An immunological biomarker to predict MTX response in early RA
Tóm tắt
Từ khóa
Tài liệu tham khảo
Harris, 1990, Rheumatoid arthritis. Pathophysiology and implications for therapy, N Engl J Med, 322, 1277, 10.1056/NEJM199005033221805
Nell, 2004, Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis, Rheumatology, 43, 906, 10.1093/rheumatology/keh199
Quinn, 2003, Window of opportunity in early rheumatoid arthritis: possibility of altering the disease process with early intervention, Clin Exp Rheumatol, 21, 154
Quinn, 2005, Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal—Results from a twelve-month randomized, double-blind, placebo-controlled trial, Arthritis Rheum, 52, 27, 10.1002/art.20712
Emery, 2012, Combination etanercept and methotrexate provides better disease control in very early (≤4 months) versus early rheumatoid arthritis (>4 months and <2 years): post hoc analyses from the COMET study, Ann Rheum Dis, 71, 989, 10.1136/annrheumdis-2011-201066
Smolen, 2010, Treating rheumatoid arthritis to target: recommendations of an international task force, Ann Rheum Dis, 69, 631, 10.1136/ard.2009.123919
Smolen, 2010, EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs, Ann Rheum Dis, 69, 964, 10.1136/ard.2009.126532
Katchamart, 2010, Predictors for remission in Rheumatoid Arthritis patients: a systematic review, Arthritis Care Res, 62, 1128, 10.1002/acr.20188
Ponchel, 2012, CD4+ T-cell subsets in rheumatoid arthritis, Int J Clin Rheumtol, 7, 37, 10.2217/ijr.11.69
Ponchel, 2002, Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis, Blood, 100, 4550, 10.1182/blood-2002-03-0671
Ponchel, 2005, IL-7 deficiency and therapy-induced lymphopenia in Rheumatoid Arthritis, Arthritis Res Ther, 7, 80, 10.1186/ar1452
Saleem, 2010, Patients with RA in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped?, Ann Rheum Dis, 69, 1636, 10.1136/ard.2009.117341
Lawson, 2006, Rheumatoid Arthritis is associated with a deficit in CD4+CD25high regulatory T-cell in the peripheral blood, Rheumatology, 45, 1210, 10.1093/rheumatology/kel089
Conaghan, 2003, Elucidation of the relationship between synovitis and bone damage: a randomized magnetic resonance imaging study of individual joints in patients with early rheumatoid arthritis, Arthritis Rheum, 48, 64, 10.1002/art.10747
Burgoyne, 2008, Abnormal T-cell differentiation persists in rheumatoid arthritis patients in clinical remission and predicts relapse, Ann Rheum Diseases, 67, 750, 10.1136/ard.2007.073833
Baecher-Allan, 2002, Inhibition of Human CD4+CD25+high Regulatory T Cell Function, J Immunol, 169, 6210, 10.4049/jimmunol.169.11.6210
Hori, 2003, Control of regulatory T cell development by the transcription factor Foxp3, Science, 299, 1057, 10.1126/science.1079490
Liu, 2006, CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells, J Exp Med, 203, 1701, 10.1084/jem.20060772
Hyrich, 2006, British Soc Rheumatology. Comparison of the response to infliximab or etanercept monotherapy with the response to cotherapy with methotrexate or another disease-modifying antirheumatic drug in patients with rheumatoid arthritis—Results from the British Society for Rheumatology Biologics Register, Arthritis Rheum, 54, 1786, 10.1002/art.21830
Hyrich, 2006, Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register, Rheumatology, 45, 1558, 10.1093/rheumatology/kel149
Burmester, 2008, Clinical remission and/or minimal disease activity in patients receiving adalimumab treatment in a multinational, open-label, twelve-week study, Arthritis Rheum, 59, 32, 10.1002/art.23247
Emery, 2008, Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial, Lancet, 372, 375, 10.1016/S0140-6736(08)61000-4
Emery, 2010, Very early (<4 months) treatment with combination etanercept and methotrexate produces significantly better remission rates: results from the COMET study [abstract], Ann Rheum Dis, 69, S57
Pease, 1999, Does the age of onset of rheumatoid arthritis influence phenotype? a prospective study of outcome and prognostic factors, Rheumatology, 38, 228, 10.1093/rheumatology/38.3.228
Verstappen, 2005, A good response to early DMARD treatment of patients with rheumatoid arthritis in the first year predicts remission during follow up, Ann Rheum Dis, 64, 38, 10.1136/ard.2003.014928
Forslind, 2007, Sex: a major predictor of remission in early rheumatoid arthritis?, Ann Rheum Dis, 66, 46, 10.1136/ard.2006.056937
Anderson, 2000, Factors predicting response to treatment in rheumatoid arthritis—The importance of disease duration, Arthritis Rheum, 43, 22, 10.1002/1529-0131(200001)43:1<22::AID-ANR4>3.0.CO;2-9
Bukhari, 2003, Influence of disease-modifying therapy on radiographic outcome in inflammatory polyarthritis at five years—Results from a large observational inception study, Arthritis Rheum, 48, 46, 10.1002/art.10727
Gregersen, 1987, The shared epitope hypothesis—an approach to understanding the molecular-genetics of susceptibility to rheumatoid- arthritis, Arthritis Rheum, 30, 1205, 10.1002/art.1780301102
Panayi, 1992, The importance of the T-Cell in initiating and maintaining the chronic synovitis of rheumatoid-arthritis, Arthritis Rheum, 35, 729, 10.1002/art.1780350702
Matthews, 1992, Rheumatoid synovial T-Cell dysfunction can be explained by low Cd45rb expression, Arthritis Rheum, 35, S224
Matthews, 1993, Subpopulations of Primed-T Helper-Cells in Rheumatoid-Arthritis, Arthritis Rheum, 36, 603, 10.1002/art.1780360505
Winchester, 1994, The molecular-basis of susceptibility to rheumatoid-arthritis, Adv Immunol, 389, 10.1016/S0065-2776(08)60456-3
Salmon, 1995, The role of lymphocytes in rheumatoid arthritis, Br Med Bull, 51, 332, 10.1093/oxfordjournals.bmb.a072964
Panayi, 1996, T cell hypothesis in rheumatoid arthritis (RA) tested by humanised non-depleting anti-CD4 monoclonal antibody (mAb) treatment. 1. Suppression of disease activity and acute phase response, Immunology, 89, 379