Association Between Inflammatory Potential of the Diet and Ulcerative Colitis: A Case-Control Study

Frontiers in Nutrition - Tập 7
Zeinab Khademi1,2, Parvane Saneei3,4, Ammar Hassanzadeh Keshteli5,6, Hamed Daghaghzadeh6, Hamid Tavakkoli6, Peyman Adibi6, Ahmad Esmaillzadeh3,1,7
1Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Iran
2Students' Scientific Research Center, Tehran University of Medical Sciences, Iran
3Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Iran
4Food Security Research Center, Isfahan University of Medical Sciences, Iran
5Department of Medicine, University of Alberta, Canada
6Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Iran
7Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular -Cellular Sciences Institute, Tehran University of Medical Sciences, Iran

Tóm tắt

Background/Aim:Despite the inflammatory nature of inflammatory bowel disease (IBD), limited data are available on the association of inflammatory potential of the diet and risk of ulcerative colitis (UC). We aimed to investigate the association of inflammatory potential of the diet (IPD) score and odds of UC in a case-control study.Methods:Patients with UC were enrolled from Iranian IBD registry, whose disease was confirmed by a gastroenterologist. Controls were selected randomly from the Study of the Epidemiology of Psycho Alimentary Health and Nutrition (SEPAHAN) study, a large population-based study on more than 8,000 apparently healthy individuals. Dietary intakes of 28 food items obtained from a validated dish-based food frequency questionnaire (FFQ), were used to compute IPD score.Results:This case-control study was carried out among 109 cases and 218 randomly chosen controls. Mean age of cases and controls was 39.5 ± 10.0 and 41.5 ± 11.8 y, respectively. Totally, 52% of study participants were female and 48% were male. After controlling for age, sex, and body mass index (BMI), we found that the patients with UC were more likely to be in the highest quartile of IPD score compared with controls (OR: 2.83; 95% CI: 1.41–5.69,P-trend < 0.001). This association strengthened after additional adjustment for education, smoking, medical history, and physical activity (OR: 3.48; 95% CI: 1.32–9.10,P-trend = 0.003). When we took dietary habits into account, the association was slightly attenuated (OR: 3.33; 95% CI: 1.20–9.20,P-trend = 0.005).Conclusions:We found that adherence to a pro-inflammatory diet was positively associated with greater odds of UC. Further studies are required to confirm these findings.

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Tài liệu tham khảo

Rogler, 2018, New insights into the pathophysiology of inflammatory bowel disease: microbiota, epigenetics and common signalling pathways, Swiss Med Wkly., 148, w14599, 10.4414/smw.2018.14599

Zhou, 2017, New frontiers in genetics, gut microbiota, and immunity: a rosetta stone for the pathogenesis of inflammatory bowel disease, Biomed Res Int., 2017, 8201672, 10.1155/2017/8201672

Abraham, 2009, Inflammatory bowel disease, N Engl J Med., 361, 2066, 10.1056/NEJMra0804647

Khor, 2011, Genetics and pathogenesis of inflammatory bowel disease, Nature., 474, 307, 10.1038/nature10209

Malekzadeh, 2016, Emerging epidemic of inflammatory bowel disease in a middle income country: a nation-wide study from Iran, Arch Iran Med., 19, 2

Asakura, 2008, Is there a link between food and intestinal microbes and the occurrence of Crohn's disease and ulcerative colitis?, J Gastroenterol Hepatol., 23, 1794, 10.1111/j.1440-1746.2008.05681.x

Ruemmele, 2016, Role of diet in inflammatory bowel disease, Ann Nutr Metab., 68, 33, 10.1159/000445392

Santos, 2013, Systematic review of saturated fatty acids on inflammation and circulating levels of adipokines, Nutr Res., 33, 687, 10.1016/j.nutres.2013.07.002

Bordoni, 2017, Dairy products and inflammation: a review of the clinical evidence, Crit Rev Food Sci Nutr., 57, 2497, 10.1080/10408398.2014.967385

Rizzello, 2019, Implications of the Westernized diet in the onset and progression of IBD, Nutrients., 11, 1033, 10.3390/nu11051033

Whalen, 2016, Paleolithic and mediterranean diet pattern scores are inversely associated with biomarkers of inflammation and oxidative balance in adults123, J Nutr., 146, 1217, 10.3945/jn.115.224048

Shivappa, 2014, A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS), Public Health Nutr., 17, 1825, 10.1017/s136898001300.2565

Tabung, 2015, Construct validation of the dietary inflammatory index among postmenopausal women, Ann Epidemiol., 25, 398, 10.1016/j.annepidem.2015.03.009

Ruiz-Canela, 2015, Dietary inflammatory index and anthropometric measures of obesity in a population sample at high cardiovascular risk from the PREDIMED (PREvencion con DIeta MEDiterranea) trial, Br J Nutr., 113, 984, 10.1017/s0007114514004401

Shivappa, 2014, Designing and developing a literature-derived, population-based dietary inflammatory index, Public Health Nutr., 17, 1689, 10.1017/S1368980013002115

Cavicchia, 2009, A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein, J Nutr., 139, 2365, 10.3945/jn.109.114025

Salari-Moghaddam, 2019, Empirically derived food-based inflammatory potential of the diet, irritable bowel syndrome and its severity, Nutrition., 64, 141, 10.1016/j.nut.2019.02.004

