Antimicrobial properties of 1‐monoacylglycerols prepared from undecanoic (C11:0) and undecenoic (C11:1) acid

European Journal of Lipid Science and Technology - Tập 112 Số 10 - Trang 1106-1114 - 2010
Magda Janalí­ková1, Rahula Janiš2, Hana Svobodová3, Věra Kašpárková2, Petr Humpolíček4, Jiří Krejčí2
1Department of Food Technology and Microbiology, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka, Zlín, Czech Republic
2Department of Fat, Tenside and Cosmetic Technology, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka, Zlín, Czech Republic
3Department of Environmental Protection Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka, Zlín, Czech Republic
4[Tomas Bata University in Zlin nam. T. G. Masaryka, Zlin, Czech Republic]

Tóm tắt

Abstract

Antimicrobial activity of monoacylglycerols (MAG) with odd number of carbons prepared from undecanoic (MAG C11:0) and undecenoic (MAG C11:1) was investigated. Data showed that both studied substances successfully inhibited Gram‐positive cocci (Staphylococcus aureus) and spore‐forming rods (Bacillus cereus). Gram‐negative bacteria were highly resistant against MAG C11:0 and showed considerable tolerance against MAG C11:1. Minimum inhibitory concentration (MIC) of MAG C11:1 was possible to determine for Escherichia coli only. Complete inhibition of three fungi genera (Alternaria, Cladosporium, Trichothecium) was achieved using MAG C11:1 with a concentration higher than 750 µg/mL. The growth of Aspergillus niger, Mucor racemosus, Phoma, Scopulariopsis, Trichoderma was significantly reduced. Generally, MAG C11:1 was more efficient than MAG C11:0 against all tested microorganisms. Due to a rich production of degradation enzymes, some fungi species surprisingly adapted their metabolism during growth and were even able to utilise tested MAG as a source of carbon.

Practical applications: MAG composed of fatty acids with odd number of carbons in molecule are a promising group of substances applicable in food industry and cosmetics. They represent materials with broad spectrum of antimicrobial activity, especially against Gram‐positive bacteria. More efficient MAG C11:1 with a double bond in molecule can be recommended for reduction of S. aureus that cause food enterotoxicosis.

Từ khóa


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Thông tin xuất bản

European Journal of Lipid Science and Technology

Tập 112 Số 10

1106-1114

Thông tin tác giả