Assessment of genotoxicity of Lidocaine®, Prilonest® and Septanest® in the drosophila wing-spot test

Food and Chemical Toxicology - Tập 47 - Trang 205-208 - 2009
L.E. Schneider1, V.S. do Amaral1, R.R. Dihl1, M. Lehmann1, M.L. Reguly1, H.H.R. de Andrade1
1Laboratório da Toxicidade Genética (TOXIGEN), Programa de Pós-Graduação em Genética e Toxicologia Aplicada (PPGGTA), Universidade Luterana do Brasil (ULBRA), Predio 22, 4° andar, Sala 25, Av. Farroupilha 8001, 92425-900 Canoas, RS, Brazil

Tài liệu tham khảo

Abraham, 1996, Protection by coffee against somatic genotoxicity in Drosophila: role of bioactivation capacity, Food Chem. Toxicol., 34, 1, 10.1016/0278-6915(95)00087-9 Andrade, 2004, Wing somatic mutation and recombination test (SMART), 389 Aoyama, 1989, Cytochrome P450 hPCN3, a novel cytochrome P450 IIIA gene product that is differentially expressed in adult human liver, J. Biol. Chem., 264, 10388, 10.1016/S0021-9258(18)81632-5 Bishop, 2001, Homologous recombination as mechanism of carcinogenesis, Biochim. Biophys. Acta, 1471, 109 Bishop, 2003, Role of homologous recombination in carcinogenesis, Exp. Mol. Pathol., 74, 94, 10.1016/S0014-4800(03)00010-8 Bryant, 1994, 2, 6–Dimethylaniline–hemoglobin adducts from lidocaine in humans, Carcinogenesis, 15, 2287, 10.1093/carcin/15.10.2287 Dapkus, 1977, Chromosomal analysis of DDT-resistance in a long-term selected population of Drosophila melanogaster, Genetics, 87, 685, 10.1093/genetics/87.4.685 Frei, 1988, Statistical methods to decide whether mutagenicity data from Drosophila assays indicate a positive, negative or inconclusive result, Mutat. Res., 203, 297, 10.1016/0165-1161(88)90019-2 Frei, 1995, Optimal experimental design and sample size for the statistical evaluation of data from somatic mutation and recombination tests (SMART) in Drosophila, Mutat. Res., 334, 247, 10.1016/0165-1161(95)90018-7 Graf, 1984, Somatic mutation and recombination test in Drosophila melanogaster, Environ. Mol. Mutagen., 6, 153, 10.1002/em.2860060206 Graf, 1989, Thirty compounds in the Drosophila wing spot test, Mutat. Res., 222, 359, 10.1016/0165-1218(89)90112-2 Graf, 1998, Antigenotoxicity studies in Drosophila melanogaster, Mutat. Res., 402, 203, 10.1016/S0027-5107(97)00298-4 Hagiwara, 2006, Assessment of genotoxicity of 14 chemical agents used in dental practice. Ability to induce chromosome aberrations in Syrian hamster embryo cells, Mutat. Res., 603, 111, 10.1016/j.mrgentox.2005.08.011 Hällstrom, 1985, Genetic regulation of the cytochrome P-450 system in Drosophila melanogaster. I. Chromosomal determination of some cytochrome P-450 dependent reactions, Chem. Bio. Interact., 56, 157, 10.1016/0009-2797(85)90003-1 Ishidate, 1988, A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures, Mutat. Res., 145, 151, 10.1016/0165-1110(88)90023-1 Itoh, 1994, A novel form of mouse cytochrome-P4503A (cyp3A–16). Its cDNA cloning and expression in fetal liver, Eur. J. Biochem., 226, 877, 10.1111/j.1432-1033.1994.t01-1-00877.x Kastenbaum, 1970, Tables to determining the statistical significance of mutation frequencies, Mutat. Res., 9, 527, 10.1016/0027-5107(70)90038-2 Kayukawa, 1988, Cytotoxicity, genotoxicity and carcinogenicity of local anesthetics to cultured Syrian hamster embryo cell, Odontology, 76, 941 Leuschner, 1999, Studies on the toxicological profile of the local anaesthetic articaine, Arzneim-Forsch/Drug Res., 49, 126 Lindsley, 1992 Nakamura, 1999, Prilocaine induces apoptosis in osteoblastic cells, Canadian J. Anesthesiol., 46, 476, 10.1007/BF03012949 Ramel, 1988, Short-term testing- are we looking at wrong endpoint?, Mutat. Res., 205, 13, 10.1016/0165-1218(88)90004-3 Saner, 1996, Metabolism of promutagens catalyzed by Drosophila melanogaster CYP6A2 enzyme in Saccharomyces cerevisiae, Environ. Mol. Mutagen., 27, 46, 10.1002/(SICI)1098-2280(1996)27:1<46::AID-EM7>3.0.CO;2-C Sinigaglia, 2004, Effect of vanillin on toxicant-induced mutation and mitotic recombination in proliferating somatic cells of Drosophila melanogaster, Environ. Mol. Mutagen., 44, 394, 10.1002/em.20067 Sinigaglia, 2006, Vanillin as a modulator agent in SMART test: inhibition in the steps that precede N-methyl-N-nitrosourea-, N-ethyl-N-nitrosoure- ethylmethanesulphonate- and bleomycin-genotoxicity, Mutat. Res., 607, 225, 10.1016/j.mrgentox.2006.04.012 Vogel, 1999, The results of assays in Drosophila as indicators of exposure to carcinogens, 427