Đường dẫn truyền tín hiệu của Angiotensin II qua thụ thể AT1: Những hiểu biết mới về cơ chế và bệnh sinh
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Touyz, 2000, Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells, Pharmacol. Rev., 52, 639
Mehta, 2007, Angiotensin II cell signalling: physiological and pathological effects in the cardiovascular system, Am. J. Physiol. Cell Physiol., 292, C82, 10.1152/ajpcell.00287.2006
Griendling, 1997, Angiotensin II signaling in vascular smooth muscle, New concepts. Hypertension, 29, 366
Eguchi, 2003, Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling, Biochem. Soc. Trans., 31, 1198, 10.1042/bst0311198
Yin, 2003, Angiotensin II signaling pathways mediated by tyrosine kinases, Int. J. Biochem. Cell Biol., 35, 780, 10.1016/S1357-2725(02)00300-X
Suzuki, 2005, Recent progress in signal transduction research of the angiotensin II type-1 receptor: protein kinases, vascular dysfunction and structural requirement, Curr. Med. Chem. Cardiovasc. Hematol. Agents, 3, 305, 10.2174/156801605774322355
Ohtsu, 2006, Angiotensin II signal transduction through small GTP-binding proteins: mechanism and significance in vascular smooth muscle cells, Hypertension, 48, 534, 10.1161/01.HYP.0000237975.90870.eb
Gregg, 2003, Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch, Am. J. Physiol. Cell Physiol., 285, C723, 10.1152/ajpcell.00230.2003
Woolfolk, 2005, Angiotensin II-induced activation of p21-activated kinase 1 requires Ca2+ and protein kinase C δ in vascular smooth muscle cells, Am. J. Physiol. Cell Physiol., 289, C1286, 10.1152/ajpcell.00448.2004
Ohtsu, 2006, ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors, Am. J. Physiol. Cell Physiol., 291, C1, 10.1152/ajpcell.00620.2005
Kim, 2006, Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms, Circulation, 113, 1888, 10.1161/CIRCULATIONAHA.105.563213
Feletou, 2006, Endothelial dysfunction: a multifaceted disorder, Am. J. Physiol. Heart Circ. Physiol., 291, H985, 10.1152/ajpheart.00292.2006
Nakashima, 2006, Angiotensin II regulates vascular and endothelial dysfunction: recent topics of Angiotensin II type-1 receptor signaling in the vasculature, Curr. Vasc. Pharmacol., 4, 67, 10.2174/157016106775203126
Touyz, 2005, Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II, Curr. Opin. Nephrol. Hypertens., 14, 125, 10.1097/00041552-200503000-00007
Ruiz-Ortega, 2006, Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases, Nephrol. Dial. Transplant., 21, 16, 10.1093/ndt/gfi265
Ushio-Fukai, 2006, Caveolin-dependent angiotensin II type 1 receptor signaling in vascular smooth muscle, Hypertension, 48, 797, 10.1161/01.HYP.0000242907.70697.5d
Smith, 2006, Signal switching, crosstalk, and arrestin scaffolds: novel G protein-coupled receptor signaling in cardiovascular disease, Hypertension, 48, 173, 10.1161/01.HYP.0000232641.84521.92
Hunyady, 2006, Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II, Mol. Endocrinol., 20, 953, 10.1210/me.2004-0536
de Gasparo, 2000, International Union of Pharmacology. XXIII. The angiotensin II receptors, Pharmacol. Rev., 52, 415
Crowley, 2006, Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney, Proc. Natl. Acad. Sci. U.S.A., 103, 17985, 10.1073/pnas.0605545103
Crowley, 2005, Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system, J. Clin. Invest., 115, 1092, 10.1172/JCI23378
Veerasingham, 2003, Brain renin-angiotensin system dysfunction: recent advances and perspectives, Br. J. Pharmacol., 139, 191, 10.1038/sj.bjp.0705262
Saito, 2001, Transactivation: a novel signaling pathway from angiotensin II to tyrosine kinase receptors, J. Mol. Cell Cardiol., 33, 3, 10.1006/jmcc.2000.1272
Lin, 2003, Transactivation of ErbB1 and ErbB2 receptors by angiotensin II in normal human prostate stromal cells, Prostate, 54, 1, 10.1002/pros.10160
