An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid

Brain Research - Tập 247 Số 1 - Trang 184-187 - 1982
M.N. Perkins1, Trevor W. Stone1
1Department of Physiology, St. George's Hospital Medical School, Cranmer Terrace, Tooting, London SW17 ORE U.K.

Tóm tắt

Từ khóa


Tài liệu tham khảo

Lapin, 1978, Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice, J. Neurol. Transm., 42, 37, 10.1007/BF01262727

Lapin, 1978, Convulsions and tremor in immature rats after intraperitoneal injection of kynurenine and its metabolites, Pharmacol. Res. Commun., 10, 81, 10.1016/S0031-6989(78)80065-4

Lapin, 1979, Effect of kynurenine and quinolinic acid on the action of convulsants in mice, Pharmacol. Biochem. Behav., 13, 17

Lapin, 1981, Kynurenine and seizures, Epilepsia, 22, 257, 10.1111/j.1528-1157.1981.tb04108.x

Lapin, 1981, Nicotanamide, inosine and hypoxanthine, putative endogenous ligands of the benzodiazepine receptor, opposite to diazepam are much more effective against kynurenine-induced seizures than against pentylenetetrazol-induced seizures, Pharmacol. Biochem. Behav., 14, 589, 10.1016/0091-3057(81)90117-9

Mahler, 1971

Stone, 1973, Cortical pyramidal tract interneurones and their sensitivity to L-glutamic acid, J. Physiol. (Lond.), 233, 211, 10.1113/jphysiol.1973.sp010306

Stone, 1981, Quinolinic acid. A potent endogenous excitant at amino acid receptors in CNS, Europ. J. Pharmacol., 72, 411, 10.1016/0014-2999(81)90587-2

Watkins, 1981, Pharmacology of receptors for excitatory amino acids, 263