Alzheimer’s disease

Adolfson, R., Gottfries C. G., Roos B. E., and Winblad B. (1979) Changes in brain catecholamines in patients with dementia of the Alzheimer type.Brit. J. Psychiatry 135, 216–223.

Andria-Waltenbaugh A. M. and Puck T. T. (1977) Alzheimer’s disease: further evidence of a microtubular defect.J. Cell. Biol. 75, 279a.

Averback P. (1983) Two new lesions in Alzheimer disease.Lancet 2, 1203.

Bertagnolio B., Uziel G., Bottacchi E., Crenna G., D’Angelo A., and DiDonato S. (1980) Friedreich’s ataxia. II. Biochemical studies in cultured cells.Ital. J. Neurol. Sci. 1, 239–243.

Bird E. D., Gale G. S., and Spokes E. G. (1977) Huntington’s chorea: Postmortem activity of enzymes involved in cerebral glucose metabolism.J. Neurochem. 29, 539–546.

Blass J. P., Gibson G. E., Duffy T. E., and Plum F. (1981) Cholinergic dysfunction: a common denominator in metabolic encephalopathies, inCholinergic Mechanisms: Phylogenetic Aspects, Central and Peripheral Synapses, and Clinical Significance (Pepeu G. and Ladinsky H., eds.), pp. 921–928. Plenum Press, New York.

Blass J. P., Hanin I., Barclay L., Kopp U., and Reding M. (1984) Elevated red cell to plasma choline ratios in Alzheimer’s disease, inDynamics of Cholinergic Function (Hanin I., ed.), Plenum Press, New York.

Blass J. P., Kark R. A. P., Menon N., and Harris S. H. (1976) Decreased activities of the pyruvate and ketoglutarate dehydrogenase complexes in fibroblasts from five patients with Friedreich’s ataxia.N. Engl. J. Med. 295, 62–66.

Blass J. P. and Weksler M. C. (1983) Toward an effective treatment of Alzheimer’s disease.Ann. Intern. Med. 98, 251–253.

Bondareff W., Mountjoy C. Q., and Roth M. (1981) Selective loss of neurones of origin of adrenergic projections to cerebral cortex (nucleus locus coeruleus) in senile dementia.Lancet 1, 783–784.

Bowen D. M., Allen S. J., Benton J. S., Goodhart M. J., Haan E. A., Palmer A. M., Sims N. R., Smith C. C. T., Spillane J. A., Esir M. M., Neary D., Snowdon J. S., Wilcock G. K., and Davison A. N. (1983) Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer’s disease.J. Neurochem. 41, 266–272.

Bowen D. M., Smith C. B., White P., and Davison A. N. (1976) Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies.Brain 99, 459–496.

Bowen D. M., White P., Spillane J. A., Goodhart M. J., Curzon G., Iwangoff P., Meier-Ruge W., and Davidson A. N. (1979). Accelerated aging or selective neuronal loss as an important cause of dementia.Lancet 1, 11–13.

Browning M., Baudry M., and Lynch G. (1982) Evidence that high-frequency stimulation influences the phosphorylation of pyruvate dehydrogenase, and that the activity of this enzyme is linked to mitochondrial calcium sequestration.Prog. Brain Res. 56, 317–337.

Coyle J. T., Price D. L., and DeLong M. R. (1983) Alzheimer’s disease: A disorder of cortical cholinergic innervation.Science 219, 1184–1190.

Crystal H. A. and Davies P. (1982) Cortical substance-P-like immunoreactivity in cases of Alzheimer’s disease and senile dementia of the Alzheimer type.J. Neurochem. 38, 1781–1784.

Davies P. and Maloney A. J. F. (1976) Selective loss of central cholinergic neurones in Alzheimer’s disease.Lancet 2, 1403.

Diamond J. M., Matsuyama S. S., Meier K., and Jarvik L. F. (1983) Elevation of erythrocyte countertransport in Alzheimer’s dementia.N. Engl. J. Med. 309, 1061–1062.