Du, 1996, G-protein and tyrosine kinase receptor cross-talk in rat aortic smooth muscle cells: thrombin- and angiotensin II-induced tyrosine phosphorylation of insulin receptor substrate-1 and insulin-like growth factor 1 receptor, Biochem. Biophys. Res. Commun., 218, 934, 10.1006/bbrc.1996.0165
Eguchi, 1996, Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive tyrosine kinase, J. Biol. Chem., 271, 14169, 10.1074/jbc.271.24.14169
Eguchi, 1998, Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells, J. Biol. Chem., 273, 8890, 10.1074/jbc.273.15.8890
Che, 2002, Angiotensin II triggers EGFR tyrosine kinase-dependent Ca2+ influx in afferent arterioles, Hypertension, 40, 700, 10.1161/01.HYP.0000035524.10948.93
Seshiah, 2002, Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators, Circ. Res., 91, 406, 10.1161/01.RES.0000033523.08033.16
Murasawa, 1998, Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor, Circ. Res., 82, 1338, 10.1161/01.RES.82.12.1338
Wang, 2000, Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca2+ levels, J. Biol. Chem., 275, 12223, 10.1074/jbc.275.16.12223
Ushio-Fukai, 2001, Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells, Arterioscler. Thromb. Vasc. Biol., 21, 489, 10.1161/01.ATV.21.4.489
Bokemeyer, 2000, Angiotensin II-induced growth of vascular smooth muscle cells requires an Src-dependent activation of the epidermal growth factor receptor, Kidney Int., 58, 549
Ushio-Fukai, 2005, cAbl tyrosine kinase mediates reactive oxygen species- and caveolin-dependent AT1 receptor signaling in vascular smooth muscle: role in vascular hypertrophy, Circ. Res., 97, 829, 10.1161/01.RES.0000185322.46009.F5
Eguchi, 2001, Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK, J. Biol. Chem., 276, 7957, 10.1074/jbc.M008570200
Uchiyama-Tanaka, 2001, Angiotensin II signaling and HB-EGF shedding via metalloproteinase in glomerular mesangial cells, Kidney Int., 60, 2153, 10.1046/j.1523-1755.2001.00067.x
Shah, 2004, Differential pathways of angiotensin II-induced extracellularly regulated kinase 1/2 phosphorylation in specific cell types: role of heparin-binding epidermal growth factor, Mol. Endocrinol., 18, 2035, 10.1210/me.2003-0476
Schafer, 2004, Distinct ADAM metalloproteinases regulate G protein- coupled receptor-induced cell proliferation and survival, J. Biol. Chem., 279, 47929, 10.1074/jbc.M400129200
Mifune, 2005, G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor, J. Biol. Chem., 280, 26592, 10.1074/jbc.M502906200
Ohtsu, 2006, ADAM17 mediates epidermal growth factor receptor transactivation and vascular smooth muscle cell hypertrophy induced by angiotensin II, Arterioscler. Thromb. Vasc. Biol., 26, e133, 10.1161/atvb.26.9.1976
Seta, 2003, Phosphorylation of tyrosine 319 of the angiotensin II type 1 receptor mediates angiotensin II-induced trans-activation of the epidermal growth factor receptor, J. Biol. Chem., 278, 9019, 10.1074/jbc.M208017200
Zhai, 2006, An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy, Circ. Res., 99, 528, 10.1161/01.RES.0000240147.49390.61
Feng, 2005, Unconventional homologous internalization of the angiotensin II type-1 receptor induced by G-protein-independent signals, Hypertension, 46, 419, 10.1161/01.HYP.0000172621.68061.22
Miura, 2004, Activation of extracellular signal-activated kinase by angiotensin II-induced Gq-independent epidermal growth factor receptor transactivation, Hypertens. Res., 27, 765, 10.1291/hypres.27.765
Seals, 2003, The ADAMs family of metalloproteases: multidomain proteins with multiple functions, Genes Dev., 17, 7, 10.1101/gad.1039703
Tanaka, 2004, ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands, J. Biol. Chem., 279, 41950, 10.1074/jbc.M400086200
Mori, 2003, PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor, J. Biol. Chem., 278, 46029, 10.1074/jbc.M306393200
