The power of the classical twin study to resolve variation in threshold traits Tập 24 - Trang 239-258 - 1994
Michael C. Neale, Lindon J. Eaves, Kenneth S. Kendler
We explore the power of the twin study to resolve sources of familial
resemblance when the data are measured at the binary or ordinal level. Four
components of variance were examined: additive genetic, nonadditive genetic, and
common and specific environment. Curves are presented to compare the power of
the continuous case with those of threshold models corresponding to different
prevalences in th... hiện toàn bộ
Estimating genetic correlations from inbred strains Tập 11 - Trang 103-114 - 1981
Joseph P. Hegmann, Bernard Possidente
Genetic correlations measure the extent of pleiotropic effects of polygenes on
pairs of characters or the closeness of linkage between sets of loci influencing
the traits and held in allelic (gametic) disequilibrium. Their importance for
research lies primarily in predicting correlated responses of one trait to
selection based on values for another, and secondarily in analyzing the complex
organiz... hiện toàn bộ