Dijkstra U. J., Willems J. L., Joosten E. M. G., and Gabreels F. J. M. (1983) Friedreich ataxia and low pyruvate carboxylase activity in liver and fibroblasts.Ann. Neurol. 13, 325–327.

Drachman D. A. and Leavitt J. (1974) Human memory and the cholinergic system. Relation to aging.Arch. Neurol. 30, 113–121.

Folstein M. F. and Breitner J. C. S. (1981) Language disorder predicts familial Alzheimer disease.Johns Hopkins Med. J. 149, 145–147.

Foster N. L., Chase T. N., Redio P., Patronas N. J., Brooks R. A., and DiChuro G. (1983) Alzheimer’s disease: Focal cortical changes shown by positron emission tomography.Neurology 33, 961–965.

Garcia C. A., Reding M. J., and Blass J. P. (1981) Overdiagnosis of dementia.J. Am. Geriatr. Soc. 29, 407–410.

Gibson G. E. and Peterson C. (1981) Aging decreases oxidative metabolism and the release and synthesis of acetylcholine.J. Neurochem. 37, 978–984.

Gibson G. E. and Peterson C. (1983) Acetylcholine and oxidative metabolism in septum and hippocampus in vitro.J. Biol. Chem. 258, 1142–1145.

Gibson G. E., Pulsinelli W. A., Blass J. P., and Duffy T. E. (1981) Brain dysfunction in mild to moderate hypoxia.Am. J. Med. 70, 1247–1254.

Gottfries C. G., Gottfries I., and Ross B. E. (1969) The investigation of homovanillic acid in the human brain and its correlation to senile dementia.Br. J. Psychiatry 115, 563–574.

Hirsch J. A. and Gibson G. E. (1982) Anoxia inhibits release of acetylcholine but not of norepinephrine from rat brain slices.Fed. Proc. 41, 8738.

Ingvar D. H. and Lassen N. A., eds. (1975) The coupling of function, metabolism and blood flow in the brain, pp. 1–523. Munksgaard, Copenhagen.

Jarvik L. F., Matsuyama S.S., Kessler J. O., Fu T. K., Tsai S. Y., and Clark E. O. (1982) Philothermal response of polymorphonuclear leukocytes in dementia of the Alzheimer type.Neurobiol. Aging 3, 93–99.

Krause L. J. (1983) Decreased natural killer cell activity in Alzheimer’s disease.Neurosci. Abstr. 9, 115.

Ksiezak-Reding H., Murphy C., and Blass J. P. (1983) Enzyme activities in platelets from patients with Alzheimer disease.Age 6, 11.

Larsson T., Sjogren T., and Jacobson G. (1983) Senile dementia—A clinical, sociomedical and genetic study.Acta Psychiatr. Scand., Suppl. 167, 39–150.

Lowry O. H. and Passonneau J. V. (1964) The relationships between substrates and enzymes of glycolysis in brain.J. Biol. Chem. 239, 31–42.

Markesberry W. R., Leung P. K., and Butterfield D. A. (1980) Spin label and biochemical studies of erythrocyte membranes in Alzheimer’s disease.J. Neurol. Sci. 45, 232–330.

Miller A. E., Neighbour P. A., Katzman R., Aronson M., and Lipkowitz R. (1981) Immunologic studies in senile dementia of the Alzheimer type: Evidence of enhanced suppressor cell activity.Ann. Neurol. 10, 506–510.

Nordenson I., Adolfson R., Beckman G., Bucht G., and Winblad G. (1980) Chromosomal abnormality in dementia of Alzheimer type.Lancet 1, 481–482.

Perry E. K., Perry R. H., Blessed G., and Tomlinson B. E. (1977) Necropsy evidence of central cholinergic deficits in senile dementia.Lancet 2, 189.