Diaz-Rodriguez, 2002, Extracellular signal-regulated kinase phosphorylates tumor necrosis factor α-converting enzyme at threonine 735: a potential role in regulated shedding, Mol. Biol. Cell, 13, 2031, 10.1091/mbc.01-11-0561
Fischer, 2004, Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor, Mol. Cell. Biol., 24, 5172, 10.1128/MCB.24.12.5172-5183.2004
Zhang, 2006, Phosphorylation of TNF-α converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation, Proc. Natl. Acad. Sci. U.S.A., 103, 6901, 10.1073/pnas.0509719103
Saito, 2002, Metalloprotease inhibitor blocks angiotensin II-induced migration through inhibition of epidermal growth factor receptor transactivation, Biochem. Biophys. Res. Commun., 294, 1023, 10.1016/S0006-291X(02)00595-8
Lautrette, 2005, Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach, Nat. Med., 11, 867, 10.1038/nm1275
Heeneman, 2000, Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor β receptor. Key role for the p66 adaptor protein Shc, J. Biol. Chem., 275, 15926, 10.1074/jbc.M909616199
Suzuki, 2006, Growth factor receptor transactivation in mediating end organ damage by angiotensin II, Hypertension, 47, 339, 10.1161/01.HYP.0000202497.83294.50
Schellings, 2006, Imatinib attenuates end-organ damage in hypertensive homozygous TGR(mRen2)27 rats, Hypertension, 47, 467, 10.1161/01.HYP.0000202487.68969.f7
Mondorf, 2000, Involvement of the platelet-derived growth factor receptor in angiotensin II-induced activation of extracellular regulated kinases 1 and 2 in human mesangial cells, FEBS Lett., 472, 129, 10.1016/S0014-5793(00)01433-2
Kim, 2000, In vivo activation of rat aortic platelet-derived growth factor and epidermal growth factor receptors by angiotensin II and hypertension, Arterioscler. Thromb. Vasc. Biol., 20, 2539, 10.1161/01.ATV.20.12.2539
Kelly, 2004, Platelet-derived growth factor receptor transactivation mediates the trophic effects of angiotensin II in vivo, Hypertension, 44, 195, 10.1161/01.HYP.0000132883.20764.12
Saito, 2002, Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-δ and c-Src, J. Biol. Chem., 277, 44695, 10.1074/jbc.M208332200
Gao, 2006, Angiotensin II stimulates phosphorylation of an ectodomain-truncated platelet-derived growth factor receptor-β and its binding to class IA PI3K in vascular smooth muscle cells, Biochem. J., 397, 337, 10.1042/BJ20060095
Zahradka, 2004, Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase, Endocrinology, 145, 2978, 10.1210/en.2004-0029
Touyz, 2003, Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation, Can. J. Physiol. Pharmacol., 81, 159, 10.1139/y02-164
Noma, 2006, Physiological role of ROCKs in the cardiovascular system, Am. J. Physiol. Cell Physiol., 290, C661, 10.1152/ajpcell.00459.2005
Seko, 2003, Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle, Circ. Res., 92, 411, 10.1161/01.RES.0000059987.90200.44
Yamakawa, 2000, Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells, Hypertension, 35, 313, 10.1161/01.HYP.35.1.313
Ushio-Fukai, 1998, Temporal dispersion of activation of phospholipase C-β1 and -γ isoforms by angiotensin II in vascular smooth muscle cells. Role of αq/11, α12, and βγ G protein subunits, J. Biol. Chem., 273, 19772, 10.1074/jbc.273.31.19772
Gohla, 2000, Role for G12/G13 in agonist-induced vascular smooth muscle cell contraction, Circ. Res., 87, 221, 10.1161/01.RES.87.3.221
Nishida, 2005, Gα12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes, J. Biol. Chem., 280, 18434, 10.1074/jbc.M409710200
Fujii, 2005, Gα12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts, J. Biol. Chem., 280, 23041, 10.1074/jbc.M409397200
Wettschureck, 2002, Rho/Rho-kinase mediated signaling in physiology and pathophysiology, J. Mol. Med., 80, 629, 10.1007/s00109-002-0370-2
Lee, 2004, Hypertension and RhoA/Rho-kinase signaling in the vasculature: highlights from the recent literature, Hypertension, 44, 796, 10.1161/01.HYP.0000148303.98066.ab
