Application of methods of identifying receptor binding models and analysis of parameters

Theoretical Biology and Medical Modelling - Tập 1 Số 1 - Trang 1-4 - 2004
Gurevich, Konstantin G1
1UNESCO Chair in healthy life for sustainable development, Moscow State Dentistry Medical University (MSDMU), Moscow, Russia

Tóm tắt

Possible methods for distinguishing receptor binding models and analysing their parameters are considered. The conjugate gradients method is shown to be optimal for solving problems of the kind considered. Convergence with experimental data is rapidly achieved with the appropriate model but not with alternative models. Lack of convergence using the conjugate gradients method can be taken to indicate inconsistency between the receptor binding model and the experimental data. Thus, the conjugate gradients method can be used to distinguish among receptor binding models.

Tài liệu tham khảo

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Theoretical Biology and Medical Modelling

Tập 1 Số 1

1-4

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