Assessment and Etiology of Attention Deficit Hyperactivity Disorder and Oppositional Defiant Disorder in Boys and Girls

Behavior Genetics - Tập 37 - Trang 559-566 - 2007
Eske M. Derks1, Conor V. Dolan2, Jim J. Hudziak3, Michael C. Neale1,4, Dorret I. Boomsma1
1Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands
2Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
3Department of Psychiatry and Medicine, Division of Human Genetics, Center for Children, Youth and Families, College of Medicine, University of Vermont, Burlington, USA
4Department of Psychiatry and Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA

Tóm tắt

Attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are more common in boys than girls. In this paper, we investigated whether the prevalence differences are attributable to measurement bias. In addition, we examined sex differences in the genetic and environmental influences on variation in these behaviors. Teachers completed the Conners Teacher Rating Scale-Revised:Short version (CTRS-R:S) in a sample of 800 male and 851 female 7-year-old Dutch twins. No sex differences in the factor structure of the CTRS-R:S were found, implying the absence of measurement bias. The heritabilities for both ADHD and ODD were high and were the same in boys and girls. However, partly different genes are expressed in boys and girls.

Tài liệu tham khảo

American Psychiatric Association (1994) Task force on DSM-IV. Diagnostic and statistical manual of mental disorder: DSM-IV, 4th edn. American Psychiatric Association, Washington, DC Bentler PM (1995) EQS structural equations program manual. Multivariate Software, Encino, CA Biederman J, Mick E, Faraone SV, Braaten E, Doyle A, Spencer T et al (2002) Influence of gender on attention deficit hyperactivity disorder in children referred to a psychiatric clinic. Am J Psychiatry 159:36–42 Bock RD, Aitkin M (1981) Marginal maximum likelihood estimation of item parameters: application of an EM algorithm. Psychometrika 46:443–459 Boomsma DI, Geus de EJC, Vink JM, Stubbe JH, Distel MA, Hottenga JJ, Posthuma D, van Beijsterveldt CEM, Hudziak JJ, Bartels M, Willemsen G (2006) Netherlands Twin Register: from twins to twin families. Twin Res Hum Genet 9(6):849–857 Boomsma DI, Vink JM, van Beijsterveldt CEM, Geus EJC, Beem AL, Mulder EJCM et al (2002) Netherlands Twin Register: a focus on longitudinal research. Twin Res 5:1–6 Browne MW, MacCallum RC, Kim C, Andersen BL, Glaser R (2002) When fit indices and residuals are incompatible. Psychol Methods 7:403–421 Conners CK (2001) Conners’ rating scales-revised. Multi-Health Systems, Inc., New York Conners CK, Sitarenios G, Parker JDA, Epstein JN (1998) Revision and restandardization of the Conners teacher rating scale (CTRS-R): factor structure, reliability, and criterion validity. J Abnormal Child Psychol 26:279–291 Derks EM, Dolan CV, Boomsma DI (2004) Effects of censoring on parameter estimates and power in genetic modeling. Twin Res 7:659–669 Derks EM, Hudziak JJ, van Beijsterveldt CEM, Dolan CV, Boomsma DI (in press) Genetic analyses of maternal and teacher ratings on attention problems in 7-year-old Dutch twins. Behav Genet Dolan CV (1994) Factor analysis of variables with 2, 3, 5 and 7 response categories: a comparison of categorical variable estimators using simulated data. Br J Math Stat Psychol 47:309–326 Fantuzzo J, Grim S, Mordell M, McDermott P, Miller L, Coolahan K (2001) A multivariate analysis of the revised Conners teacher rating scale with low-income, urban preschool children. J Abnormal Child Psychol 29:141–152 Gaub M, Carlson CL (1997) Gender differences in ADHD: a meta-analysis and critical review. J Am Acad Child Adolescent Psychiatry 36:1036–1045 Hu L, Bentler PM (1999) Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Eq Model 6:1–55 Hudziak JJ, Derks EM, Althoff RR, Copeland WM, Boomsma DI (2005) The genetic and environmental contributions to oppositional defiant behavior: a multi-informant twin study. J Am Acad Child Adolescent Psychiatry 44:907–914 Jöreskog KG, Sörbom D (1996) PRELIS 2 user’s reference guide. Scientific Software International, Chicago Levy F, Hay DA, Bennett KS, McStephen M (2005) Gender differences in ADHD subtype comorbidity. J Am Acad Child Adolescent Psychiatry 44:368–376 Loeber R, Burke JD, Lahey BB, Winters A, Zera M (2000) Oppositional defiant and conduct disorder: a review of the past 10 years, part I. J Am Acad Child Adolescent Psychiatry 39:1468–1484 Lubke GH, Dolan CV, Neale MC (2004) Implications of absence of measurement invariance for detecting sex limitation and genotype by environment interaction. Twin Res 7:292–298 Lynch M, Walsh B (1998) Genetics and analysis of quantitative traits. Sinauer, Sunderland, MA Martin N, Scourfield J, McGuffin P (2002) Observer effects and heritability of childhood attention-deficit hyperactivity disorder symptoms. Br J Psychiatry 180:260–265 Maughan B, Rowe R, Messer J, Goodman R, Meltzer H (2004) Conduct disorder and oppositional defiant disorder in a national sample: developmental epidemiology. J Child Psychol Psychiatry 45:609–621 Mellenbergh GJ (1989) Item bias and item response theory. Int J Educ Res 13:127–143 Meredith W (1993) Measurement invariance, factor-analysis and factorial invariance. Psychometrika 58:525–543 Neale MC, Boker SM, Xie G, Maes HH (2003) Mx: statistical modeling, 6th edn. Department of Psychiatry, Richmond, VA van den Oord EJCG, Koot HM, Boomsma DI, Verhulst FC, Orlebeke JF (1995) A twin-singleton comparison of problem behaviour in 2–3-year-olds. J Child Psychol Psychiatry 36:449–458 Rietveld MJH, Hudziak JJ, Bartels M, van Beijsterveldt CEM, Boomsma DI (2004) Heritability of attention problems in children: longitudinal results from a study of twins, age 3 to 12. J Child Psychol Psychiatry 45:577–588 Saudino KJ, Ronald A, Plomin R (2005) The etiology of behavior problems in 7-year-old twins: substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. J Abnormal Child Psychol 33:113–130 Simonoff E, Pickles A, Hervas A, Silberg JL, Rutter M, Eaves L (1998) Genetic influences on childhood hyperactivity: contrast effects imply parental rating bias, not sibling interaction. Psychol Med 28:825–837 Vierikko E, Pulkkinen L, Kaprio J, Rose RJ (2004) Genetic and environmental influences on the relationship between aggression and hyperactivity-impulsivity as rated by teachers and parents. Twin Res 7:261–274