Lutz, 2005, The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA, J. Biol. Chem., 280, 11134, 10.1074/jbc.M411322200
Wakino, 2004, Peroxisome proliferator-activated receptor γ ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2, Circ. Res., 95, e45, 10.1161/01.RES.0000142313.68389.92
Barnes, 2005, β-Arrestin 1 and Gαq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation, J. Biol. Chem., 280, 8041, 10.1074/jbc.M412924200
Ohtsu, 2005, Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II, Arterioscler. Thromb. Vasc. Biol., 25, 1831, 10.1161/01.ATV.0000175749.41799.9b
Kyaw, 2004, Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cells via extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation, Mol. Pharmacol., 65, 832, 10.1124/mol.65.4.832
Cui, 2006, RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor κB/RelA subunit exchange on the interleukin-6 promoter in VSMCs, Circ. Res., 99, 723, 10.1161/01.RES.0000244015.10655.3f
Takeda, 2001, Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression, Arterioscler. Thromb. Vasc. Biol., 21, 868, 10.1161/01.ATV.21.5.868
Funakoshi, 2001, Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells, Hypertension, 38, 100, 10.1161/01.HYP.38.1.100
Ryan, 2004, Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice, Hypertension, 43, 1074, 10.1161/01.HYP.0000123074.89717.3d
Jin, 2006, Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats, J. Pharmacol. Exp. Ther., 318, 288, 10.1124/jpet.105.100735
Higashi, 2003, Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system, Circ. Res., 93, 767, 10.1161/01.RES.0000096650.91688.28
Wang, 2005, Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis, Circulation, 111, 2219, 10.1161/01.CIR.0000163544.17221.BE
Rikitake, 2005, Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/− haploinsufficient mice, Circulation, 112, 2959, 10.1161/CIRCULATIONAHA.105.584623
Watanabe, 2005, Angiotensin II and the endothelium: diverse signals and effects, Hypertension, 45, 163, 10.1161/01.HYP.0000153321.13792.b9
Cai, 2000, Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress, Circ. Res., 87, 840, 10.1161/01.RES.87.10.840
Luscher, 2000, Endothelial dysfunction: the role and impact of the renin-angiotensin system, Heart, 84, i20, 10.1136/heart.84.suppl_1.i20
Mancini, 1996, Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study, Circulation, 94, 258, 10.1161/01.CIR.94.3.258
Prasad, 2000, Acute and chronic angiotensin-1 receptor antagonism reverses endothelial dysfunction in atherosclerosis, Circulation, 101, 2349, 10.1161/01.CIR.101.20.2349
Nickenig, 2002, The AT1-type angiotensin receptor in oxidative stress and atherogenesis: part I: oxidative stress and atherogenesis, Circulation, 105, 393, 10.1161/hc0302.102618
Patel, 2000, Cell signaling by reactive nitrogen and oxygen species in atherosclerosis, Free Radical Biol. Med., 28, 1780, 10.1016/S0891-5849(00)00235-5
Wattanapitayakul, 2000, Endothelial dysfunction and peroxynitrite formation are early events in angiotensin- induced cardiovascular disorders, FASEB J., 14, 271, 10.1096/fasebj.14.2.271
Yan, 2003, Functional interplay between angiotensin II and nitric oxide: cyclic GMP as a key mediator, Arterioscler. Thromb. Vasc. Biol., 23, 26, 10.1161/01.ATV.0000046231.17365.9D
Suzuki, 2006, Activation of endothelial nitric oxide synthase by the angiotensin II type-1 receptor, Endocrinology, 147, 5914, 10.1210/en.2006-0834
Imanishi, 2006, Effects of angiotensin II on NO bioavailability evaluated using a catheter-type NO sensor, Hypertension, 48, 1058, 10.1161/01.HYP.0000248920.16956.d8
Ramchandran, 2006, Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response, Proc. Natl. Acad. Sci. U.S.A., 103, 19087, 10.1073/pnas.0602715103
Cai, 2002, NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II, J. Biol. Chem., 277, 48311, 10.1074/jbc.M208884200
