Antifungal 3-Hydroxy Fatty Acids from Lactobacillus plantarum MiLAB14

Applied and Environmental Microbiology - Tập 69 Số 12 - Trang 7554-7557 - 2003
Jörgen Sjögren1,2, Jesper Magnusson3, Anders Broberg1,2, Johan Schnürer3, Lennart Kenne1,2
1Department of Chemis-try, Swedish University of Agricultural Sciences, P.O. Box 7015, SE-750 07 Uppsala, Sweden.
2Department of Chemistry 1 and Department of Microbiology,
3Department of Microbiology, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden

Tóm tắt

ABSTRACT

We report the identification and chemical characterization of four antifungal substances, 3-( R )-hydroxydecanoic acid, 3-hydroxy-5- cis -dodecenoic acid, 3-( R )-hydroxydodecanoic acid and 3-( R )-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 μg ml −1 .

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Applied and Environmental Microbiology

Tập 69 Số 12

7554-7557

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