Shivappa, 2017, Dietary inflammatory index and risk of reflux oesophagitis, Barrett's oesophagus and oesophageal adenocarcinoma: a population-based case-control study, Br J Nutr., 117, 1323, 10.1017/s0007114517001131

Shivappa, 2016, Inflammatory potential of diet and risk of ulcerative colitis in a case-control study from Iran, Nutr Cancer., 68, 404, 10.1080/01635581.2016.1152385

Adibi, 2012, The study on the epidemiology of psychological, alimentary health and nutrition (SEPAHAN): overview of methodology, J Res Med Sci., 17, S292

Keshteli, 2014, A Dish-based Semi-quantitative food frequency questionnaire for assessment of dietary intakes in epidemiologic studies in Iran: design and development, Int J Prev Med., 5, 29

Farhangi, 2018, Dietary inflammatory index: a potent association with cardiovascular risk factors among patients candidate for coronary artery bypass grafting (CABG) surgery, Nutrition J., 17, 20, 10.1186/s12937-018-0325-2

Lennard-Jones, 1989, Classification of inflammatory bowel disease, Scand J Gastroenterol Suppl., 170, 2, 10.3109/00365528909091339

Aminianfar, 2019, Validity of self-reported height, weight, body mass index and waist circumference in Iranian adults, Int J Prev Med.

Kimiagar, 1998, Food consumption pattern in the Islamic Republic of Iran and its relation to coronary heart disease, East Mediterr Health J., 4, 539, 10.26719/1998.4.3.539

Windsor, 2019, Evolving epidemiology of IBD, Curr Gastroenterol Rep., 21, 40, 10.1007/s11894-019-0705-6

Cui, 2018, A systematic review of epidemiology and risk factors associated with chinese inflammatory bowel disease, Front Med., 5, 183, 10.3389/fmed.2018.00183

Defagó, 2014, Influence of food patterns on endothelial biomarkers: a systematic review, J Clin Hypertens., 16, 907, 10.1111/jch.12431

Li, 2015, Consumption of vegetables and fruit and the risk of inflammatory bowel disease: a meta-analysis, Eur J Gastroenterol Hepatol., 27, 623, 10.1097/MEG.0000000000000330

Buyken, 2014, Association between carbohydrate quality and inflammatory markers: systematic review of observational and interventional studies, Am J Clin Nutr., 99, 813, 10.3945/ajcn.113.074252

Lopez-Garcia, 2004, Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction, Am J Clin Nutr., 80, 1029, 10.1093/ajcn/80.4.1029

Shivappa, 2018, Association of pro-inflammatory diet with low-grade inflammation: results from the Moli-sani study, Nutrition., 54, 182, 10.1016/j.nut.2018.04.004

Rahmani, 2019, Healthy Eating Index-2015 as a predictor of ulcerative colitis risk in a case–control cohort, J Dig Dis., 20, 649, 10.1111/1751-2980.12826

Rahmani, 2019, Dietary total antioxidant capacity and risk of ulcerative colitis: a case-control study, J Dig Dis., 20, 636, 10.1111/1751-2980.12823

Lo, 2020, Dietary inflammatory potential and risk of Crohn's Disease and Ulcerative Colitis, Gastroenterology., 159, 873, 10.1053/j.gastro.2020.05.011

Shivappa, 2017, Association between dietary inflammatory index and inflammatory markers in the HELENA study, Mol Nutr Food Res., 61, 707, 10.1002/mnfr.201600707

Shivappa, 2017, Association between the dietary inflammatory index (DII) and telomere length and C-reactive protein from the National Health and Nutrition Examination Survey-1999–2002, Mol Nutr Food Res., 61, 1600630, 10.1002/mnfr.201600630

Padin, 2019, A proinflammatory diet is associated with inflammatory gene expression among healthy, non-obese adults: can social ties protect against the risks?, Brain Behav Immun., 82, 36, 10.1016/j.bbi.2019.07.031

Witkowski, 2018, Recipe for IBD: can we use food to control inflammatory bowel disease?, Semin Immunopathol., 40, 145, 10.1007/s00281-017-0658-5

Kunnumakkara, 2018, Chronic diseases, inflammation, and spices: how are they linked?, J Trans Med., 16, 14, 10.1186/s12967-018-1381-2

Minihane, 2015, Low-grade inflammation, diet composition and health: current research evidence and its translation, Br J Nutr., 114, 999, 10.1017/s0007114515002093

Castro, 2019, Dietary composition and effects in inflammatory bowel disease, Nutrients., 11, 1398, 10.3390/nu11061398

Rapozo, 2017, Diet and microbiota in inflammatory bowel disease: the gut in disharmony, World J Gastroenterol., 23, 2124, 10.3748/wjg.v23.i12.2124

Weng, 2019, Diet-microbiota-metabolite interaction networks reveal key players in inflammatory bowel disease, J Dig Dis., 20, 447, 10.1111/1751-2980.12795

Vahid, 2018, Validation of a dietary inflammatory index (DII) and association with risk of gastric cancer: a case-control study, Asian Pac J Cancer Prev., 19, 1471, 10.22034/apjcp.2018.19.6.1471

Vahid, 2017, Association between Maternal Dietary Inflammatory Index (DII) and abortion in Iranian women and validation of DII with serum concentration of inflammatory factors: case-control study, Appl Physiol Nutr Metab., 42, 511, 10.1139/apnm-2016-0274

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Frontiers in Nutrition

Tập 7

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