Antitumor effects of BMS-777607 on ovarian cancer cells with constitutively activated c-MET

Taiwanese Journal of Obstetrics and Gynecology - Tập 58 - Trang 145-152 - 2019
Chao-Chih Wu1, Chia-Sui Weng2, Yun-Ting Hsu1, Chih-Long Chang1,2,3
1Department of Medical Research, Mackay Memorial Hospital, New Taipei City, Taiwan
2Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan
3Department of Medicine, Mackay Medical College, Sanchi, New Taipei City, Taiwan

Tài liệu tham khảo

Siegel, 2015, Cancer statistics, 2015, CA: Cancer J Clin, 65, 5

Bast, 2009, The biology of ovarian cancer: new opportunities for translation, Nat Rev Cancer, 9, 415, 10.1038/nrc2644

Kobayashi, 2012, Biomarkers for screening, diagnosis, and monitoring of ovarian cancer, Cancer Epidemiol Prev Biomark, 21, 1902, 10.1158/1055-9965.EPI-12-0646

Zhang, 2009, Targeting cancer with small molecule kinase inhibitors, Nat Rev Cancer, 9, 28, 10.1038/nrc2559

Siegel-Lakhai, 2005, Current knowledge and future directions of the selective epidermal growth factor receptor inhibitors erlotinib (Tarceva®) and gefitinib (Iressa®), Oncologist, 10, 579, 10.1634/theoncologist.10-8-579

Ryan, 2008, FDA drug approval summary: lapatinib in combination with capecitabine for previously treated metastatic breast cancer that overexpresses HER-2, Oncologist, 13, 1114, 10.1634/theoncologist.2008-0816

Birchmeier, 2003, Met, metastasis, motility and more, Nat Rev Mol Cell Biol, 4, 915, 10.1038/nrm1261

Sawada, 2007, c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion, Cancer Res, 67, 1670, 10.1158/0008-5472.CAN-06-1147

Ma, 2007, Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion, Br J Cancer, 97, 368, 10.1038/sj.bjc.6603884

Comoglio, 2008, Drug development of MET inhibitors: targeting oncogene addiction and expedience, Nat Rev Drug Discov, 7, 504, 10.1038/nrd2530

Kwon, 2015, Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment, Oncogene, 34, 144, 10.1038/onc.2013.539

Organ, 2011, An overview of the c-MET signaling pathway, Ther Adv Med Oncol, 3, S7, 10.1177/1758834011422556

Lai, 2009, Crosstalk in Met receptor oncogenesis, Trends Cell Biol, 19, 542, 10.1016/j.tcb.2009.07.002

Schroeder, 2009, Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1, 2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily, J Med Chem, 52, 1251, 10.1021/jm801586s

Dai, 2010, BMS-777607, a small-molecule Met kinase inhibitor, suppresses hepatocyte growth factor–stimulated prostate cancer metastatic phenotype in vitro, Mol Cancer Therapeut, 9, 1554, 10.1158/1535-7163.MCT-10-0359

Sharma, 2013, Small-molecule inhibitor BMS-777607 induces breast cancer cell polyploidy with increased resistance to cytotoxic chemotherapy agents, Mol Cancer Therapeut, 12, 725, 10.1158/1535-7163.MCT-12-1079

Toss, 2015, Molecular characterization and targeted therapeutic approaches in breast cancer, Breast Cancer Res, 17, 60, 10.1186/s13058-015-0560-9

Sulpice, 2009, Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells, Biol Cell, 101, 525, 10.1042/BC20080221

Banerjee, 2013, New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential, Clin Cancer Res, 19, 961, 10.1158/1078-0432.CCR-12-2243

Imai, 2006, Comparing antibody and small-molecule therapies for cancer, Nat Rev Cancer, 6, 714, 10.1038/nrc1913

Andrews, 2004, Aurora B regulates MCAK at the mitotic centromere, Dev Cell, 6, 253, 10.1016/S1534-5807(04)00025-5

Hirota, 2005, Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin, Nature, 438, 1176, 10.1038/nature04254

Yan, 2015, The efficacy of synchronous combination of chemotherapy and EGFR TKIs for the first-line treatment of NSCLC: a systematic analysis, PloS One, 10, 10.1371/journal.pone.0135829

Zeng, 2014, Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells, Mol Cancer Therapeut, 13, 37, 10.1158/1535-7163.MCT-13-0242

Schmidt, 1997, Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas, Nat Genet, 16, 68, 10.1038/ng0597-68