Analysis of the structural and mechanical effects of procoagulant agents on neonatal fibrin networks following cardiopulmonary bypass

Journal of Thrombosis and Haemostasis - Tập 16 - Trang 2159-2167 - 2018
K. Nellenbach1,2, N.A. Guzzetta3, A.C. Brown1,2
1Joint Department of Biomedical Engineering, North Carolina State University and The University of North Carolina at Chapel Hill, Raleigh, NC, USA
2Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA
3Department of Anesthesiology, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA

Tài liệu tham khảo

Ignjatovic, 2011, Age‐related differences in plasma proteins: how plasma proteins change from neonates to adults, PLoS ONE, 6, e17213, 10.1371/journal.pone.0017213 Ignjatovic, 2011, The coagulation system in children: developmental and pathophysiological considerations, Semin Thromb Hemost, 37, 723, 10.1055/s-0031-1297162 Revel‐Vilk, 2012, The conundrum of neonatal coagulopathy, Hematology Am Soc Hematol Educ Program, 2012, 450, 10.1182/asheducation.V2012.1.450.3798660 Brown, 2016, Fibrin network changes in neonates after cardiopulmonary bypass, Anesthesiology, 124, 1021, 10.1097/ALN.0000000000001058 Guzzetta, 2015, Excessive postoperative bleeding and outcomes in neonates undergoing cardiopulmonary bypass, Anesth Analg, 120, 405, 10.1213/ANE.0000000000000531 Wolf, 2014, Early postoperative bleeding is independently associated with increased surgical mortality in infants after cardiopulmonary bypass, J Thorac Cardiovasc Surg, 148, 631, 10.1016/j.jtcvs.2013.10.050 Manlhiot, 2011, Risk, clinical features, and outcomes of thrombosis associated with pediatric cardiac surgery, Circulation, 124, 1511, 10.1161/CIRCULATIONAHA.110.006304 Undas, 2014, Fibrin clot properties and their modulation in thrombotic disorders, Thromb Haemost, 112, 32, 10.1160/TH14-01-0032 Undas, 2011, Fibrin clot structure and function: a role in the pathophysiology of arterial and venous thromboembolic diseases, Arterioscler Thromb Vasc Biol, 31, e88, 10.1161/ATVBAHA.111.230631 Awad, 2013, Activated prothrombin complex concentrates for the reversal of anticoagulant‐associated coagulopathy, Pharm Ther, 38, 696 Jeremy H. PCC Dosing Information. [online] University of Missouri‐Kansas City School Of Medicine. Available at: http://med.umkc.edu/docs/em/PCC_dosing_information.pdf. Kcentra.com. Dosage Calculator Kcentra® (Prothrombin complex concentrate [human]). 2018 [online] Available at: https://www.kcentra.com/dosagecalculator?gclid=Cj0KCQjwz93cBRCrARIsAEFbWsiW19KTEnHjyfluPCaSpgIj57y-ExLgQTxmNnk2zxRucDkK07q0FFsaAlNQEALw_wcB. Prescriber's Digital Referennce Coagulation factor VIIa recombinant‐ Drug Summary. 2018 [online] Available at: http://www.pdr.net/drug-summary/NovoSeven-RT-coagulation-factor-VIIa--recombinant--458 Sproul E, Nandi S, Brown AC. Methods in Molecular Biology‐Biomaterials. New York, NY: Springer, in press. Brown, 2015, Molecular interference of fibrin's divalent polymerization mechanism enables modulation of multiscale material properties, Biomaterials, 49, 27, 10.1016/j.biomaterials.2015.01.010 Timmins, 2010, Structural inhomogeneity and fiber orientation in the inner arterial media, Am J Physiol Heart Circ Physiol, 298, H1537, 10.1152/ajpheart.00891.2009 Franklin, 2016, Optimizing thrombin generation with 4‐factor prothrombin complex concentrates in neonatal plasma after cardiopulmonary bypass, Anesth Analg, 122, 935, 10.1213/ANE.0000000000001098 Allen, 2004, Impact of procoagulant concentration on rate, peak and total thrombin generation in a model system, J Thromb Haemost, 2, 402, 10.1111/j.1538-7933.2003.00617.x Zeng, 2017, Effectiveness of prothrombin complex concentrate (PCC) in neonates and infants with bleeding or risk of bleeding: a systematic review and meta‐analysis, Eur J Pediatr, 176, 581, 10.1007/s00431-017-2877-0 Mitsiakos, 2007, Is the use of rFVIIa safe and effective in bleeding neonates? A retrospective series of 8 cases, J Pediatr Hematol Oncol, 29, 145, 10.1097/MPH.0b013e3180335bcb Tran, 2013, Biomechanics of haemostasis and thrombosis in health and disease: from the macro‐ to molecular scale, J Cell Mol Med, 17, 579, 10.1111/jcmm.12041 Weisel, 2010, Biomechanics in hemostasis and thrombosis, J Thromb Haemost, 8, 1027, 10.1111/j.1538-7836.2010.03808.x Weisel, 2008, The biochemical and physical process of fibrinolysis and effects of clot structure and stability on the lysis rate, Cardiovasc Hematol Agents Med Chem, 6, 161, 10.2174/187152508784871963 Longstaff, 2011, The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies, Blood, 117, 661, 10.1182/blood-2010-06-290338 Undas, 2017, Prothrombotic fibrin clot phenotype in patients with deep vein thrombosis and pulmonary embolism: a new risk factor for recurrence, Biomed Res Int, 2017, 8196256, 10.1155/2017/8196256 Collet, 1996, Fibrinogen Dusart: electron microscopy of molecules, fibers and clots, and viscoelastic properties of clots, Biophys J, 70, 500, 10.1016/S0006-3495(96)79596-6 Faraoni, 2017, Relationship between transfusion of blood products and the incidence of thrombotic complications in neonates and infants undergoing cardiac surgery, J Cardiothorac Vasc Anesth, 6, 1943, 10.1053/j.jvca.2017.04.039