Mulders, 2006, Sphingosine kinase-dependent activation of endothelial nitric oxide synthase by angiotensin II, Arterioscler. Thromb. Vasc. Biol., 26, 2043, 10.1161/01.ATV.0000237569.95046.b9
Mollnau, 2002, Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling, Circ. Res., 90, E58, 10.1161/01.RES.0000012569.55432.02
Chalupsky, 2005, Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase, Proc. Natl. Acad. Sci. U.S.A., 102, 9056, 10.1073/pnas.0409594102
Szabo, 2004, Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation, Mol. Med., 10, 28, 10.2119/2004-00001.Szabo
Andreozzi, 2004, Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells, Circ. Res., 94, 1211, 10.1161/01.RES.0000126501.34994.96
Costanzo, 2003, Endothelial activation by angiotensin II through NFκB and p38 pathways: Involvement of NFκB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin, J. Cell. Physiol., 195, 402, 10.1002/jcp.10191
Thai, 2003, Angiotensin subtype 1 receptor (AT1) blockade improves vasorelaxation in heart failure by up-regulation of endothelial nitric-oxide synthase via activation of the AT2 receptor, J. Pharmacol. Exp. Ther., 307, 1171, 10.1124/jpet.103.054916
Yayama, 2006, Angiotensin II stimulates endothelial NO synthase phosphorylation in thoracic aorta of mice with abdominal aortic banding via type 2 receptor, Hypertension, 48, 958, 10.1161/01.HYP.0000244108.30909.27
Marinissen, 2001, G-protein-coupled receptors and signaling networks: emerging paradigms, Trends. Pharmacol. Sci., 22, 368, 10.1016/S0165-6147(00)01678-3
Reiter, 2006, GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling, Trends. Endocrinol. Metab., 17, 159, 10.1016/j.tem.2006.03.008
Guo, 2001, The angiotensin II type 1 receptor and receptor-associated proteins, Cell Res., 11, 165, 10.1038/sj.cr.7290083
Ali, 1997, Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor, J. Biol. Chem., 272, 23382, 10.1074/jbc.272.37.23382
Venema, 1998, Angiotensin II-induced association of phospholipase Cgamma1 with the G-protein-coupled AT1 receptor, J. Biol. Chem., 273, 7703, 10.1074/jbc.273.13.7703
AbdAlla, 2000, AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration, Nature, 407, 94, 10.1038/35024095
AbdAlla, 2004, Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosis, Cell, 119, 343, 10.1016/j.cell.2004.10.006
Daviet, 1999, Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor, J. Biol. Chem., 274, 17058, 10.1074/jbc.274.24.17058
Lopez-Ilasaca, 2003, The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling, Mol. Biol. Cell, 14, 5038, 10.1091/mbc.e03-06-0383
Tsurumi, 2006, Interacting molecule of AT1 receptor, ATRAP, is colocalized with AT1 receptor in the mouse renal tubules, Kidney Int., 69, 488, 10.1038/sj.ki.5000130
Cui, 2000, ATRAP, novel AT1 receptor associated protein, enhances internalization of AT1 receptor and inhibits vascular smooth muscle cell growth, Biochem. Biophys. Res. Commun., 279, 938, 10.1006/bbrc.2000.4055
Tanaka, 2005, The novel angiotensin II type 1 receptor (AT1R)-associated protein ATRAP downregulates AT1R and ameliorates cardiomyocyte hypertrophy, FEBS Lett., 579, 1579, 10.1016/j.febslet.2005.01.068
Oshita, 2006, Attenuation of inflammatory vascular remodeling by angiotensin II type 1 receptor-associated protein, Hypertension, 48, 671, 10.1161/01.HYP.0000238141.99816.47
Guo, 2003, Type 1 angiotensin II receptor-associated protein ARAP1 binds and recycles the receptor to the plasma membrane, Biochem. Biophys. Res. Commun., 310, 1254, 10.1016/j.bbrc.2003.09.154
Guo, 2004, A novel angiotensin II type 1 receptor-associated protein induces cellular hypertrophy in rat vascular smooth muscle and renal proximal tubular cells, J. Biol. Chem., 279, 21109, 10.1074/jbc.M401544200
Guo, 2006, Development of hypertension and kidney hypertrophy in transgenic mice overexpressing ARAP1 gene in the kidney, Hypertension, 48, 453, 10.1161/01.HYP.0000230664.32874.52