1386-5056(99)00009-X

10.1111/j.1532-5415.1998.tb06003.x

10.1097/00005650-199907000-00006

10.1136/jamia.1998.0050546

10.1097/00005650-198206000-00006

Klein LE, 1984, Medication problems among outpatients A study with emphasis on the elderly, Arch Intern Med, 144, 1185, 10.1001/archinte.1984.00350180105016

10.1093/geronj/42.5.552

10.1038/clpt.1989.122

10.2105/AJPH.86.12.1805

10.1097/00005650-199711000-00008

Powell KM, 1995, Failure of educational videotapes to improve medication compliance in a health maintenance organization, Am J Health Syst Pharm, 52, 2196, 10.1093/ajhp/52.20.2196

10.7326/0003-4819-127-8_Part_2-199710151-00063

10.1177/106002808602000210

10.1097/00005650-199909000-00002

Herbert PR, 1997, Cholesterol lowering with statin drugs, risk of stroke, and total mortality, JAMA, 278, 313, 10.1001/jama.1997.03550040069040