Perry E. K., Perry R. H., Tomlinson B. E., Blessed G., and Gibson P. H. (1980) Coenzyme-A-acetylating enzymes in Alzheimer’s disease: possible cholinergic “compartment” of pyruvate dehydrogenase.Neurosci. Lett. 18, 105–110.

Perry E. K., Tomlinson B. E., Blessed G., Perry R. H., Cross A. J., and Crow T. (1981) Noradrenergic and cholinergic systems in senile dementia of Alzheimer type.Lancet 2, 149.

Perry R. H., Wilson I. E., Bober M. J., Atack J., Blessed G., Tomlinson B. E., and Perry E. K. (1982) Plasma and erythrocyte acetylcholinesterase in senile dementia of Alzheimer type.Lancet 1, 174–175.

Plaitakis A., Berl S., and Yahr M. O. (1984) Neurological disorders associated with deficiency of glutamate dehydrogenase.Ann. Neurol. 15, 144–153.

Prusiner S. B., McKinley M. P., Bowman K. A., Bolton D. C., Bendheim P. E., Groth D. F., and Glenner G. S. (1983) Scrapie prions aggregate to form amyloid-like birefringent rods.Cell 35, 349–358.

Reding M. J., Haycox J., Wigforss K., Brush D., and Blass J. P. (1984) Outcome of patients referred to a dementia service.J. Am. Geriatr. Soc. (in press).

Risberg J. (1980) Regional cerebral blood flow measurements by133Xe-inhalation: methodology and applications in neuropsychology and psychiatry.Brain Lang. 9, 9–34.

Robbins J. H., Otsuka F., Tarone R. E., Polinsky R. J., Brunback R. A., Moshell A. N., Nee L. E., Ganges M. B., and Cayeux S. T. (1983) Radiosensitivity in Alzheimer disease and Parkinson disease.Lancet 1, 468–469.

Ropper A. H. and Williams R. S. (1980) Relationship between plaques, tangles and dementia in Down syndrome.Neurology 30, 639–644.

Rosser M. N. (1981) Parkinson’s disease and Alzheimer’s disease: disorders of the isodendritic core.Br. Med. J. 283, 1588–1590.

Routtenberg A. (1982) Identification and back titration of brain pyruvate dehydrogenase: functional significance for behavior.Prog. Brain Res. 56, 349–374.

Siesjo B. K. (1978)Brain Energy Metabolism, Wiley, New York.

Sims N. R., Bowen D. M., Allen S. J., Smith C. T. T., Neary D., Thomas D. J., and Davison A. N. (1983a) Presynaptic cholinergic dysfunction in patients with dementia.J. Neurochem. 40, 503–509.

Sims N. R., Bowen D. M., Neary D., and Davison A. N. (1983b) Metabolic processes in Alzheimer’s disease: Adenine nucleotide content and production of14CO2 from [U-14C]glucose in vitro in human neocortex.J. Neurochem. 41, 1329–1334.

Sokoloff L. (1966) Cerebral circulatory and metabolic changes associated with aging.Res. Publ. Assoc. Res. Nerv. Ment. Dis. 41, 237–265.

Sorbi S., Bird E. D., and Blass J. P. (1983) Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain.Ann. Neurol. 13, 72–78.

Stumpf D. A., Parks J. K., Eguren L. A., and Haas R. (1982) Friedreich ataxia. III. Mitochondrial malic enzyme deficiency.Neurology 32, 221–228.

Terry R. D. (1978) Senile dementia.Fed. Proc. 37, 2837–2840.

Terry R. D., Peck A., DeTeresa R., Schechter R., and Horoupian D. S. (1981) Some morphometric aspects of the brain in senile dementia of the Alzheimer type.Ann. Neurol. 10, 184–192.

Thomas L. (1981) On the problem of dementia.Discover (Aug.) 34–36.

Zemcov A., Risberg J., Barclay L., and Blass, J. P. (1983) A double-blind study of rCBF in the differential diagnosis of dementias.Eur. Neurol. 22, 20.